MCC950 Sodium is a potent, highly selective NLRP3 inflammasome inhibitor. It affects NLRP3 signaling by binding to the NACHT domain to block oligomerization, effectively inhibiting inflammasome activation and the subsequent release of pro-inflammatory cytokines IL-1β and IL-18.
MCC950 Sodium IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for MCC950 Sodium Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.