Molecular Weight: 509.54 g/mol
Chemical Structure
Check the
Lirafugratinib (RLY-4008)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
20 mg/mL
(39.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 2 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Chemical Information
| IUPAC Name | N-[4-[4-amino-5-[3-fluoro-4-(4-methylpyrimidin-2-yl)oxyphenyl]-7-methylpyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-2-methylprop-2-enamide | |
|---|---|---|
| CAS Number | 2549174-42-5 | |
| Molecular Formula |
C28H24FN7O2 |
|
| Molecular Weight (MW) | 509.54 | |
| InChIKey | XOQVZSSDIQQUGO-UHFFFAOYSA-N |
Jump to
- Lirafugratinib (RLY-4008) Clinical Trials
- Lirafugratinib (RLY-4008) Solubility in DMSO
- Lirafugratinib (RLY-4008) Stock Solution
- Lirafugratinib (RLY-4008) Storage
- Lirafugratinib (RLY-4008) Stability
- Lirafugratinib (RLY-4008) CAS Number
- Lirafugratinib (RLY-4008) Chemical Structure (2D and 3D)
- Lirafugratinib (RLY-4008) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.