E7080 (Lenvatinib) is a potent, multi-targeted VEGFR, FGFR, PDGFR, and RET kinase inhibitor. It affects PI3K/AKT/mTOR and RAF/MEK/ERK signaling pathways, and by blocking these receptor tyrosine kinases, it inhibits tumor cell proliferation, migration, and angiogenesis, while promoting apoptosis.
E7080 (Lenvatinib) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for E7080 (Lenvatinib) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.