CAS No. 6284-40-8
Batch:
Purity:100
Chemical Structure
Check the
Meglumine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 6284-40-8 | |
|---|---|---|
| Molecular Formula |
C7H17NO5 |
|
| Molecular Weight (MW) | 195.21 | |
| SMILES | CNCC(C(C(C(CO)O)O)O)O |
Biological Activity
Meglumine is an amino sugar derived from sorbitol that exhibits antiproliferative activity against THP-1 human acute monocytic leukemia cells. As an organic base and sugar alcohol derivative, it modulates cellular viability and osmotic balance in monocytic cell lines. Treatment with meglumine impairs leukemic cell growth and reduces THP-1 monocytic cell survival, serving as a functional small molecule for studying cellular responses and metabolic processing in monocytic leukemia models. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
39 mg/mL
(199.78 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 39 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Reference
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Note: Technical data last updated: Sep 1, 2026.