CAS No. 55-06-1

Batch: Purity:98.58
Check CoA
Liothyronine Sodium Chemical Structure
Chemical Structure
Check the Liothyronine Sodium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 55-06-1
Molecular Formula

C15H12I3NO4.Na
Molecular Weight (MW) 672.96
SMILES C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)[O-])N)I)I)O.[Na+]

Ordering Information

Biological Activity

Liothyronine Sodium is a synthetic form of the thyroid hormone triiodothyronine (T3) that acts as a potent thyroid hormone receptor agonist. Upon binding to nuclear thyroid hormone receptors, it regulates gene expression involved in cellular metabolism and protein synthesis. This interaction drives downstream energetic pathways, resulting in an elevated basal metabolic rate and modulated tissue differentiation across diverse cell types. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (148.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.