CAS No. 13476-25-0
Batch:
Purity:99.81
Chemical Structure
Check the
Linderane
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 13476-25-0 | |
|---|---|---|
| Molecular Formula |
C15H16O4 |
|
| Molecular Weight (MW) | 260.29 | |
| SMILES | CC1=CCCC23C(O2)C(C4=C(C1)OC=C4C)OC3=O |
Linderane is a natural furanosesquiterpene isolated from Lindera strychnifolia that acts as an indirect phosphodiesterase 3 (PDE3) activator. It demonstrates superoxide anion radical-scavenging and antioxidative activities, reducing intracellular reactive oxygen species. By modulating cyclic AMP signaling and inflammatory pathways, linderane protects gastrointestinal tissues against oxidative stress and gastritis in preclinical models.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
52 mg/mL
(199.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
52 mg/mL
(199.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.