MCC950 Sodium: Selectivity & Specificity
MCC950 Sodium is a potent inhibitor of NLRP3 inflammasome (< 10 nM), NEK7, Aβ1–42, tau protein, MHC-I, pyroptosis, IL-1β, ASC, carbonic anhydrase, Aβ, IL-18. MCC950 Sodium exhibits the greatest inhibitory potency toward NLRP3 inflammasome (IC50 = < 10 nM).