CAS No. 950455-15-9
Batch:
Purity:99.88
Chemical Structure
Check the
Liproxstatin-1
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-[(3-chlorophenyl)methyl]spiro[1,4-dihydroquinoxaline-3,4'-piperidine]-2-imine | |
|---|---|---|
| CAS Number | 950455-15-9 | |
| Molecular Formula |
C19H21ClN4 |
|
| Molecular Weight (MW) | 340.85 | |
| SMILES | C1CNCCC12C(=NCC3=CC(=CC=C3)Cl)NC4=CC=CC=C4N2 | |
| InChIKey | YAFQFNOUYXZVPZ-UHFFFAOYSA-N |
Liproxstatin-1 is a potent ferroptosis inhibitor with an IC50 of 22 nM. By suppressing lipid peroxidation and reactive oxygen species accumulation, Liproxstatin-1 blocks ferroptotic cell death without altering apoptotic or necroptotic signaling pathways. Consequently, it maintains mitochondrial integrity and protects cells against glutathione depletion and oxidative damage, preserving cellular viability across diverse experimental disease models.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
68 mg/mL
(199.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 18 mg/mL |
| Water | Insoluble |
| DMSO |
625 mg/mL
(1833.65 mM)
; Warmed with 60°C water bath
; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 34 mg/mL |
| Water | Insoluble |
| DMSO |
68 mg/mL
(199.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
68 mg/mL
(199.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Liproxstatin-1 Mechanism of Action: Lipid Peroxidation Inhibition in Cardiomyocytes Research
- Liproxstatin-1 Working Concentration | Cell Culture | Treatment
- Liproxstatin-1 Solubility in DMSO
- Liproxstatin-1 Stock Solution
- Liproxstatin-1 Storage
- Liproxstatin-1 Stability
- Liproxstatin-1 Combination Database
- Liproxstatin-1 Molecular Weight
- Liproxstatin-1 SMILES
- Liproxstatin-1 Chemical Structure (2D and 3D)
- Liproxstatin-1 Sigma (SML1414)? Try a better option.
- Liproxstatin-1 MedChemExpress (HY-12726)? Try a better option.
- Liproxstatin-1 Cayman (17730)? Try a better option.
- Liproxstatin-1 Tocris (6113)? Try a better option.
- Liproxstatin-1 Abcam (ab287002)? Try a better option.
- Liproxstatin-1 SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.