CAS No. 93572-42-0

Batch: Purity:98
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Lipopolysaccharides (LPS) Chemical Structure
Chemical Structure
Check the Lipopolysaccharides (LPS) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 93572-42-0
Molecular Formula

Biological Activity

Lipopolysaccharide (LPS) is a bacterial endotoxin and pathogen-associated molecular pattern that functions as an agonist of Toll-like receptor 4 (TLR4). Binding to TLR4 activates downstream signaling networks, including the NF-kB and MAPK pathways. This signaling triggers the release of pro-inflammatory cytokines, promotes innate immune responses, and stimulates the secretion of cell migrasomes in immune cells. [1][2]

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Water 50 mg/mL (超声加热五分钟)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Chow JC, et al. J Biol Chem. 1999;274(16):10689-92.

[2] Ma L, et al. Cell Res. 2015;25(1):24-38.

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Note: Technical data last updated: Sep 1, 2026.