Lidocaine hydrochloride Clinical Trials

Size	Price	Qty
100mg	USD 97
500mg	USD 297

Clinical Trials

Numerous clinical trials spanning Early Phase 1 through Phase 4 evaluate lidocaine hydrochloride across active, recruiting, and completed recruitment statuses. Predominantly sponsored by academic institutions and university medical centers, these evaluations target conditions such as procedural and labor pain, cognitive decline, axial spondyloarthritis, and surgical procedures. Collectively, this research demonstrates the drug's versatile therapeutic utility in local anesthesia, analgesia, and perioperative care.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07361549	NOT_YET_RECRUITING	Refractory Migraine; Headache	Daniel A Tonetti, MD	2026-03	PHASE2
NCT07793552	NOT_YET_RECRUITING	Vulvar Cancers; Vulva Neoplasm; Vulvar Dysplasia	Tufts Medical Center	2026-11
NCT07709390	RECRUITING	Emergency Coughing	Ohio State University	2023-05-31	EARLY_PHASE1
NCT07318285	NOT_YET_RECRUITING	Hysteroscopy / Methods; Lidocaine Infusion; Placebo - Control	YAARA TABIB	2026-02-01
NCT07631364	NOT_YET_RECRUITING	Neisseria Gonorrhoeae (Ng) Infections	Assistance Publique - Hôpitaux de Paris	2026-09	PHASE3
NCT07644923	NOT_YET_RECRUITING	Postoperative Pain	NYU Langone Health	2026-08-01	PHASE4
NCT07794878	RECRUITING	Nasolabial Folds	AbbVie	2026-08-19	PHASE3
NCT07778043	NOT_YET_RECRUITING	Myofacial Pain; Pelvic Pain	Women and Infants Hospital of Rhode Island	2026-08-17	PHASE4
NCT07687069	NOT_YET_RECRUITING	Breast Hypertrophy	Centre of Postgraduate Medical Education	2026-07
NCT07676942	NOT_YET_RECRUITING	Urethral Stricture	Centre of Postgraduate Medical Education	2026-06
NCT07414706	NOT_YET_RECRUITING	Intravenous Lidocaine; Laparoscopic Surgery; Post Operative Recovery; Local Anaesthetic Systemic Toxicity	Centre Hospitalier Universitaire, Amiens	2026-03	PHASE3
NCT07650396	RECRUITING	Achilles Tendinopathy (AT)	Erasmus Medical Center	2026-06-03	PHASE3
NCT07499154	NOT_YET_RECRUITING	Congenital Heart Disease; Postoperative Pulmonary Complications; Acute Lung Injury	The Children's Hospital of Zhejiang University School of Medicine	2026-04-01	PHASE4
NCT07268924	NOT_YET_RECRUITING	Emergence Delirium, Anesthesia	Assiut University	2026-01	PHASE4
NCT07691359	NOT_YET_RECRUITING	Osteoporotic Vertebral Fracture; Neuropathic Pain	University Hospital, Clermont-Ferrand	2026-07-01	PHASE4
NCT06304779	RECRUITING	Postoperative Pulmonary Complications; Intra-abdominal Infection	Shanghai Zhongshan Hospital	2023-10-31
NCT06792474	NOT_YET_RECRUITING	Spinal Disease; Anesthesia; Post Operative Pain	Dartmouth-Hitchcock Medical Center	2026-08	PHASE4
NCT07630155	RECRUITING	Renal Pelvis and Ureter Urothelial Carcinoma	University of Michigan Rogel Cancer Center	2026-08
NCT06146842	RECRUITING	Labor Pain	Brigham and Women's Hospital	2023-12-01	PHASE4
NCT07763132	RECRUITING	Procedural Pain	Marie Lulková	2024-09-01
NCT07294118	RECRUITING	Subarachnoid Hemorrhage, Aneurysmal; Headache; Opiate Dependence; Opioid Use	The University of Texas Medical Branch, Galveston	2026-01-02	PHASE2
NCT07432399	RECRUITING	Colon Cancer; Colorectal Cancer; Perioperative Immune Response	Institute of Oncology Ljubljana	2025-09-01	PHASE2
NCT07073846	RECRUITING	Morbid Obesity Requiring Bariatric Surgery; Postoperative Pain; Postoperative Pain Management; Postoperative Analgesia; Postoperative Adjuvant Treatment; Postoperative Inflammatory Markers; Postoperative Inflammatory Response	Instituto Mexicano del Seguro Social	2025-10-06	PHASE4
NCT06996379	RECRUITING	Evaluate Patient Comfort Level During Paracentesis by Numbing Skin With a Needle-less Device, Instead of Using a Needle to Numb the Skin	Northwestern University	2025-05-20
NCT06778460	RECRUITING	Postoperative Chronic Pain	West China Hospital	2023-05-05
NCT07602387	RECRUITING	Patients With Taxane-induced Chronic Neuropathic Pain	Hospital Ambroise Paré Paris	2024-03-12
NCT07597408	ACTIVE_NOT_RECRUITING	A Comparsion Between Articaine Hydrochloride and Buffered Lidocaine Hydrochloride	Latakia University	2025-07-15
NCT07062367	RECRUITING	Sevoflurane; Lidocaine; Propofol; Intracranial Pressure; Cerebral Oxygenation; Laparoscopic Hysterectomy	Tanta University	2025-02-01
NCT07412392	NOT_YET_RECRUITING	Nasolabial Folds, Wrinkles	Hyundae Meditech	2026-02-27
NCT06710405	RECRUITING	Pain Management After Surgery	Seoul National University Hospital	2024-12-09	PHASE4
NCT04992572	RECRUITING	Lumbar Spinal Stenosis	Stanford University	2021-12-01	EARLY_PHASE1
NCT07612839	NOT_YET_RECRUITING	Postoperative Fatigue Syndrome; Inguinal Hernia Unilateral	Hakan Emirkadı	2026-09-02
NCT07265778	ACTIVE_NOT_RECRUITING	Mid Face Volume Deficit	Jetema Co., Ltd.	2024-10-22
NCT07550348	RECRUITING	Lower Extremity; Nerve Block; Pain, Postoperative; Pain, Nerve	Ataturk University	2025-12-01
NCT06696586	NOT_YET_RECRUITING	Bier Block; Hand Surgery	Assiut University	2025-07-01	PHASE4
NCT07396129	NOT_YET_RECRUITING	Neuropathic Chronic Pain	Pontificia Universidad Catolica de Chile	2026-09-20	PHASE1; PHASE2
NCT07429292	NOT_YET_RECRUITING	Healthy Volunteers; Sympathetic Activity	Duke University	2026-09	PHASE4
NCT07699315	NOT_YET_RECRUITING	Symptomatic Irreversible Pulpitis	Watim Medical & Dental College	2026-08	PHASE4
NCT07150481	NOT_YET_RECRUITING	Enhanced Recovery After Anesthesia	Assiut University	2025-10	PHASE2; PHASE3
NCT07601698	NOT_YET_RECRUITING	Emergence Agitation	Sohag University	2026-05-01	PHASE4
NCT07488832	RECRUITING	Lumbar Fusion Surgery	Ankara City Hospital Bilkent	2026-04-01
NCT06653400	RECRUITING	Abnormal Uterine Bleeding; Analgesia; Paracervical Block	Icahn School of Medicine at Mount Sinai	2025-02-27	PHASE1
NCT06462573	UNKNOWN	Stone Ureter	Assiut University	2024-09-01	EARLY_PHASE1
NCT07572994	NOT_YET_RECRUITING	Myofacial Pain; Myofacial Pain Syndrome; Myofacial Pain Syndromes; Trigger Point Pain, Myofascial; Myofascial Pain Dysfunction Syndrome	Cairo University	2026-05-01
NCT06563050	NOT_YET_RECRUITING	Lidocaine Spray; Nebulized Lidocaine; Lung Diseases; Lung Cancer	Assiut University	2024-09
NCT07120763	RECRUITING	Distal Radius Fracture Reduction; Pain Control; Pediatric Fractures	State University of New York at Buffalo	2025-08-22	PHASE3
NCT07419815	ACTIVE_NOT_RECRUITING	Side Effects of Opoid Consumption	Shaukat Khanum Memorial Cancer Hospital & Research Centre	2025-12-03
NCT07537127	RECRUITING	Cystectomy; Myomectomy	Peking Union Medical College Hospital	2025-12-15
NCT07779356	COMPLETED	Macular Degeneration; Diabetic Retinopathy; Retinal Vein Occlusion (RVO)	Retina Consultants of Delmarva	2026-05-20	PHASE4
NCT07456826	ENROLLING_BY_INVITATION	Diabetic Macular Edema (DME); Age-Related Macular Degeneration (AMD); Retinal Vein Occlusion; Diabetic Retinopathy (DR)	Harrow Inc	2026-03-31	PHASE4
NCT07359560	NOT_YET_RECRUITING	Infertility Female; Hemodynamic Instability	Zagazig University	2026-01-02
NCT07248202	COMPLETED	Coronary Artery Disease (CAD); Left Ventricular (LV) Systolic Dysfunction; Induction Anesthesia; Coronary Bypass Graft Surgery; Ketamine; Fentanyl; Lidocaine	Cairo University	2025-12-01
NCT07511400	COMPLETED	Pain; Acute Pain; Healthy Volunteer Study	Medical University of Vienna	2026-04-21	EARLY_PHASE1
NCT06607861	COMPLETED	Pain Score (VAS)	Minia University	2024-06-01	EARLY_PHASE1
NCT06979141	RECRUITING	Cough	Al-Azhar University	2025-06-02	PHASE3
NCT06057675	RECRUITING	Postoperative Bleeding; Skin Cancer Face	Vanderbilt University Medical Center	2024-03-19	PHASE2
NCT07648784	RECRUITING	Epidural Dosage of Lidocaine Bupivacaine in Lower Limb Surgeries	Shaheed Mohtarma Benazir Bhutto Institue of Trauma	2025-12-18
NCT06865469	NOT_YET_RECRUITING	Fracture Hip Surgery	Assiut University	2025-05-01	PHASE3
NCT07047638	ACTIVE_NOT_RECRUITING	Skin Quality Improvement	Galderma R&D	2025-07-09
NCT05193227	RECRUITING	Postoperative Pain; Postsurgical Pain	University of British Columbia	2021-10-27	PHASE2
NCT07383571	COMPLETED	Hysterosalpingography	Cairo University	2025-10-03
NCT07657897	RECRUITING	Hepato Cellular Carcinoma (HCC); Sedation and Analgesia; Ablation Techniques	Iuliu Hatieganu University of Medicine and Pharmacy	2024-11-12
NCT06936410	COMPLETED	Tourniquet Hypertension	Cairo University	2025-03-01	PHASE2
NCT07162610	COMPLETED	Mid-face Volume Deficit	PharmaResearch Co.,Ltd	2024-04-07
NCT07715331	COMPLETED	Excessive Gingival Display; Gingival Diseases; Gummy Smile; Esthetics, Dental	Al-Azhar University	2025-01-01
NCT06272461	RECRUITING	Colorectal (Colon or Rectal) Cancer; Inflammation	University Tunis El Manar	2023-10-01
NCT07788261	COMPLETED	Dexamethasone; Lidocaine; Scalp Incision Infiltration; Craniotomy	Assiut University	2024-12-01
NCT06882525	COMPLETED	Herpes Zoster; Neuralgia, Postherpetic	Ankara City Hospital Bilkent	2025-04-01
NCT06236126	COMPLETED	Analgesia, Obstetrical	Ohio State University	2023-11-13
NCT07000760	COMPLETED	Postoperative Pulmonary Complications (PPCs)	Jun Zhang	2025-06-06	PHASE3
NCT07491991	COMPLETED	Postoperative Pain; NEBULIZATION; Thyroid Surgery	Qianfoshan Hospital	2025-03-02	PHASE4
NCT05289804	COMPLETED	Mild Cognitive Impairment; Memory Impairment; Memory Disorders in Old Age	University of Dublin, Trinity College	2022-09-01	PHASE1; PHASE2
NCT07212192	NOT_YET_RECRUITING	Pregnancy	Phenikaa University	2025-11-24	PHASE3
NCT07000058	ACTIVE_NOT_RECRUITING	Hand Surgery; Local Infiltration	Misr University for Science and Technology	2025-06-20	PHASE2; PHASE3
NCT03699995	TERMINATED	Cutaneous Melanoma; Melanocytic Nevus; Skin Carcinoma	OHSU Knight Cancer Institute	2018-05-18
NCT07256834	NOT_YET_RECRUITING	Post Operative Sore Throat at 6hrs and 24hrs After Endotracheal Intubation	Jinnah Postgraduate Medical Centre	2025-11-22	PHASE1; PHASE2
NCT07067853	COMPLETED	Migraine	Indonesia University	2025-09-01
NCT04084548	ACTIVE_NOT_RECRUITING	Postoperative Pain	The Cleveland Clinic	2019-10-15	PHASE3
NCT07688031	COMPLETED	Pain Management; Hemorrhoids Third Degree; Hemorrhoids Fourth Degree; Hemorrhoids Second Degree	Pontificia Universidad Catolica de Chile	2023-05-24	PHASE4
NCT06595017	NOT_YET_RECRUITING	Myofascial Pain Dysfunction Syndrome	Misr University for Science and Technology	2024-10-01	PHASE2
NCT07533643	COMPLETED	Hemodynamics After Endotracheal Intubation	Kasr El Aini Hospital	2025-08-01
NCT03095404	WITHDRAWN	Bariatric Surgery Candidate; Bariatric Bowel Surgery	McMaster University	2022-10-05	EARLY_PHASE1
NCT07092046	COMPLETED	Minimal Flow Anesthesia; General Anaesthesia; Inhalation Anesthesia; Infection Risk; Anesthesia Circuit; Microbial Colonization; Anesthesia Equipment Bacterial Contamination	Ankara City Hospital Bilkent	2025-08-01
NCT07268495	RECRUITING	Postoperative Pain	General Hospital of Ningxia Medical University	2024-08-01
NCT06552351	NOT_YET_RECRUITING	Anesthesia	University of Oklahoma	2024-11
NCT07035301	COMPLETED	Disease of Respiratory System	Harbin Medical University	2025-03-17
NCT06966102	NOT_YET_RECRUITING	Enhanced Recovery; Functional Endoscopic Sinus Surgery; Lidocaine; Magnesium Sulphate; Perioperative Pain	Cairo University	2025-05-10	PHASE4
NCT05854082	COMPLETED	Reading Disorders	University of Alberta	2023-08-24	PHASE4
NCT05058677	COMPLETED	Traumatic Brain Injury	The University of Texas Health Science Center, Houston	2021-11-09	PHASE4
NCT05153785	COMPLETED	Liver Metastases; Liver Cancer; Postoperative Pain; Opioid Use	Lund University Hospital	2021-11-15	PHASE2; PHASE3
NCT07462988	COMPLETED	Neck Pain; Mesotherapy	Istanbul Medeniyet University	2025-01-01
NCT06462781	COMPLETED	Refractory Migraine	The Cooper Health System	2024-03-15	PHASE1
NCT05161468	TERMINATED	Acromioclavicular Sprain	Brooke Army Medical Center	2021-08-12	PHASE4
NCT06640946	COMPLETED	Pilonidal Disease	David Mooney	2024-11-01	PHASE4
NCT07138586	COMPLETED	Traumatic Ulcer of Oral Mucosa	National Research Centre, Egypt	2025-01-24
NCT06570096	COMPLETED	Premixed; Sequential; Lidocaine; Bupivacaine; Supraclavicular Brachial Plexus Block; Arteriovenous Fistula	Tanta University	2024-08-24
NCT06302257	UNKNOWN	Labor Pain	Hadassah Medical Organization	2024-03-01	PHASE4
NCT06423456	COMPLETED	Postoperative Pain; Postoperative Nausea; Analgesia	Afyonkarahisar Health Sciences University	2024-03-01
NCT06040840	COMPLETED	Carpal Tunnel Syndrome	CMC Ambroise Paré	2024-05-13
NCT05920980	COMPLETED	Colorectal Cancer	West China Hospital	2023-06-05
NCT05788393	COMPLETED	Analgesia	Assiut University	2024-04-01	PHASE4
NCT03893318	TERMINATED	Systemic Lidocaine Improves Pain Control After Surgery by Attenuating the Systemic Inflammatory Response to Surgery	Washington University School of Medicine	2019-07-30	PHASE4
NCT06497296	UNKNOWN	Blood Pressure; Tachycardia	National Cheng-Kung University Hospital	2023-01-01
NCT06662318	COMPLETED	Pain, Postoperative	Benha University	2024-10-01
NCT06918340	ACTIVE_NOT_RECRUITING	Blood Gas Analysis; Topical Analgesia	Haydarpasa Numune Training and Research Hospital	2024-11-01	PHASE4
NCT06312254	COMPLETED	Peripheral Neuropathy	Aalborg University	2024-04-09
NCT06370195	UNKNOWN	Parkinson's Syndrome	Babujinaya Cela	2024-04
NCT03410836	UNKNOWN	Intravenous Lidocaine and Immunity	Ciusss de L'Est de l'Île de Montréal	2019-04-29	PHASE4
NCT07433231	COMPLETED	Anesthesia Emergence Delirium; Adenotonsillar Hypertrophy	Ayfer Kaya Gök	2023-11-01
NCT06078241	COMPLETED	Postoperative Analgesia	Ain Shams University	2023-11-01
NCT06381622	COMPLETED	Nerve Block; Anesthesia, Local; Forearm Fracture; Surgery; Brachial Plexus Block	Nordsjaellands Hospital	2024-04-18	PHASE3
NCT05031078	COMPLETED	HPV	Emory University	2021-12-21	PHASE4
NCT05614609	COMPLETED	Postoperative Complications; Intubation; Difficult or Failed; Intubation Complication	Ostfold University College	2023-03-01
NCT04781673	ACTIVE_NOT_RECRUITING	Rib Fractures; Rib Fracture Multiple; Rib Trauma	Brittany Hoyte	2021-04-01	PHASE4
NCT06443255	COMPLETED	Analgesia	Rigshospitalet, Denmark	2024-07-01	PHASE3
NCT06834854	COMPLETED	Measure Time to First Rescue Analgesia Following Extubation	Ain Shams University	2024-03-12	PHASE1
NCT06864078	COMPLETED	IUD	Al-Azhar University	2023-09-10
NCT04144933	UNKNOWN	Anesthesia; General Anesthesia; Analgesics, Opioid; Opioid Free Anesthesia; Postoperative Ileus; Colorectal Surgery; Laparoscopic Surgery; Analgesia; Dexmedetomidine; Lidocaine; Ketamine	University of Saskatchewan	2021-05-15	PHASE3
NCT05670236	COMPLETED	Osteoarthritis, Knee	The Cleveland Clinic	2023-01-25	PHASE4
NCT05017246	TERMINATED	Cancer Debulking; Enlarged Uterus; Fibroid Uterus; Adnexal Mass	Washington University School of Medicine	2022-01-18	PHASE2
NCT05313256	COMPLETED	Obstetric Labor Complications	University Hospital, Bordeaux	2022-07-14	PHASE2; PHASE3
NCT06527651	COMPLETED	Osteoarthritis; Osteoarthritis, Knee; Proprioceptive Disorders; Balance; Distorted	Ankara City Hospital Bilkent	2024-06-01
NCT05578885	UNKNOWN	Regional Anesthesia	Michael Bishay Shehata Keroles	2024-02-01
NCT05560035	UNKNOWN	Cervical Cancer; Metastatic Cancer	General Hospital of Ningxia Medical University	2022-12-01
NCT06420388	UNKNOWN	Surgery; Pain, Postoperative	E-DA Hospital	2023-05-01
NCT05072236	COMPLETED	Lung Diseases; Total Intravenous Anesthesia; Bronchoscopic Interventions	National Taiwan University Hospital	2022-05-09
NCT06457100	UNKNOWN	Chronic Rhinosinusitis; Enhanced Recovery After Surgery	The Second People's Hospital of Huai'an	2023-11-21	PHASE1; PHASE2
NCT06304116	UNKNOWN	Traumatic Brain Injury	Muhammad	2024-03
NCT06344637	UNKNOWN	Pain, Procedural; Lidocaine; Obstetric Surgical Procedures	UdonThani Hospital	2023-12-14
NCT06226415	COMPLETED	Cerebral Small Vessel Diseases	Zeng Changhao	2024-01-20
NCT06006026	UNKNOWN	Colorectal Cancer	West China Hospital	2023-08-28
NCT04069169	COMPLETED	Scoliosis; Adolescence; Anesthesia Recovery Period	University of British Columbia	2019-12-18	PHASE3
NCT06249490	UNKNOWN	Obstructive Sleep Apnea	Zeng Changhao	2024-02-29
NCT06266481	UNKNOWN	Postoperative Sore Throat	Pharos University in Alexandria	2024-03-01	PHASE2; PHASE3
NCT06225076	WITHDRAWN	Bulbar Palsy	Zeng Changhao	2024-01-30
NCT05783219	COMPLETED	Overactive Bladder; Urge Incontinence; Fecal Incontinence	University of Louisville	2023-05-01	PHASE2
NCT05800834	UNKNOWN	Wounds and Injuries; Cancer Pain; Cancer, Breast; Cancer Head Neck	Instituto Nacional de Cancer, Brazil	2023-09-12	PHASE2
NCT05707169	UNKNOWN	Varicose Veins; Venous Reflux; Venous Insufficiency; Venous Leg Ulcer	Mansoura University	2023-01-04
NCT05243940	UNKNOWN	Pain, Post Operative; Pain, Acute; Pain, Chronic; Pain, Neuropathic; Pain, Nociceptive; Ketamine; Dexmedetomidine; Lidocaine; Fentanyl; Analgesia; Analgesics; Analgesics Non-narcotic	Aretaieion University Hospital	2022-03-07
NCT06184958	UNKNOWN	Anesthesia	Ain Shams University	2023-09-02	PHASE4
NCT06383845	COMPLETED	Breast Surgery	University Tunis El Manar	2023-01-01
NCT05368753	COMPLETED	Abdominal Surgery by Laparotomy; Thoracic Epidural Analgesia; Analgesia; Lidocaine Adverse Reaction	Centre Hospitalier Universitaire, Amiens	2022-03-09	PHASE4
NCT04162535	UNKNOWN	Colorectal Cancer	Iuliu Hatieganu University of Medicine and Pharmacy	2018-11-26	PHASE1
NCT04359017	WITHDRAWN	Radius Fracture Distal; Hematoma; Lidocaine; Pediatrics	Washington University School of Medicine	2020-11-01	PHASE4
NCT04051203	COMPLETED	Occipital Neuralgia; Headache	University of Calgary	2019-02-01	PHASE1
NCT04891419	COMPLETED	Temple Hollowing	Allergan	2021-07-20	PHASE3
NCT05777759	COMPLETED	Chin Augmentation; Chin Retrusion	Galderma R&D	2023-03-22
NCT04640896	COMPLETED	Myofacial Pain; Pain, Neck; Pain, Back; Cervical Fusion	George Washington University	2020-11-05	PHASE4
NCT05937282	UNKNOWN	Hemodynamic Responses; Laparoscopic Cholecystectomy; Dexmedetomidine; Lidocaine; Propofol	Menoufia University	2023-07-01	PHASE4
NCT05850468	UNKNOWN	Opioid Use; Spine Fusion	Ain Shams University	2023-05
NCT05646810	UNKNOWN	Spinal Cord Injuries; Spinal Cord Diseases; Syringomyelia	University of Aarhus	2022-12-01
NCT06128109	COMPLETED	Mid Face Volume Deficit	Croma-Pharma GmbH	2023-01-24
NCT05822063	UNKNOWN	Arteriovenous Graft Site Pain	Ain Shams University	2023-07-25	PHASE3
NCT06003933	COMPLETED	Post Operative Pain; Cervical Spine Instability	Yasser S Mostafa, MD	2023-03-03
NCT05378113	TERMINATED	Injection Site Irritation	Emory University	2023-05-18	PHASE2
NCT05653401	COMPLETED	Renal Colic	University of Monastir	2022-11-20	PHASE2
NCT05767749	COMPLETED	Anesthetics, Local	Weill Medical College of Cornell University	2023-03-14	PHASE4
NCT05767827	COMPLETED	Local Anesthesia Adjuvants; Upper Extremity Fracture; Brachial Plexus Block	Nepal Medical College and Teaching Hospital	2023-02-01
NCT05866653	UNKNOWN	Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients	Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh	2023-03-25	PHASE2
NCT05089526	UNKNOWN	Pain, Postoperative; Pain, Acute; Pain, Chronic; Cholecystectomy; Ketamine; Dexmedetomidine; Lidocaine; Central Nervous System Depressants; Analgesia; Analgesics; Analgesic Non-narcotic	Aretaieion University Hospital	2021-10-11
NCT05801172	COMPLETED	Pain; Hysteroscopic Surgery	Jagiellonian University	2022-07-01
NCT04467125	UNKNOWN	Contraception	Augusta University	2020-01-06	PHASE4
NCT03046017	UNKNOWN	Chronic Low Back Pain	Massachusetts General Hospital	2017-08-30
NCT05909462	COMPLETED	Adhesive Capsulitis	Hitit University	2023-01-21
NCT06293807	COMPLETED	Periodontal Diseases	The University of Texas Health Science Center at San Antonio	2022-06-06	EARLY_PHASE1
NCT05793905	COMPLETED	Local Anesthesia	Damascus University	2022-12-01	PHASE4
NCT06703437	ACTIVE_NOT_RECRUITING	Prostate Cancer	Icahn School of Medicine at Mount Sinai	2022-12-13	PHASE1
NCT07155785	COMPLETED	Intrauterine Device Migration; Pain	Kanuni Sultan Suleyman Training and Research Hospital	2022-07-01
NCT05098457	WITHDRAWN	Cheek Wrinkles; Midface Contour Deficiencies	Galderma R&D	2022-02-22
NCT03872700	COMPLETED	Abscess	Montefiore Medical Center	2019-08-01	PHASE3
NCT03413371	COMPLETED	Vitreoretinal Surgeries; Postoperative Nausea and Vomiting; Postoperative Pain; Oculocardiac Reflex	Medical University of Silesia	2018-04-26
NCT05235256	UNKNOWN	Post-Dural Puncture Headache	Ain Shams University	2022-01-10
NCT05573191	UNKNOWN	General Anesthesia	General Hospital of Ningxia Medical University	2022-10-08	PHASE1; PHASE2
NCT05077488	COMPLETED	Marionette Lines Forehead Contouring	Allergan	2021-09-15	PHASE4
NCT04583137	UNKNOWN	Anesthesia, Local	Kfir Siag	2020-11-01	EARLY_PHASE1
NCT05412576	COMPLETED	Colorectal Cancer	West China Hospital	2021-06-01
NCT06082245	COMPLETED	Analgesia; Spine Fusion	Hanoi Medical University	2021-10-01
NCT04167176	COMPLETED	Postoperative Pain	Assiut University	2020-09-15
NCT04591353	COMPLETED	Total Hip Arthroplasty	University of Alabama at Birmingham	2021-02-01	PHASE3
NCT04017013	COMPLETED	Pain, Postoperative; Opioid Use	Universidad de Antioquia	2020-03-01	PHASE4
NCT05063578	UNKNOWN	Anesthesia	Far Eastern Memorial Hospital	2021-09-20
NCT03677817	COMPLETED	Postoperative Pain	University Hospital, Basel, Switzerland	2019-04-03	PHASE3
NCT04570293	COMPLETED	Trigeminal Neuralgia	Beijing Tiantan Hospital	2021-05-01	PHASE4
NCT05239091	COMPLETED	Myofascial Pain Syndrome of Neck	Istanbul Physical Medicine Rehabilitation Training and Research Hospital	2022-08-01
NCT05291221	COMPLETED	Postoperative Complications	Minia University	2021-02-22
NCT04691726	COMPLETED	Abdominal Aorta Aneurysm; Abdominal Aorta Atheroma; Surgery; Pain, Postoperative	Łukasz Krzych	2019-01-29	PHASE4
NCT04991597	WITHDRAWN	Pain	Nicholas Bastidas	2022-01-01
NCT04295330	COMPLETED	Primary Liver Cancer	West China Hospital	2020-02-27
NCT05369650	UNKNOWN	Liver Cancer	West China Hospital	2019-07-27
NCT05087732	COMPLETED	Aging	Laboratoires Vivacy	2021-10-19
NCT04822597	COMPLETED	Breast Cancer; Sentinel Lymph Node; Breast Neoplasms; Breast Cancer Female	University of Wisconsin, Madison	2021-04-23	PHASE3
NCT04216017	COMPLETED	Humeral Fractures	University of Washington	2020-01-01	PHASE2
NCT04609865	TERMINATED	Acute Respiratory Distress Syndrome (ARDS); COVID-19; Corona Virus Infection	University Hospital, Strasbourg, France	2020-11-04	PHASE3
NCT05253508	UNKNOWN	Sensory Processing; Perception; Sense of Touch; Taction	Reinier Haga Orthopedisch Centrum	2022-01-01
NCT06637046	COMPLETED	Drop Foot	Stephen Barrett	2020-03-15
NCT03071601	COMPLETED	Pain, Acute; Laceration	Centre Hospitalier le Mans	2017-12-01	PHASE4
NCT03047070	COMPLETED	Intraoperative Bleeding	Assiut University	2017-02-09	PHASE2
NCT04773093	UNKNOWN	Craniotomy Tumor Removal Surgery	Indonesia University	2021-01-01	PHASE1; PHASE2
NCT04055116	COMPLETED	Pediatric Dentistry	Geisinger Clinic	2019-11-11	PHASE4
NCT04282239	WITHDRAWN	Pain, Postoperative; Cardiac Surgery	NYU Langone Health	2021-03-01
NCT04634656	UNKNOWN	Cognitive Dysfunction, Postoperative	Assiut University	2021-01-07	PHASE2
NCT02647892	TERMINATED	Local Anesthesia	University of Nebraska	2016-01-08	PHASE4
NCT04813614	COMPLETED	Esthetics	Laboratoires Vivacy	2021-05-31
NCT04535089	COMPLETED	Analgesia	Zagazig University	2020-10-01	PHASE1; PHASE2
NCT04364425	UNKNOWN	Adhesive Capsulitis	Taipei Veterans General Hospital, Taiwan	2020-05-04
NCT04517890	UNKNOWN	IUCD Complication	Aswan University Hospital	2020-09-01
NCT05361291	COMPLETED	Pulpitis - Irreversible	Jamia Millia Islamia	2020-02-01
NCT04455711	UNKNOWN	Cough; Lidocaine	Ajou University School of Medicine	2020-07-01
NCT04003012	COMPLETED	Leukemia-Lymphoma	CAMC Health System	2019-07-19	PHASE4
NCT04438577	UNKNOWN	Breast Cancer	Shantou Central Hospital	2020-08-20
NCT03821545	COMPLETED	Colorectal Cancer	University Hospital Dubrava	2019-01-28
NCT04836819	COMPLETED	Morbid Obesity; Bariatric Surgery Candidate; Pain; Postoperative	Ondokuz Mayıs University	2021-04-08
NCT04733781	UNKNOWN	Venomous Snakebites; Local Anesthesia; Painless Injection; Regional Anesthesia; Dermatologic Surgery; Cutaneous Pain; Musculoskeletal Pain	Jeffrey Alan Klein, MD	2021-02-22	PHASE2; PHASE3
NCT04033562	TERMINATED	Opioid-use Disorder; Opioid Use; Opioid Dependence; Opioid Abuse; Medication Assisted Treatment; Infusion Catheter, Wound; Lidopatch; Ambu ACTion; Pregnancy Related; Cesarean Section	WellSpan Health	2020-01-15	PHASE4
NCT04369950	COMPLETED	Physiological Effect of Drugs; Morphine; Analgesics; Analgesics, Opioid; Central Nervous System Depressants; Narcotics	The University of Texas Health Science Center, Houston	2020-05-11	PHASE4
NCT06056947	COMPLETED	Trichomonal Vaginitis; Bacterial Vaginosis; Candidal Vulvovaginitis; Mixed Vaginal Infections	Ege University	2020-07-20	PHASE3
NCT03171987	COMPLETED	Acute Back Pain	Taipei Medical University Hospital	2017-06-14	PHASE4
NCT07259772	ACTIVE_NOT_RECRUITING	End Stage Renal Disease (ESRD); Arteriovenous Fistula Patency; Chronic Kidney Disease 5D	The First People's Hospital of Lianyungang	2019-04-10	PHASE4
NCT03871478	UNKNOWN	Lidocaine; Bupivacaine; Mohs Surgery; Anesthetic	Ottawa Hospital Research Institute	2019-10-01
NCT03755089	UNKNOWN	Overactive Bladder Syndrome; Urge Incontinence; Urinary Incontinence; Detrusor Hyperreflexia; Detrusor Instability	Women and Infants Hospital of Rhode Island	2018-11-01	PHASE4
NCT04585061	COMPLETED	Anxiety; Pain	Riyadh Elm University	2020-11-01
NCT04339348	COMPLETED	Contraception	Cairo University	2020-04-30	PHASE3
NCT04703127	UNKNOWN	Premature Ejaculation	Sohag University	2020-03-30	PHASE3
NCT07696429	COMPLETED	Laryngo-pharyngeal Reflux	Mario Bilić	2019-03-01
NCT04711668	COMPLETED	Spine Fusion; Postoperative Pain	Ataturk University	2019-05-29
NCT03571737	COMPLETED	Acute Musculoskeletal Disease; Sprains; Sprains and Strains; Injuries; Emergencies; Trauma; Acute Pain	East Carolina University	2018-06-23	PHASE3
NCT03636451	COMPLETED	Abortion, Spontaneous; Abortion in First Trimester; Pain Uterus; Abortion Early; Abortion, Missed	University of California, San Diego	2018-10-29	PHASE3
NCT04569045	COMPLETED	Dermal Filler; Hyaluronic Acid; Lidocaine; Nasolabial Fold	SciVision Biotech Inc.	2020-08-20
NCT03806595	COMPLETED	Migraine in Children; Posttraumatic Headache	University of British Columbia	2019-07-03	PHASE1
NCT04140396	TERMINATED	Rib Fractures	Stanford University	2020-02-10	PHASE4
NCT04401878	COMPLETED	Post-Dural Puncture Headache	Zagazig University	2020-05-24
NCT03731429	UNKNOWN	Lidocaine	Hospital Fernandez	2019-04-05	PHASE4
NCT04101019	UNKNOWN	Nerve Block	Rabin Medical Center	2019-09
NCT04393610	UNKNOWN	Analgesia	Assiut University	2020-05-14	PHASE2; PHASE3
NCT03829618	TERMINATED	Bronchiectasis Adult; Mediastinal Lymphadenopathy; Pneumonia; Chest--Diseases; Infiltrates; Bronchopulmonary Disease; Cancer, Lung	Milton S. Hershey Medical Center	2019-04-01	PHASE3
NCT02822144	COMPLETED	Stroke	Rennes University Hospital	2016-09-29	PHASE3
NCT07551713	COMPLETED	Healthy	Haisco Pharmaceutical Group Co., Ltd.	2020-06-11	PHASE1
NCT02924480	COMPLETED	Invasive Bladder Cancer	CAMC Health System	2016-10-12
NCT04085744	COMPLETED	Anesthesia Intubation Complication; Intubation Complication; Sore Throat	Derince Training and Research Hospital	2019-11-01
NCT03990883	COMPLETED	Dermatological Non-Disease	Croma-Pharma GmbH	2019-06-04
NCT03650387	COMPLETED	Signs of Facial Aging With Volume Loss in the Upper Cheeks, Nasolabial Folds and Marionette Lines	Merz North America, Inc.	2018-09-17
NCT04480281	COMPLETED	Lidocaine; Pain, Postoperative	Saint-Joseph University	2020-01-10	PHASE4
NCT03625076	UNKNOWN	Shoulder Dislocation	Kendall Healthcare Group, Ltd.	2018-06-01	PHASE4
NCT03382821	COMPLETED	Cervical Radiculopathy	University of Utah	2017-09-15	PHASE4
NCT04167189	COMPLETED	ADHD	PhenoSolve, LLC	2018-01-20	EARLY_PHASE1
NCT03761329	COMPLETED	Surgery; Anesthesia, Local	Jessa Hospital	2018-11-12
NCT02090998	TERMINATED	Transformed Migraine; Chronic Daily Headache	Rutgers, The State University of New Jersey	2014-05	PHASE4
NCT03754413	COMPLETED	Mid Face Volume Loss	Medy-Tox	2018-05-29
NCT02818894	TERMINATED	Total Hip Arthroplasty	Thomas L Bradbury	2016-09-27	PHASE4
NCT04069585	COMPLETED	Aging; Pain	Teoxane SA	2019-10-30
NCT03886896	COMPLETED	Acute Appendicitis; Postoperative Pain; Postoperative Nausea and Vomiting	Medical University of Warsaw	2019-03-22	PHASE4
NCT02924441	COMPLETED	Pain	The University of Texas Health Science Center at San Antonio	2016-10-01
NCT04143165	COMPLETED	Epidural Block in Axial Spondyloarthritis	Sohag University	2019-10-12	PHASE4
NCT03770208	UNKNOWN	Rib Fracture Multiple; Pain, Chest; Pain, Acute; Respiratory Failure; Thoracic Injuries; Trauma Chest	Western University, Canada	2019-06-06
NCT03805282	UNKNOWN	Cough	Brasilia University Hospital	2018-03-01	PHASE3
NCT03210038	COMPLETED	Hematuria; Dysuria; Recurrent Uti	Assaf-Harofeh Medical Center	2017-03-01
NCT04029610	COMPLETED	Evaluation of Cardiac Arrhythmias in Hand Surgery Using Local Anesthesia With Adrenaline	Uri farkash	2018-08-14
NCT03862287	UNKNOWN	Orthopedic Disorder; Leg Injuries	McGill University Health Centre/Research Institute of the McGill University Health Centre	2018-11-01
NCT04000126	COMPLETED	Pain	University of Warmia and Mazury	2019-02-25
NCT03490396	TERMINATED	Oral Mucositis	Midatech Pharma US Inc.	2018-05-15	PHASE4
NCT03661996	COMPLETED	Knee Osteoarthritis	Centrexion Therapeutics	2018-09-18	PHASE3
NCT03880409	COMPLETED	Overcoming the Failure of Anesthesia in the Mandibular Teeth	Taibah University	2019-02-09	PHASE1
NCT03030677	COMPLETED	Breastcancer; Phyllodes Breast Tumor	Kasr El Aini Hospital	2018-11-01
NCT03869450	COMPLETED	Volume Deficiency of the Midface	Galderma R&D	2018-11-09
NCT03813030	COMPLETED	Healthy; Dermal Pharmacokinetic Measurement	Joanneum Research Forschungsgesellschaft mbH	2019-01-16
NCT02649322	COMPLETED	Knee Injury	Orlando Health, Inc.	2015-09-03
NCT04040309	COMPLETED	Myofascial Pain	Lithuanian University of Health Sciences	2019-05-10	PHASE4
NCT03839134	COMPLETED	Anesthetics, Local	Riyadh Colleges of Dentistry and Pharmacy	2019-03-20
NCT03576053	COMPLETED	Itch; Thermal Stimulation; Histamine; Cowhage; Serotonine	Aalborg University	2018-07-01
NCT03865147	UNKNOWN	Wounds Injuries; Anesthesia, Local	Medical Ethics UK Ltd	2019-01-15	PHASE2
NCT03414879	COMPLETED	Anesthesia	Ain Shams University	2018-01-15	PHASE4
NCT03472469	COMPLETED	Nonspecific Pain Post Traumatic Injury	The University of Texas Health Science Center, Houston	2018-04-02	PHASE4
NCT03103100	COMPLETED	Labor Pain	University of Alabama at Birmingham	2015-10-08	PHASE3
NCT03640468	UNKNOWN	Septic Shock; Anesthesia	Cairo University	2018-12-20	PHASE3
NCT03571919	WITHDRAWN	Rib Fracture Multiple; Trauma Chest; Pain, Acute	Stanford University	2018-06-15	PHASE4
NCT02894710	COMPLETED	Carcinologic Ear, Nose, and Throat (ENT) Surgery	Hospices Civils de Lyon	2016-12	PHASE3
NCT03733275	COMPLETED	Nasal Fracture	The Catholic University of Korea	2018-12-03
NCT02315573	COMPLETED	Carpal Tunnel Syndrome	St. Mary's Research Center, Canada	2014-10
NCT03792776	UNKNOWN	Postoperative Sore Throat; Postoperative Cough	Ogarite Habib	2019-01
NCT03613974	UNKNOWN	Orthopedic Procedures	Healthpoint Hospital	2018-12-15	PHASE4
NCT03620513	COMPLETED	Throat Disorder	Lumbini Medical College	2018-09-01	PHASE4
NCT02904096	COMPLETED	Volume Loss in the Dorsum of the Hand	Merz North America, Inc.	2016-06-10
NCT03362905	UNKNOWN	IUD Insertion Complication	Ain Shams University	2017-12-03	PHASE4
NCT02930551	COMPLETED	Neuropathic Pain; Neuroma	Danish Pain Research Center	2016-09
NCT03363425	UNKNOWN	Hysterectomy; Myomectomy	University of Athens	2017-11-14	PHASE2; PHASE3
NCT02616419	COMPLETED	Child; Pain Due to Certain Specified Procedures	St. Justine's Hospital	2017-05-15
NCT03262857	COMPLETED	Local Anesthesia	Isfahan University of Medical Sciences	2016-09-21	PHASE2
NCT03220555	COMPLETED	Intravenous Injections; Vaccination	Nantes University Hospital	2017-10-04
NCT04319926	COMPLETED	Healthy	Scilex Pharmaceuticals, Inc.	2018-09-07	PHASE1
NCT03729505	COMPLETED	Morbid Obesity	Mansoura University	2017-07-01
NCT02335190	COMPLETED	Sprain of Sacroiliac Ligament; Low Back Pain; Osteoarthritis Nos, of Sacroiliac Joint	Western University, Canada	2015-09
NCT02591199	TERMINATED	Interstitial Cystitis; Bladder Pain Syndrome	Urigen	2015-09	PHASE2
NCT04214938	COMPLETED	Nasopharyngeal Diseases	Selcuk University	2016-02-01	PHASE4
NCT02875015	COMPLETED	Postoperative Pain	Atlantic Health System	2016-04
NCT03415724	UNKNOWN	Irreversible Pulpitis	Postgraduate Institute of Dental Sciences Rohtak	2018-02-01
NCT05732181	COMPLETED	Liver Cancer; Post Ablation Syndrome	National Cheng-Kung University Hospital	2017-05-09
NCT03613207	COMPLETED	Dermatology/Skin - Other; Dermal Pharmacokinetic Measurements	Joanneum Research Forschungsgesellschaft mbH	2018-03-22
NCT03953001	COMPLETED	Local Anaesthetic; Dental Anxiety	Imam Abdulrahman Bin Faisal University	2018-01-01
NCT04692896	COMPLETED	Lidocaine	King Edward Medical University	2017-09-01	PHASE1
NCT03097783	COMPLETED	Midface Volume Deficit	Galderma R&D	2017-04-26
NCT03264586	UNKNOWN	Episiotomy Pain	Cairo University	2017-08	PHASE4
NCT01836614	WITHDRAWN	Colorectal Disorders	Children's Hospital Medical Center, Cincinnati	2015-01	PHASE1; PHASE2
NCT03127384	COMPLETED	Healthy Volunteers	Galderma R&D	2017-04-20	PHASE4
NCT03321825	COMPLETED	Moderate to Severe Midface Volume Deficit	Merz North America, Inc.	2017-09-29
NCT02995083	WITHDRAWN	Symptomatic Osteoarthritis of the Knee	Rush University Medical Center	2017-06	EARLY_PHASE1
NCT03041506	UNKNOWN	Shoulder Dislocation; Brachial Plexus Block	Tel-Aviv Sourasky Medical Center	2017-02-15
NCT03159000	WITHDRAWN	Migraine	Thomas Jefferson University	2017-05-01	PHASE4
NCT02747186	COMPLETED	Anesthesia	University of North Carolina, Chapel Hill	2016-05
NCT02726620	COMPLETED	Hypotension	Vanderbilt University Medical Center	2017-01-05
NCT02787356	WITHDRAWN	Skin Manifestations	SRI International	2017-10-01
NCT01145326	WITHDRAWN	Pain Perception; Phlebotomy	University of Oklahoma	2015-01	PHASE2; PHASE3
NCT02229578	COMPLETED	Pain	University of Florida	2014-09	PHASE4
NCT03731988	COMPLETED	Actinic Keratosis	Dong-A University	2017-02-01	PHASE4
NCT02741232	COMPLETED	Nerve Block; Mastectomy	Maisonneuve-Rosemont Hospital	2016-03
NCT02620683	COMPLETED	Blood Levels of Buffered vs Non-buffered Lidocaine; Anesthetics, Local	University of North Carolina, Chapel Hill	2015-12
NCT02991040	COMPLETED	Nasolabial Fold Correction	Prollenium Medical Technologies Inc.	2016-08
NCT04064047	COMPLETED	Pain; Prostate Cancer; Rectal/Anal	Assaf-Harofeh Medical Center	2016-12
NCT02592629	TERMINATED	Shoulder Pain	Milton S. Hershey Medical Center	2016-02-01	PHASE4
NCT02558283	COMPLETED	Nasolabial Fold	Allergan	2016-01-25
NCT03140787	COMPLETED	Dental Caries	Damascus University	2016-05-15
NCT03044808	COMPLETED	Opioid Use	Odense University Hospital	2016-02-02	PHASE4
NCT03063112	UNKNOWN	Abdominal Cancer	South Egypt Cancer Institute	2016-10-01
NCT02403986	COMPLETED	Aged Skin	Galderma R&D	2015-04	PHASE4
NCT02749162	COMPLETED	Postoperative Pain	Foisor Orthopedics Clinical Hospital	2015-11	PHASE3
NCT02857686	UNKNOWN	Local Anaesthesia	Cairo University	2016-10
NCT03449940	COMPLETED	Erectile Dysfunction	Ministry of Health, Jamaica	2015-01
NCT02120261	TERMINATED	Myofascial Pain Syndrome	The University of Texas Health Science Center, Houston	2014-05	PHASE4
NCT03634605	COMPLETED	Primary Spontaneous Pneumothorax	Isfahan University of Medical Sciences	2015-05-05
NCT02507440	COMPLETED	Topical Anesthesia	Bassett Healthcare	2015-09	PHASE4
NCT02228083	UNKNOWN	Heart Failure	University of Sao Paulo General Hospital	2014-09
NCT02912195	COMPLETED	Pain	Alameda Health System	2016-03	PHASE4
NCT02590705	UNKNOWN	Spinal Puncture; Anesthesia	Beijing Children's Hospital	2015-10
NCT03120923	COMPLETED	Impingement Shoulder	Ramathibodi Hospital	2015-01-01	PHASE4
NCT02567838	COMPLETED	Gynecologic Diseases	Kangbuk Samsung Hospital	2015-10	PHASE3
NCT02703948	COMPLETED	Lip Augmentation and Correction of Perioral Rhytids	Galderma R&D	2016-03
NCT02574832	TERMINATED	Pregnancy; Surgery; Pain	Northwestern University	2015-10
NCT00938964	COMPLETED	Cognitive Decline	Duke University	2009-07
NCT02684786	WITHDRAWN	Pulmonary Artery Hypertension	Mayo Clinic	2016-07	PHASE1
NCT02137954	UNKNOWN	Cancer; Pain With Neuropathic Component	Assistance Publique Hopitaux De Marseille	2014-05	PHASE3
NCT00659633	COMPLETED	Pain	University of Alabama at Birmingham	2008-12
NCT02510287	COMPLETED	Labor Pain	Fundación Santa Fe de Bogota	2015-07
NCT01503060	UNKNOWN	Pain	The Hospital for Sick Children	2011-12	PHASE3
NCT02657603	COMPLETED	Pain	Kai Henrik Wiborg Lange	2016-01
NCT01883232	WITHDRAWN	Pediatric Dentistry	University of Colorado, Denver	2013-08
NCT02447029	COMPLETED	Pregnancy, Unwanted	Stanford University	2015-04	PHASE3
NCT03189329	COMPLETED	Vitreoretinal Surgery; Cognitive Function Abnormal; Intraoperative Monitoring	Cengiz KAYA	2015-01	PHASE4
NCT03175913	COMPLETED	Low Back Pain	The Catholic University of Korea	2014-06-01
NCT02700906	COMPLETED	Tennis Elbow; Lateral Epicondylitis	Shin Kong Wu Ho-Su Memorial Hospital	2014-01
NCT02454296	COMPLETED	Pain	University of Hawaii	2015-05
NCT02241460	UNKNOWN	Premature Ejaculation	Eugene Y Rhee, MD	2014-03	PHASE3
NCT01751347	COMPLETED	Carpal Tunnel Syndrome; Trigger Finger	University of British Columbia	2013-02	PHASE4
NCT02264795	COMPLETED	Pain	Samuel Lunenfeld Research Institute, Mount Sinai Hospital	2014-11
NCT01179100	WITHDRAWN	General Anesthesia; Surgeries Requiring A Minimum One Day Hospitalization; Elderly	Cedars-Sinai Medical Center	2011-06	PHASE4
NCT02158039	COMPLETED	Neoplasms, Cystic, Mucinous, and Serous	Mayo Clinic	2004-06	PHASE1
NCT02689856	COMPLETED	Hemorrhoids	Citius Pharmaceuticals, Inc.	2015-05	PHASE2
NCT02505633	COMPLETED	Radius Fractures	Gachon University Gil Medical Center	2015-07
NCT02372786	COMPLETED	Tattoo; Acne Keloidalis Nuchae	Erasmus Medical Center	2014-11	PHASE4
NCT02332057	COMPLETED	Pain	Cairo University	2015-02	PHASE2
NCT02059694	WITHDRAWN	Upper Eyelid Surgery	Duke University
NCT03435185	COMPLETED	Migraine Disorders	Dr. Lutfi Kirdar Kartal Training and Research Hospital	2014-09-01
NCT01114997	TERMINATED	Pain; Constipation; Nausea; Vomiting	Cedars-Sinai Medical Center	2010-04	PHASE4
NCT01675947	TERMINATED	Geographic Atrophy	National Eye Institute (NEI)	2012-02	PHASE2
NCT03376178	COMPLETED	Pain	University Hospital, Geneva	2014-05
NCT02061475	UNKNOWN	We Focus on the Pain of Venipuncture and Intravenous Cannulation	RenJi Hospital	2014-04	PHASE2; PHASE3
NCT02001740	COMPLETED	Adhesive Capsulitis	Queen's University	2012-12	PHASE4
NCT01907997	COMPLETED	Thyroid Cancer	Yonsei University	2013-07
NCT02257346	WITHDRAWN	Pregnancy	Northwestern University	2014-11-01
NCT02628522	COMPLETED	Anal Fissure	Clinical Centre of Serbia	2014-12
NCT00840918	TERMINATED	Atrial Fibrillation	The Cleveland Clinic	2009-02
NCT01812044	COMPLETED	Strabismus	Duke University	2013-03
NCT02935972	COMPLETED	Pain Relief During Prostate Biopsy	Assiut University	2013-11	PHASE2; PHASE3
NCT02018276	COMPLETED	Thyroid Cancer	Yonsei University	2013-12
NCT03397082	COMPLETED	Pain	Saint Thomas Hospital, Panama	2014-08-01
NCT02059902	COMPLETED	Thermal Burns	HealthPartners Institute	2012-09	PHASE4
NCT01314300	COMPLETED	Neuropathic Pains; Vasoocclusive Sickle Cell Crises Pains	Centre Leon Berard	2011-03	PHASE2
NCT01944098	COMPLETED	Bariatric Surgical Pain	University of South Florida	2013-08	PHASE3
NCT01774292	COMPLETED	Coughing; Extubation; Lidocaine; Endotracheal Cuff	Université de Sherbrooke	2013-01	PHASE4
NCT02086292	COMPLETED	Needlestick Injuries	Norwegian University of Science and Technology	2014-02
NCT01967017	WITHDRAWN	IUD Insertion Complication; Pain Control	Johns Hopkins University	2014-06	PHASE4
NCT01537770	COMPLETED	Osteoporotic Fractures	Spine Centre of Southern Denmark	2012-02
NCT01715688	COMPLETED	Cough; Anesthesia	Centre hospitalier de l'Université de Montréal (CHUM)	2013-01
NCT01908738	COMPLETED	Endometrial Biopsy; Abnormal Uterine Bleeding	Mahidol University	2013-09
NCT02487914	COMPLETED	Interferential Current Drug Delivery	Shiraz University of Medical Sciences	2013-01	PHASE2; PHASE3
NCT00413127	TERMINATED	Elective Surgical Procedure; Colorectal Surgery	University Hospital Muenster	2007-09	PHASE2; PHASE3
NCT01544283	UNKNOWN	Shoulder Pain	Injury Care Medical Center	2012-03	PHASE2
NCT01794247	TERMINATED	Transient Neurologic Syndrome	Hospital General de Ciudad Real	2013-04	PHASE3
NCT01841294	UNKNOWN	Colorectal Cancer	Maisonneuve-Rosemont Hospital	2012-01	PHASE4
NCT01043211	WITHDRAWN	Back Pain	University of Alabama at Birmingham	2012-01
NCT01868776	COMPLETED	Irreversible Pulpitis (Toothache)	Ohio State University	2013-03
NCT01463280	COMPLETED	Postoperative Thromboembolism	Klein, Jeffrey A., M.D.	2011-01	PHASE1
NCT02109510	COMPLETED	Primary Spontaneous Pneumothorax	Korea University	2012-11
NCT01394250	COMPLETED	Pain; Anxiety	Children's Hospital of Philadelphia	2011-06	PHASE2
NCT05342870	COMPLETED	Bier Block; Dexmedetomidine; Tourniquet Pain; Carpal Tunnel; Tendon Release; Tendn Transfer	American University of Beirut Medical Center	2012-08
NCT02020551	COMPLETED	Pain	Kayseri Education and Research Hospital	2013-05
NCT02007408	COMPLETED	Pain Score	Kayseri Education and Research Hospital	2013-05
NCT01759459	COMPLETED	Pain; Local Anesthesia for Peripheral Intravenous Catheterization	Allina Health System	2013-01	PHASE4
NCT00826462	COMPLETED	Tennis Elbow; Epicondylitis, Lateral Humeral	University of Oslo	2009-03	PHASE4
NCT01069354	COMPLETED	Nasolabial Folds	Merz North America, Inc.	2012-11
NCT00747669	SUSPENDED	Pain	ZARS Pharma Inc.	2008-09	PHASE4
NCT01157546	TERMINATED	Opioid Consumption; Incidence of Nausea and Vomiting; Postoperative Pain; Assessment of Recovery	McGill University Health Centre/Research Institute of the McGill University Health Centre	2010-08	PHASE1
NCT01292447	COMPLETED	Pain	Women and Infants Hospital of Rhode Island	2011-02
NCT01688648	COMPLETED	Unstable Angina; Coronary Artery Bypass Graft; Dexmedetomidine; Lidocaine; Myocardial Injury; Arrhythmia; Blood Electrolyte Balance	Samsung Medical Center	2012-09
NCT01794533	COMPLETED	Painful Irreversible Pulpitis	Islamic Azad University, Sanandaj	2012-10	PHASE2
NCT02387567	COMPLETED	Chronic Low Back Pain	Marta Imamura	2007-01	PHASE3
NCT02025361	COMPLETED	Adenocarcinoma of Prostate	Bagcilar Training and Research Hospital	2009-02	PHASE4
NCT01756443	COMPLETED	Open Reduction Internal Fixation(ORIF) of Lateral Malleolus	Cork University Hospital	2011-08	PHASE4
NCT01155986	TERMINATED	Pain; Chronic Pain; Neuropathic Pain; Postoperative Pain	Grünenthal GmbH	2010-08	PHASE2
NCT01451840	COMPLETED	Cough; Anesthesia	Centre hospitalier de l'Université de Montréal (CHUM)	2012-01
NCT01405768	COMPLETED	Uterine Cervical Dysplasia	Washington University School of Medicine	2011-07	PHASE2
NCT01576770	UNKNOWN	Pain on Propofol IV Injection	The University of Texas Health Science Center, Houston	2012-04	PHASE4
NCT01192490	UNKNOWN	Contraception	University of Tennessee	2010-08
NCT01832675	COMPLETED	Application Site Discomfort	Ove Andersen	2012-03	PHASE2
NCT02102620	COMPLETED	Hands Osteoarthritis	Federal University of São Paulo	2011-08	PHASE4
NCT01045694	TERMINATED	Arthritis Multiple Joint	University of Missouri-Columbia	2011-03	PHASE4
NCT01443325	COMPLETED	Inguinal Pain	Rigshospitalet, Denmark	2011-09	PHASE3
NCT01548794	COMPLETED	Anesthesia; Inguinal Hernia	Diskapi Teaching and Research Hospital	2012-03	PHASE4
NCT02150031	COMPLETED	Bacteremia; Tooth Extraction Status Nos	University of Santiago de Compostela	2010-12	PHASE4
NCT01612156	COMPLETED	Pelvic Floor Disorders	University of Southern California	2011-12
NCT01485939	UNKNOWN	Postoperative, Pain	Seoul National University Hospital	2011-11	PHASE4
NCT00657358	COMPLETED	Pain	University of Alabama at Birmingham	2008-04
NCT01291979	UNKNOWN	Postoperative Pain	Chung-Ang University Hospital	2011-02	PHASE4
NCT01411995	COMPLETED	Pain	Washington University School of Medicine	2011-08
NCT01496105	UNKNOWN	Drug Usage	Ain Shams University	2011-07	PHASE4
NCT01360749	COMPLETED	Local Anesthesia	ISDIN	2011-05	PHASE2
NCT01155440	COMPLETED	Colon Cancer; Inflammatory Bowel Diseases; Diverticulitis	McGill University Health Centre/Research Institute of the McGill University Health Centre	2009-06	PHASE2
NCT02696460	COMPLETED	Chronic Leg Ulcer	Venenklinik Bellevue	2010-04
NCT00913003	TERMINATED	Pain	Northwestern University	2009-05	PHASE4
NCT00808171	COMPLETED	Leukemia; Non Hodgkin Lymphoma	Federal University of Minas Gerais	2009-02	PHASE4
NCT01041872	COMPLETED	General Anesthesia	Hopital Foch	2009-12	PHASE4
NCT01675895	COMPLETED	Benign Prostate Hyperplasia	Diskapi Teaching and Research Hospital	2009-07	PHASE4
NCT01373593	TERMINATED	Pain	Rigshospitalet, Denmark	2011-01	PHASE4
NCT02162680	COMPLETED	IV Insertion Pain	Duke University	2010-03	PHASE4
NCT01620112	COMPLETED	Fascicular Block; Motor Activity; Pain, Postoperative; Latency Period	Universidade Federal do Rio de Janeiro	2009-02	PHASE2
NCT01198834	COMPLETED	Ankle Sprains	MEDRx USA, Inc.	2010-09	PHASE3
NCT01252225	COMPLETED	Chronic Cough	Manchester University NHS Foundation Trust	2011-02	PHASE4
NCT01112748	COMPLETED	Neuropathic Pain	Danish Pain Research Center	2010-04	PHASE4
NCT03120351	COMPLETED	Perioperative Chest Pain	The Cleveland Clinic	2009-09
NCT00789620	COMPLETED	Pain; Fatigue	Insel Gruppe AG, University Hospital Bern	2008-11	PHASE3
NCT00851513	COMPLETED	Pudendal Neuralgia; Canal Syndrome	Nantes University Hospital	2008-11	PHASE4
NCT01542125	COMPLETED	Pain	University of Alberta	2008-09	PHASE4
NCT00786916	COMPLETED	Pain	Akron Children's Hospital	2008-02	PHASE4
NCT00804609	COMPLETED	Epidural Analgesia, Obstetric	Stanford University	2008-09
NCT01184105	COMPLETED	Premature Ejaculation	Plethora Solutions Ltd	2010-09	PHASE1
NCT01912755	COMPLETED	Irreversible Pulpitis; Pain	University of Campinas, Brazil	2010-02	PHASE4
NCT00540982	COMPLETED	Lung Cancer; Unspecified Adult Solid Tumor, Protocol Specific	City of Hope Medical Center	1997-02-20	PHASE1; PHASE2
NCT00991068	COMPLETED	Carpal Tunnel Syndrome	ZARS Pharma Inc.	2009-09	PHASE2
NCT01106716	COMPLETED	Postherpetic Neuralgia	KAI Pharmaceuticals	2009-03	PHASE2
NCT01023334	COMPLETED	Cataract	Wenzhou Medical University	2009-12
NCT00903825	COMPLETED	Local Anesthetics; Ultrasound Guidance; Catheterization	University of Patras	2009-01	PHASE2; PHASE3
NCT03713762	COMPLETED	Anesthesia, Local	Centro Medico Docente la Trinidad	2009-10-01	PHASE3
NCT00791024	COMPLETED	Analgesia	Ove Andersen	2008-11	PHASE1; PHASE2
NCT01006187	COMPLETED	Pain; Anxiety	The Hospital for Sick Children	2009-10	PHASE3
NCT00848679	WITHDRAWN	Pre-eclampsia	Hadassah Medical Organization	2009-03	PHASE3
NCT01300754	COMPLETED	Osgood-Schlatter Disease	Universidad Nacional de Rosario	2006-01	PHASE1; PHASE2
NCT00798083	COMPLETED	Neuropathic Pain Secondary to Radiation Therapy	British Columbia Cancer Agency	2008-04	PHASE3
NCT00822419	UNKNOWN	Sternotomy	Tel-Aviv Sourasky Medical Center	2009-02	PHASE4
NCT00822133	UNKNOWN	Postoperative Pain	Tel-Aviv Sourasky Medical Center	2009-02	PHASE4
NCT00864682	COMPLETED	Pain	Benaroya Research Institute	2008-01	PHASE4
NCT00588354	TERMINATED	Lumbar and Other Intervertebral Disc Disorders With Radiculopathy	Mayo Clinic	2006-10
NCT00798018	COMPLETED	Pharyngitis	Sichuan University	2008-10
NCT00686231	COMPLETED	Healthy	University of California, San Francisco	2008-05	PHASE1
NCT01425840	COMPLETED	Anesthesia	University of Campinas, Brazil	2008-03	PHASE1
NCT00487084	COMPLETED	Labor; Analgesia, Epidural	Northwestern University	2004-08
NCT00763880	TERMINATED	Forearm Fracture	Rhode Island Hospital	2005-11	PHASE4
NCT00716443	TERMINATED	Nasolabial Folds	Galderma R&D	2008-07	PHASE4
NCT01108562	WITHDRAWN	Postoperative Pain Management After Total Hip Arthroplasty	Loma Linda University	2008-02	PHASE1; PHASE2
NCT00653861	COMPLETED	Nasolabial Folds	Allergan Medical	2008-04
NCT00596050	COMPLETED	Conscious Sedation Failure During Procedure	Drexel University College of Medicine	2006-08	PHASE4
NCT00589979	COMPLETED	Osteoarthritis of the Knee	Endo USA Inc., a Keenova Therapeutics Company	2007-03	PHASE2
NCT02287870	COMPLETED	Anesthesia	Jinling Hospital, China	2008-01	PHASE4
NCT00811187	COMPLETED	Paracervical Block	Montefiore Medical Center	2007-03	PHASE2
NCT02218203	COMPLETED	Central Neuropathic Pain; Allodynia; Spinal Cord Injury	Brigham and Women's Hospital	2003-04	PHASE2
NCT01439399	COMPLETED	Postoperative Pain	University of Lausanne Hospitals	2005-12
NCT00236249	COMPLETED	Colorectal Neoplasms	Assistance Publique - Hôpitaux de Paris	2005-05	PHASE3
NCT00058357	COMPLETED	Pain; Unspecified Adult Solid Tumor, Protocol Specific	Alliance for Clinical Trials in Oncology	2004-05	PHASE3
NCT00600158	COMPLETED	Postoperative Ileus	University of Virginia	2005-04	PHASE3
NCT00740285	COMPLETED	Scleroderma	Federal University of São Paulo	2004-04	PHASE2; PHASE3
NCT03765697	COMPLETED	Post Herpetic Neuralgia	Grünenthal GmbH	2003-07-16	PHASE3
NCT00110253	COMPLETED	Pain	ZARS Pharma Inc.	2005-06	PHASE3
NCT00904605	TERMINATED	Osteoarthritis of the Knee	Endo USA Inc., a Keenova Therapeutics Company	2004-06	PHASE4
NCT03745404	COMPLETED	Post Herpetic Neuralgia	Grünenthal GmbH	2003-04-29	PHASE3
NCT00903851	COMPLETED	Diabetes	Endo USA Inc., a Keenova Therapeutics Company	2002-04	PHASE4
NCT00142064	COMPLETED	Urinary Tract Infection; Kidney Diseases; Ureteral Diseases; Ureteral Obstruction	Children's Mercy Hospital Kansas City	2005-08	PHASE2
NCT00309673	UNKNOWN	Tuberculosis	Assistance Publique - Hôpitaux de Paris
NCT00284583	UNKNOWN	Morton's Neuroma	Brown University	2005-05
NCT00258622	COMPLETED	Pain	Danish Pain Research Center	2005-11	PHASE2
NCT00146926	UNKNOWN	Induction of Total Intravenous General Anesthesia	Hospices Civils de Lyon	2005-09	PHASE3
NCT00373893	COMPLETED	Pain; Hyperalgesia	University of California, San Diego	2005-12	PHASE1
NCT00521703	COMPLETED	Dyspepsia; Malabsorption Syndrome; Gastroesophageal Reflux Disease; Abdominal Pain	Hospital Infantil Cândido Fontoura	2007-08	PHASE3
NCT00498992	UNKNOWN	Dermatologic Complications; Unspecified Adult Solid Tumor, Protocol Specific	Ingalls Memorial Hospital	2006-07
NCT00229567	TERMINATED	Colorectal Cancer	University of Saskatchewan	2005-09
NCT00121498	COMPLETED	Pain	Rambam Health Care Campus	2002-11

(data from https://clinicaltrials.gov, updated on 2026-01-23)

Check the Lidocaine hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Lidocaine hydrochloride binds to and inhibits the epidermal growth factor receptor (EGFR), blocking downstream signaling pathways to reduce cell proliferation in tongue cancer cells. This receptor inhibition and attenuation of cellular signal transduction result in antiproliferative and anesthetic effects, supporting its clinical relevance in managing surgical pain, nerve blocks, and oncological conditions.

Appendix RUO and cGMP Quality Standards

Quality Dimension	RUO (Research Use Only)	cGMP (Current Good Manufacturing Practice)
Clinical Applicability	Prohibited in human clinical trials or medical diagnostics.	Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status	Non-regulated grade; exempt from drug manufacturing laws.	Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment	Unclassified analytical or research laboratories.	Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control	Basic purity and activity testing.	Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation	Basic equipment calibration; no process validation required.	Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance	Vendor self-declared without required formal QMS.	Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact	High risk of IND rejection if used as a critical raw material.	Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).