CAS No. 2188-68-3

Batch: Purity:99.81
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Lycorine hydrochloride Chemical Structure
Chemical Structure
Check the Lycorine hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (1S,17S,18S,19S)-5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,15-tetraene-17,18-diol;hydrochloride
CAS Number 2188-68-3
Molecular Formula

C16H17NO4.HCl
Molecular Weight (MW) 323.77
SMILES C1CN2CC3=CC4=C(C=C3C5C2C1=CC(C5O)O)OCO4.Cl
InChIKey VUVNTYCHKZBOMV-NVJKKXITSA-N

Ordering Information

Biological Activity

Lycorine hydrochloride is a natural Amaryllidaceae alkaloid exhibiting potent anticancer and antiviral activities, including inhibition of hepatitis C virus (HCV). It inhibits cancer cell proliferation and survival across multiple tumor models by inducing cell cycle arrest and apoptosis. Furthermore, lycorine suppresses key cell survival and signaling cascades, leading to attenuated tumor growth, migration, and metastatic potential. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 65 mg/mL (200.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.