CAS No. 2097938-73-1
Batch:
Purity:99.84
Chemical Structure
Check the
MBQ-167
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 9-ethyl-3-(5-phenyltriazol-1-yl)carbazole | |
|---|---|---|
| CAS Number | 2097938-73-1 | |
| Molecular Formula |
C22H18N4 |
|
| Molecular Weight (MW) | 338.41 | |
| SMILES | CCN1C2=C(C=C(C=C2)N3C(=CN=N3)C4=CC=CC=C4)C5=CC=CC=C51 | |
| InChIKey | LJCANTASZGYJLG-UHFFFAOYSA-N |
MBQ-167 is a potent dual inhibitor of Rac and Cdc42. By suppressing the activation of Rac and Cdc42 GTPases, MBQ-167 inhibits downstream PAK effector signaling and disrupts actin cytoskeleton reorganization. Consequently, this small-molecule inhibitor reduces metastatic breast cancer cell migration, invasion, and viability, ultimately impairing primary tumor growth and metastatic progression in preclinical cancer models.
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
68 mg/mL
(200.93 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 14 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.