For research use only. Not for use in humans.

lexatumumab (Anti-TNFRSF10B / TRAILR2 / CD262)

Synonyms: HGS-ETR 2, ETR2-ST01

Lexatumumab (Anti-TNFRSF10B / TRAILR2 / CD262) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. MW : 145.5 KD.

lexatumumab (Anti-TNFRSF10B / TRAILR2 / CD262)

Quality Control

Batch: A233001 Purity: 99% Protein concentration: 4.69mg/ml Endotoxin Level: <1EU/mg
99

Mechanism of Action

Description
Lexatumumab (Anti-TNFRSF10B / TRAILR2 / CD262) is a human agonistic TRAIL receptor 2 (TRAIL-R2, DR5, APO-2) IgG4κ type monoclonal antibody. Lexatumumab induces apoptosis in malignant mesothelioma. MW : 145.5 KD.

Product Details

CAS No. 845816-02-6
Molecular Weight 145.5 kDa
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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