CAS No. 13476-25-0

Batch: Purity:99.86
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Linderane Chemical Structure
Chemical Structure
Check the Linderane product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 13476-25-0
Molecular Formula

C15H16O4
Molecular Weight (MW) 260.29
SMILES CC1=CCCC23C(O2)C(C4=C(C1)OC=C4C)OC3=O

Biological Activity

Linderane is a natural furanosesquiterpene isolated from Lindera strychnifolia that acts as an indirect phosphodiesterase 3 (PDE3) activator. It demonstrates superoxide anion radical-scavenging and antioxidative activities, reducing intracellular reactive oxygen species. By modulating cyclic AMP signaling and inflammatory pathways, linderane protects gastrointestinal tissues against oxidative stress and gastritis in preclinical models.

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 52 mg/mL (199.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.