Clinical Trials

Lenalidomide has been extensively evaluated across numerous clinical trials spanning Early Phase 1 through Phase 4, focusing primarily on hematologic malignancies—including multiple myeloma, smoldering multiple myeloma, chronic lymphocytic leukemia, diffuse large B-cell lymphoma, and follicular lymphoma—alongside exploratory studies in neurodegenerative and inflammatory disorders. Sponsored by government institutes, academic medical centers, and pharmaceutical companies, these trials encompass various recruitment statuses, including completed, active, recruiting, terminated, and withdrawn. Together, these studies underscore its broad investigation in diverse therapeutic strategies and combination regimens.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07428369 WITHDRAWN
Multiple Myeloma (MM)
Regeneron Pharmaceuticals
2026-06-05 PHASE2; PHASE3
NCT06932562 RECRUITING
Multiple Myeloma
European Myeloma Network B.V.
2025-12-23 PHASE3
NCT04446962 ACTIVE_NOT_RECRUITING
Lymphoma, Large B-Cell, Diffuse; Central Nervous System Neoplasms, Primary
Institut Curie
2020-10-30 PHASE1; PHASE2
NCT05259839 ACTIVE_NOT_RECRUITING
Relapsed/Refractory Multiple Myeloma
AbbVie
2022-10-20 PHASE1
NCT05257083 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Stichting European Myeloma Network
2023-10-10 PHASE3
NCT05145400 RECRUITING
Multiple Myeloma; Cancer
UNC Lineberger Comprehensive Cancer Center
2022-02-18 PHASE2
NCT06974786 RECRUITING
Multiple Myeloma, Newly Diagnosed; Multiple Myeloma (MM)
SCRI Development Innovations, LLC
2025-08-08 PHASE2
NCT05283720 ACTIVE_NOT_RECRUITING
Non-Hodgkin Lymphoma
Genmab
2022-06-14 PHASE2
NCT06182774 RECRUITING
Multiple Myeloma
Canadian Cancer Trials Group
2024-04-10 PHASE3
NCT07285239 RECRUITING
Multiple Myeloma
PrECOG, LLC.
2026-09 PHASE3
NCT05561387 RECRUITING
Plasma Cell Myeloma
SWOG Cancer Research Network
2023-10-12 PHASE3
NCT06679101 RECRUITING
Multiple Myeloma; Newly Diagnosed Multiple Myeloma
GlaxoSmithKline
2024-12-16 PHASE3
NCT07719543 NOT_YET_RECRUITING
Immunoglobulin G4-Related Disease
Chinese PLA General Hospital
2026-08-01 PHASE3
NCT07247097 NOT_YET_RECRUITING
Multiple Myeloma; Newly Diagnosed Multiple Myeloma; Transplant Ineligible; Newly Diagnosed Multiple Myeloma (NDMM)
Massachusetts General Hospital
2026-08-01 PHASE2
NCT06931704 NOT_YET_RECRUITING
Multiple Myeloma
Nantes University Hospital
2025-05-01 PHASE2
NCT06997081 RECRUITING
Multiple Myeloma
University of Miami
2025-09-16 PHASE2
NCT05469893 RECRUITING
High-risk Smoldering Multiple Myeloma; Smoldering Multiple Myeloma; Multiple Myeloma
Irene Ghobrial, MD
2022-08-10 PHASE2
NCT07719855 NOT_YET_RECRUITING
Follicular Lymphoma ( FL)
Ruijin Hospital
2026-07 PHASE3
NCT05867030 WITHDRAWN
Follicular Lymphoma
Innovent Biologics (Suzhou) Co. Ltd.
2023-07-28 PHASE1
NCT04539236 SUSPENDED
Myelodysplastic Syndromes
Mikkael Sekeres, MD
2021-11-09 PHASE1; PHASE2
NCT05848765 RECRUITING
Relapsed Follicular Lymphoma; Refractory Follicular Lymphoma
University of Birmingham
2023-09-04 PHASE2
NCT04669171 RECRUITING
Follicular Lymphoma; Marginal Zone Lymphoma
Enterome
2021-07-05 PHASE1; PHASE2
NCT05827016 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Bristol-Myers Squibb
2023-06-22 PHASE3
NCT06965244 NOT_YET_RECRUITING
Cutaneous Lupus Erythematosus (CLE)
Assistance Publique - Hôpitaux de Paris
2025-10-01 PHASE3
NCT07764978 RECRUITING
Newly Diagnosed Multiple Myeloma
AstraZeneca
2026-06-26 PHASE3
NCT06665217 NOT_YET_RECRUITING
Diffuse Large B-Cell Lymphoma
Navy General Hospital, Beijing
2025-09-24 PHASE2
NCT07709884 NOT_YET_RECRUITING
Newly Diagnosed Multiple Myeloma; T(11;14); Sotoclax; Carfilzomib
The First Affiliated Hospital of Soochow University
2026-07-01 PHASE4
NCT07514169 RECRUITING
Large B-Cell Lymphoma (LBCL)
Ruijin Hospital
2026-03-31 PHASE2
NCT07735637 NOT_YET_RECRUITING
Newly Diagnosed Multiple Myeloma (NDMM)
AstraZeneca
2026-08-25 PHASE3
NCT05695508 RECRUITING
Multiple Myeloma
University of Heidelberg Medical Center
2022-12-01 PHASE2
NCT06522555 RECRUITING
Diffuse Large B-Cell Lymphoma
Ruijin Hospital
2024-07-29 PHASE3
NCT05583617 RECRUITING
Multiple Myeloma
Hoffmann-La Roche
2023-11-14 PHASE1; PHASE2
NCT05888493 ACTIVE_NOT_RECRUITING
Follicular Lymphoma (FL)
Novartis Pharmaceuticals
2023-10-02 PHASE3
NCT07068165 RECRUITING
IgG4 Related Disease
Peking Union Medical College Hospital
2025-07-07 PHASE2; PHASE3
NCT07355283 NOT_YET_RECRUITING
Relapsed/Refractory Follicular Lymphoma
ImmuneOnco Biopharmaceuticals (Shanghai) Inc.
2026-02 PHASE3
NCT05100862 ACTIVE_NOT_RECRUITING
Relapsed/Refractory Follicular Lymphoma; Marginal Zone Lymphoma
BeOne Medicines
2022-03-10 PHASE3
NCT07639138 RECRUITING
Hepatocellular Carcinoma (HCC)
Shunda Du
2026-06-10 PHASE2
NCT07208981 RECRUITING
Marginal Zone Lymphoma(MZL)
The First Affiliated Hospital with Nanjing Medical University
2025-08-14 PHASE2
NCT05846880 RECRUITING
Multiple Myeloma
Amany Keruakous, MD, MS.
2024-12-01 EARLY_PHASE1
NCT07562022 RECRUITING
Follicular Lymphoma (FL)
Sinocelltech Ltd.
2026-06-09 PHASE3
NCT05243797 RECRUITING
Multiple Myeloma
European Myeloma Network B.V.
2022-09-08 PHASE3
NCT07045909 RECRUITING
De Novo Multiple Myeloma; Anitocabtagene Autoleucel
PETHEMA Foundation
2025-06-30 PHASE2
NCT05137054 RECRUITING
Multiple Myeloma
Regeneron Pharmaceuticals
2022-08-17 PHASE1
NCT06508658 ACTIVE_NOT_RECRUITING
Diffuse Large B-Cell Lymphoma
Genmab
2024-08-13 PHASE3
NCT06744894 NOT_YET_RECRUITING
Multiple Myeloma
Navy General Hospital, Beijing
2025-01-01 PHASE2
NCT06651853 RECRUITING
Diffuse Large B-cell Lymphoma; Relapsed and Refractory
The First Affiliated Hospital of Xiamen University
2024-10-21 PHASE2
NCT04775550 ACTIVE_NOT_RECRUITING
High-risk Smoldering Multiple Myeloma; Multiple Myeloma
Omar Nadeem, MD
2021-03-08 PHASE2
NCT06742138 NOT_YET_RECRUITING
Multiple Myeloma
Qilu Pharmaceutical Co., Ltd.
2025-01 PHASE3
NCT06409702 RECRUITING
Newly Diagnosed; High Risk; MRD; Multiple Myeloma
The First Affiliated Hospital of Soochow University
2024-06-12 PHASE4
NCT07018050 RECRUITING
Relapsed or Refractory Multiple Myeloma
Qilu Pharmaceutical Co., Ltd.
2025-09-12 PHASE2
NCT02659293 ACTIVE_NOT_RECRUITING
Multiple Myeloma
University of Chicago
2016-04-26 PHASE3
NCT07789522 NOT_YET_RECRUITING
Multiple Myeloma (MM)
Institute of Hematology & Blood Diseases Hospital, China
2026-10-01 PHASE2
NCT05683171 ACTIVE_NOT_RECRUITING
Lymphoma
M.D. Anderson Cancer Center
2023-05-19 PHASE1; PHASE2
NCT04542824 ACTIVE_NOT_RECRUITING
Diffuse Large B Cell Lymphoma; High-grade B-cell Lymphoma; Primary Mediastinal Large B Cell Lymphoma; Follicular Lymphoma; Marginal Zone Lymphoma; Small Lymphocytic Lymphoma
Genmab
2020-08-20 PHASE1; PHASE2
NCT04792502 RECRUITING
Follicular Lymphoma; Marginal Zone Lymphoma; B-cell Lymphoma
Brown University
2022-07-14 PHASE2
NCT06084936 RECRUITING
Lymphoma
Hoffmann-La Roche
2023-10-22 PHASE3
NCT05317416 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Pfizer
2022-03-25 PHASE3
NCT05665140 RECRUITING
Newly Diagnosed Multiple Myeloma
University Hopsital Schleswig Holstein Campus Lübeck
2023-02-03 PHASE2; PHASE3
NCT07261163 RECRUITING
Mantle Cell Lymphoma
Institute of Hematology & Blood Diseases Hospital, China
2025-12-20 PHASE2
NCT06895512 NOT_YET_RECRUITING
Newly Diagnosed Multiple Myeloma
Shanghai Henlius Biotech
2025-04 PHASE3
NCT05279300 SUSPENDED
Advanced Solid Tumor; Advanced Lymphoma
CStone Pharmaceuticals
2022-03-28 PHASE1
NCT04301076 RECRUITING
Acute Adult T-Cell Leukemia/Lymphoma; Adult T-Cell Leukemia/Lymphoma; Chronic Adult T-Cell Leukemia/Lymphoma; HTLV-1 Infection
National Cancer Institute (NCI)
2021-08-31 PHASE1
NCT01297764 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Hackensack Meridian Health
2011-04 PHASE1; PHASE2
NCT06348147 WITHDRAWN
Newly Diagnosed Multiple Myeloma; Multiple Myeloma; Autologous Stem Cell Transplantation
UNC Lineberger Comprehensive Cancer Center
2026-07 PHASE2
NCT02420860 ACTIVE_NOT_RECRUITING
Hematopoietic Cell Transplantation Recipient; Plasma Cell Myeloma
M.D. Anderson Cancer Center
2015-04-14 PHASE2
NCT07187167 RECRUITING
Rosai-Dorfman Disease
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
2025-04-12 PHASE2
NCT07081022 ACTIVE_NOT_RECRUITING
B-cell Non-Hodgkin's Lymphoma
Shanghai Junshi Bioscience Co., Ltd.
2025-08-17 PHASE2
NCT03319667 ACTIVE_NOT_RECRUITING
Plasma Cell Myeloma
Sanofi
2017-12-07 PHASE3
NCT05558319 RECRUITING
Newly Diagnosed Multiple Myeloma
PETHEMA Foundation
2022-11-10 PHASE3
NCT04133636 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Janssen Research & Development, LLC
2019-11-07 PHASE2
NCT04224493 ACTIVE_NOT_RECRUITING
Relapsed/Refractory Follicular Lymphoma; Follicular Lymphoma; Refractory Follicular Lymphoma
Epizyme, Inc.
2020-06-11 PHASE3
NCT05861050 RECRUITING
Blastoid Variant Mantle Cell Lymphoma; Mantle Cell Lymphoma; Pleomorphic Variant Mantle Cell Lymphoma
City of Hope Medical Center
2023-08-10 PHASE1; PHASE2
NCT03070327 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Memorial Sloan Kettering Cancer Center
2017-02-27 PHASE1
NCT04978584 ACTIVE_NOT_RECRUITING
Diffuse Large B-Cell Lymphoma
M.D. Anderson Cancer Center
2022-03-03 PHASE2
NCT03829371 ACTIVE_NOT_RECRUITING
Multiple Myeloma
University of Turin, Italy
2019-01-03 PHASE4
NCT07764861 NOT_YET_RECRUITING
Multiple Myeloma
Innovent Biologics (Suzhou) Co. Ltd.
2026-08-15 PHASE2
NCT06764017 RECRUITING
Diffuse Large B-Cell Lymphoma
First Affiliated Hospital of Ningbo University
2025-02-01 PHASE2
NCT05890352 RECRUITING
Grade 3b Follicular Lymphoma; High Grade B-Cell Lymphoma; High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements; Recurrent Diffuse Large B-Cell Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Transformed Non-Hodgkin Lymphoma
SWOG Cancer Research Network
2023-09-26 PHASE2
NCT05950165 ACTIVE_NOT_RECRUITING
Non-Hodgkin Lymphoma
Cho Pharma Inc.
2020-01-15 PHASE1; PHASE2
NCT04009109 ACTIVE_NOT_RECRUITING
Myeloma, Multiple
Alliance Foundation Trials, LLC.
2020-10-21 PHASE2
NCT01562405 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Massachusetts General Hospital
2012-05 PHASE1
NCT06517017 RECRUITING
Multiple Myeloma; Plasma Cell Leukemia
University of Utah
2025-10-09 PHASE2
NCT06505369 RECRUITING
Multiple Myeloma
North Estonia Medical Centre
2024-06-19 PHASE2
NCT06414148 RECRUITING
Relapsed/Refractory Large B-cell Lymphoma
Peter MacCallum Cancer Centre, Australia
2024-05-14 PHASE2
NCT02886065 ACTIVE_NOT_RECRUITING
Smoldering Multiple Myeloma
Massachusetts General Hospital
2017-03-07 PHASE1
NCT05690984 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Medical College of Wisconsin
2023-06-26 PHASE2
NCT06762431 RECRUITING
Chronic Lymphocytic Leukaemia (CLL); Small Lymphocytic Lymphoma (SLL)
Vitebsk Regional Clinical Cancer Centre
2024-05-14 PHASE1; PHASE2
NCT07090954 NOT_YET_RECRUITING
Multiple Myeloma
Genrix (Shanghai) Biopharmaceutical Co., Ltd.
2025-08-31 PHASE1; PHASE2
NCT04635189 ACTIVE_NOT_RECRUITING
Multiple Myeloma
University of Rochester
2021-07-27 PHASE2
NCT03836014 ACTIVE_NOT_RECRUITING
Multiple Myeloma in Relapse
Assistance Publique - Hôpitaux de Paris
2019-07-25 PHASE3
NCT06737250 RECRUITING
Primary CNS Lymphoma (PCNSL)
NOBO Medicine
2024-11-25 PHASE2
NCT05660967 TERMINATED
Diffuse Large B-Cell Lymphoma
Genmab
2023-03-06 PHASE2
NCT05351346 UNKNOWN
Diffuse Large B Cell Lymphoma
Ruijin Hospital
2022-06-01 PHASE3
NCT06454968 RECRUITING
Marginal Zone Lymphoma
Peking Union Medical College Hospital
2024-06-20 PHASE2
NCT03697356 UNKNOWN
Waldenström's Macroglobulinemia
Kosin University Gospel Hospital
2019-03-06 PHASE2
NCT05846750 RECRUITING
Marginal Zone Lymphoma
Institute of Hematology & Blood Diseases Hospital, China
2022-11-01 PHASE2
NCT02544308 ACTIVE_NOT_RECRUITING
Plasmacytoma
University College, London
2017-03-10 PHASE3
NCT05572229 RECRUITING
Multiple Myeloma
University Hospital, Lille
2023-12-21 PHASE2
NCT05429268 ACTIVE_NOT_RECRUITING
Large B-Cell Lymphoma; Diffuse Large B-Cell Lymphoma
Incyte Corporation
2022-12-23 PHASE3
NCT05849610 ACTIVE_NOT_RECRUITING
High-Risk de Novo Multiple Myeloma
PETHEMA Foundation
2023-09-21 PHASE2
NCT04786028 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Canadian Myeloma Research Group
2021-12-08 PHASE2
NCT06177028 NOT_YET_RECRUITING
Cognitive Impairment, Mild; Cognitive Dysfunction; Amyloid Plaque; Neurodegenerative Disease, Hereditary; Inflammation, Brain
St. Joseph's Hospital and Medical Center, Phoenix
2025-06-01 PHASE2
NCT04096066 ACTIVE_NOT_RECRUITING
Multiple Myeloma; New Diagnosis Tumor
Fondazione EMN Italy Onlus
2019-07-01 PHASE3
NCT03269669 ACTIVE_NOT_RECRUITING
Grade 1 Follicular Lymphoma; Grade 2 Follicular Lymphoma; Grade 3a Follicular Lymphoma; Recurrent Follicular Lymphoma; Refractory Follicular Lymphoma
National Cancer Institute (NCI)
2018-01-23 PHASE2
NCT04941937 UNKNOWN
Multiple Myeloma
Juan Du
2022-01-27 PHASE2
NCT03641456 UNKNOWN
Myeloma; Newly Diagnosed; High Risk
Sun Yat-sen University
2020-09-25 PHASE2
NCT05179733 UNKNOWN
Diffuse Large B-Cell Lymphoma
Ruijin Hospital
2022-03-02 PHASE3
NCT05572515 ACTIVE_NOT_RECRUITING
Relapsed or Refractory Multiple Myeloma
Janssen Research & Development, LLC
2023-03-29 PHASE3
NCT04722146 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Janssen Research & Development, LLC
2021-03-12 PHASE1
NCT05992597 RECRUITING
Rituximab, Lenalidomide, Zebutinib ,Mantle Cell Lymphoma
Zhejiang Cancer Hospital
2022-08-01 PHASE2
NCT04737889 RECRUITING
Primary Central Nervous System Lymphoma
Henan Cancer Hospital
2021-01-13 PHASE2
NCT04091126 ACTIVE_NOT_RECRUITING
Multiple Myeloma
GlaxoSmithKline
2019-12-18 PHASE1
NCT04032626 COMPLETED
Cognitive Impairment, Mild; Cognitive Dysfunction; Amyloid Plaque; Neurodegeneration; Inflammation, Brain
St. Joseph's Hospital and Medical Center, Phoenix
2020-07-22 PHASE2
NCT05428670 UNKNOWN
Diffuse Large B Cell Lymphoma
First Affiliated Hospital of Wenzhou Medical University
2022-06-15 PHASE2
NCT02005289 COMPLETED
Contiguous Stage II Small Lymphocytic Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Prolymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Stage I Chronic Lymphocytic Leukemia; Stage I Small Lymphocytic Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage III Chronic Lymphocytic Leukemia; Stage III Small Lymphocytic Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Small Lymphocytic Lymphoma
Ohio State University Comprehensive Cancer Center
2014-01-17 PHASE2
NCT05771883 UNKNOWN
B-cell Non-Hodgkin's Lymphoma
ImmuneOnco Biopharmaceuticals (Shanghai) Inc.
2023-05 PHASE1; PHASE2
NCT07150091 ACTIVE_NOT_RECRUITING
Multiple Myeloma
GlaxoSmithKline
2022-07-19 PHASE1; PHASE2
NCT05201248 ACTIVE_NOT_RECRUITING
B-Cell Non-Hodgkin Lymphoma
Genmab
2022-03-10 PHASE1; PHASE2
NCT05050097 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Janssen Research & Development, LLC
2021-09-22 PHASE1
NCT02446457 ACTIVE_NOT_RECRUITING
Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3a Follicular Lymphoma
M.D. Anderson Cancer Center
2015-07-31 PHASE2
NCT02916771 COMPLETED
Smoldering Multiple Myeloma
Dana-Farber Cancer Institute
2016-10 PHASE2
NCT04288765 WITHDRAWN
Multiple Myeloma
Grupo Cooperativo de Hemopatías Malignas
2020-03-01 PHASE3
NCT05265975 TERMINATED
Diffuse Large B-cell Lymphoma; Indolent Non-Hodgkin Lymphoma
Antengene Corporation
2022-04-07 PHASE1; PHASE2
NCT04432714 RECRUITING
DLBCL; Untreated; MYC Gene Rearrangement
The First Affiliated Hospital with Nanjing Medical University
2020-06-09 PHASE1; PHASE2
NCT05147493 UNKNOWN
Multiple Myeloma; Renal Impairment; Neoplasms, Plasma Cell; Neoplasms by Histologic Type; Neoplasms; Paraproteinemias; Blood Protein Disorders; Hematologic Diseases
Hellenic Society of Hematology
2022-04 PHASE2
NCT03720041 UNKNOWN
Multiple Myeloma
University of Leeds
2020-08-04 PHASE3
NCT06189833 UNKNOWN
Multiple Myeloma
Stichting European Myeloma Network
2023-11-23 PHASE2
NCT05060627 ACTIVE_NOT_RECRUITING
Relapsed Multiple Myeloma
PETHEMA Foundation
2021-12-20 PHASE1; PHASE2
NCT02911142 ACTIVE_NOT_RECRUITING
Primary Effusion Lymphoma; B-Cell Neoplasm
National Cancer Institute (NCI)
2017-07-03 PHASE1; PHASE2
NCT02575144 UNKNOWN
Multiple Myeloma
PETHEMA Foundation
2015-09 PHASE3
NCT03702725 COMPLETED
Refractory Multiple Myeloma; Multiple Myeloma in Relapse; Multiple Myeloma
Alliance Foundation Trials, LLC.
2019-08-29 PHASE1
NCT05032820 COMPLETED
Multiple Myeloma
Medical College of Wisconsin
2022-01-05 PHASE2
NCT05788289 TERMINATED
Mantle Cell Lymphoma; MCL
Memorial Sloan Kettering Cancer Center
2023-03-14 PHASE2
NCT05222555 ACTIVE_NOT_RECRUITING
Diffuse Large B Cell Lymphoma
Incyte Corporation
2022-07-19 PHASE1; PHASE2
NCT05797948 UNKNOWN
Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
The First Affiliated Hospital of Soochow University
2022-07-01
NCT01729091 COMPLETED
Plasma Cell Leukemia; Plasma Cell Myeloma
M.D. Anderson Cancer Center
2013-06-10 PHASE2
NCT04113226 COMPLETED
Chemotherapy; Diffuse Large B-Cell Lymphoma (DLBCL), Nos; Elderly
Centre Hospitalier Universitaire, Amiens
2021-11-09 PHASE2
NCT05211336 ACTIVE_NOT_RECRUITING
Primary Diffuse Large B-cell Lymphoma of the Central Nervous System (CNS); Aggressive B-cell Lymphoma With Secondary Involvement of the CNS
National Cancer Institute (NCI)
2022-04-19 PHASE1
NCT01919086 COMPLETED
Multiple Myeloma (MM)
Memorial Sloan Kettering Cancer Center
2013-08-06 PHASE2
NCT01996865 COMPLETED
Lymphoma, Non-Hodgkin
Celgene
2014-04-01 PHASE3
NCT04140162 ACTIVE_NOT_RECRUITING
Multiple Myeloma
University of Michigan Rogel Cancer Center
2020-10-05 PHASE2
NCT05497102 UNKNOWN
Multiple Myeloma
Samsung Medical Center
2021-11-08 PHASE2
NCT01476787 COMPLETED
Follicular Lymphoma
Celgene
2011-12-29 PHASE3
NCT03863184 ACTIVE_NOT_RECRUITING
Mantle Cell Lymphoma
Weill Medical College of Cornell University
2019-10-11 PHASE2
NCT05105412 TERMINATED
Peripheral T-cell Lymphomas (PTCL)
National Health Research Institutes, Taiwan
2022-06-15 PHASE1; PHASE2
NCT04436107 COMPLETED
Relapsed/Refractory Diffuse Large B-Cell Lymphoma
BeiGene
2020-09-11 PHASE1
NCT03413800 COMPLETED
Relapsed Hematologic Malignancy; Multiple Myeloma
Ciusss de L'Est de l'Île de Montréal
2018-02-12 PHASE2
NCT04892264 TERMINATED
Plasma Cell Myeloma; Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma
Mayo Clinic
2021-06-03 PHASE1
NCT05288062 TERMINATED
Plasma Cell Myeloma; Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma; Smoldering Plasma Cell Myeloma
Mayo Clinic
2022-06-15 PHASE2
NCT04680052 ACTIVE_NOT_RECRUITING
Follicular Lymphoma; Marginal Zone Lymphoma
Incyte Corporation
2021-04-15 PHASE3
NCT05200312 UNKNOWN
Non Hodgkin Lymphoma; Diffuse Large B Cell Lymphoma
The First Affiliated Hospital with Nanjing Medical University
2022-02-01 PHASE2
NCT03269136 COMPLETED
Multiple Myeloma
Pfizer
2017-11-29 PHASE1
NCT04352205 TERMINATED
Plasma Cell Myeloma; Renal Failure
Emory University
2020-05-07 PHASE2
NCT05186558 UNKNOWN
Lymphoma, Large B-Cell, Diffuse; Neoplasms by Histologic Type
The First Affiliated Hospital with Nanjing Medical University
2022-05-15 PHASE2
NCT04110301 RECRUITING
Follicular Lymphoma and Marginal Zone Lymphoma
Beijing Mabworks Biotech Co., Ltd.
2019-11-28 PHASE1; PHASE2
NCT05784987 UNKNOWN
Diffuse Large B-cell Lymphoma
The First Affiliated Hospital with Nanjing Medical University
2023-04-15
NCT06177028 Not yet recruiting
Cognitive Impairment Mild|Cognitive Dysfunction|Amyloid Plaque|Neurodegenerative Disease Hereditary|Inflammation Brain
St. Joseph''s Hospital and Medical Center Phoenix|Texas Tech University
2024-01-02 Phase 2
NCT04129710 UNKNOWN
Recurrent/RefractoryPrimary Central Nervous System Lymphoma (PCNSL)
Second Affiliated Hospital, Zhejiang University, School of Medicine
2020-01-01 PHASE2
NCT04214626 COMPLETED
Diffuse Large B Cell Lymphoma
Henan Cancer Hospital
2020-01-05 PHASE2
NCT04635683 WITHDRAWN
Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue; Recurrent Follicular Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3a Follicular Lymphoma; Recurrent Lymphoplasmacytic Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Nodal Marginal Zone Lymphoma; Recurrent Splenic Marginal Zone Lymphoma; Recurrent Waldenstrom Macroglobulinemia; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue; Refractory Follicular Lymphoma; Refractory Grade 1 Follicular Lymphoma; Refractory Grade 2 Follicular Lymphoma; Refractory Grade 3a Follicular Lymphoma; Refractory Lymphoplasmacytic Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Marginal Zone Lymphoma; Refractory Nodal Marginal Zone Lymphoma; Refractory Splenic Marginal Zone Lymphoma; Refractory Waldenstrom Macroglobulinemia
Yazeed Sawalha
2022-09-30 PHASE1
NCT04049864 UNKNOWN
Relapsed Neuroblastoma
Belarusian Research Center for Pediatric Oncology, Hematology and Immunology
2019-01-09 EARLY_PHASE1
NCT04922567 RECRUITING
Peripheral T-Cell Lymphoma; Lenalidomide; CHOP
Second Affiliated Hospital, Zhejiang University, School of Medicine
2021-04-01 PHASE2
NCT04481815 UNKNOWN
PCNSL
Second Affiliated Hospital, Zhejiang University, School of Medicine
2020-10-01 PHASE2
NCT04842487 UNKNOWN
DLBCL
Sun Yat-sen University
2021-04-10 PHASE2
NCT04578600 COMPLETED
Indolent B-Cell Non-Hodgkin Lymphoma; Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Mucosa-Associated Lymphoid Tissue Lymphoma; Recurrent Follicular Lymphoma; Recurrent Hairy Cell Leukemia; Recurrent Lymphoplasmacytic Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Mucosa-Associated Lymphoid Tissue Lymphoma; Refractory Follicular Lymphoma; Refractory Hairy Cell Leukemia; Refractory Lymphoplasmacytic Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Small Lymphocytic Lymphoma
Joseph Tuscano
2020-10-23 PHASE1
NCT05564052 COMPLETED
Lymphoma, Mantle-Cell
Janssen Research & Development, LLC
2022-12-06 PHASE2
NCT06149286 Recruiting
Relapsed/Refractory Follicular Lymphoma|Marginal Zone Lymphoma (MZL)
Regeneron Pharmaceuticals
2023-12-28 Phase 3
NCT06299553 Recruiting
DLBCL - Diffuse Large B Cell Lymphoma
Incyte Biosciences Italy S.r.l
2023-12-04 --
NCT04151667 COMPLETED
Multiple Myeloma
H. Lee Moffitt Cancer Center and Research Institute
2019-11-22 PHASE2
NCT01755975 COMPLETED
Multiple Myeloma; Non-Hodgkin's Lymphoma
Memorial Sloan Kettering Cancer Center
2012-12 PHASE1; PHASE2
NCT03289299 ACTIVE_NOT_RECRUITING
Smoldering Multiple Myeloma
International Myeloma Foundation
2018-05-25 PHASE2
NCT02180711 ACTIVE_NOT_RECRUITING
Non Hodgkin Lymphoma
Acerta Pharma BV
2014-12-29 PHASE1; PHASE2
NCT02532257 COMPLETED
Ann Arbor Stage II Follicular Lymphoma; Ann Arbor Stage II Marginal Zone Lymphoma; Ann Arbor Stage III Follicular Lymphoma; Ann Arbor Stage III Marginal Zone Lymphoma; Ann Arbor Stage IV Follicular Lymphoma; Ann Arbor Stage IV Marginal Zone Lymphoma; CD20 Positive; Grade 1 Follicular Lymphoma; Grade 2 Follicular Lymphoma; Grade 3a Follicular Lymphoma
M.D. Anderson Cancer Center
2016-04-11 PHASE2
NCT03710603 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Stichting European Myeloma Network
2018-12-14 PHASE3
NCT05488327 UNKNOWN
Dermatomyositis
Jiangxi Provincial People's Hopital
2022-08-01
NCT00848328 TERMINATED
Lymphoma
University of California, Davis
2008-08-25 PHASE2
NCT04113018 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Wake Forest University Health Sciences
2020-01-10 PHASE2
NCT01749969 COMPLETED
Plasma Cell Myeloma
Sanofi
2013-02-06 PHASE1
NCT04796857 UNKNOWN
Non-GCB/ABC Diffuse Large B-Cell Lymphoma; High-grade B-cell Lymphoma; Follicular Lymphoma Grade IIIb; Transformed Lymphoma; EBV-Positive DLBCL, Nos; ALK-Positive Anaplastic Large Cell Lymphoma
Huiqiang Huang
2021-03-31 PHASE1; PHASE2
NCT04842318 UNKNOWN
Follicular Lymphoma
Ruijin Hospital
2021-03-01 PHASE4
NCT03544281 COMPLETED
Multiple Myeloma
GlaxoSmithKline
2018-09-20 PHASE1; PHASE2
NCT04818372 UNKNOWN
Multiple Myeloma; Lymphoma
Keymed Biosciences Co.Ltd
2021-04-26 PHASE1
NCT04432402 UNKNOWN
Diffuse Large B Cell Lymphoma
The First Affiliated Hospital with Nanjing Medical University
2020-06-14
NCT04604028 UNKNOWN
Antibiotics-unresponsive MALT Lymphoma; Relapsed MALT Type Extranodal Marginal Zone B-Cell Lymphoma; Refractory Extranodal Marginal Zone B-Cell Lymphoma (MALT)
National Taiwan University Hospital
2020-11-10 PHASE2
NCT02636322 COMPLETED
Diffuse Large B-Cell Lymphoma Unclassifiable
M.D. Anderson Cancer Center
2016-03-29 PHASE2
NCT05014100 UNKNOWN
B-cell Lymphoma
Puyang Oilfield General Hospital
2021-09-01 PHASE2
NCT02334865 ACTIVE_NOT_RECRUITING
Partial Response of Multiple Myeloma or Plasma Cell Leukemia; Plasma Cell Myeloma
Roswell Park Cancer Institute
2017-04-13 PHASE1
NCT04120350 UNKNOWN
Primary Central Nervous System Lymphoma
Peking Union Medical College Hospital
2019-08-16 PHASE1; PHASE2
NCT04430894 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Massachusetts General Hospital
2020-07-10 PHASE2
NCT02215980 COMPLETED
Multiple Myeloma
Fondazione EMN Italy Onlus
2014-07 PHASE3
NCT01754857 COMPLETED
Lymphoid Leukemia; Small Lymphocytic Lymphoma; Lymphoma, Non-Hodgkin
University of Wisconsin, Madison
2013-11-12 PHASE2
NCT00551928 COMPLETED
Multiple Myeloma; Newly Diagnosed Patients
Fondazione EMN Italy Onlus
2007-06 PHASE3
NCT03379051 TERMINATED
Chronic Lymphocytic Leukemia; Non-Hodgkin Lymphoma
TG Therapeutics, Inc.
2018-03-27 PHASE1; PHASE2
NCT03477539 COMPLETED
Plasma Cell Myeloma
Mayo Clinic
2018-04-09 PHASE2
NCT03113695 COMPLETED
Richter's Syndrome; CLL
University of California, San Diego
2017-12-20 PHASE1
NCT02906332 TERMINATED
Multiple Myeloma
Hackensack Meridian Health
2016-12-12 PHASE2
NCT03003520 COMPLETED
Lymphoma, Large B-Cell, Diffuse
Celgene
2017-02-28 PHASE2
NCT02461888 COMPLETED
Multiple Myeloma
University of Leeds
2015-12 PHASE2
NCT04329130 UNKNOWN
Relapsed or Refractory Peripheral T-cell Lymphoma
Sun Yat-sen University
2020-03-27 PHASE2
NCT04277845 UNKNOWN
Multiple Myeloma
Samsung Medical Center
2020-08-06 PHASE2
NCT04231370 UNKNOWN
NK/T Cell Lymphoma Nos
Beijing Tongren Hospital
2020-04-01 PHASE2
NCT01208662 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Paul Richardson, MD
2010-09 PHASE3
NCT02513186 COMPLETED
Plasma Cell Myeloma
Sanofi
2015-09-30 PHASE1
NCT01554852 UNKNOWN
Multiple Myeloma
University of Leeds
2010-05 PHASE3
NCT02126553 COMPLETED
Alkylating Agent-Related Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia
M.D. Anderson Cancer Center
2014-11-13 PHASE2
NCT03314636 ACTIVE_NOT_RECRUITING
Myeloma
Oslo University Hospital
2018-03-16 PHASE2
NCT01054196 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Weill Medical College of Cornell University
2010-08 PHASE1; PHASE2
NCT02628405 UNKNOWN
Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Recurrent Transformed Non-Hodgkin Lymphoma; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma; Refractory Transformed Non-Hodgkin Lymphoma
Academic and Community Cancer Research United
2016-05-20 PHASE1; PHASE2
NCT03015922 UNKNOWN
Multiple Myeloma
University of Leeds
2017-06-05 PHASE1
NCT01091831 COMPLETED
Multiple Myeloma
Fondazione EMN Italy Onlus
2009-07 PHASE3
NCT04065789 COMPLETED
Myeloma Multiple; Myeloma, Plasma-Cell; Myeloma-Multiple; Plasma Cell Myeloma
Tel-Aviv Sourasky Medical Center
2018-05-02 PHASE2
NCT01038388 COMPLETED
Multiple Myeloma
Emory University
2010-01-15 PHASE1
NCT03232307 WITHDRAWN
CCND1 Positive; CD20-Positive Neoplastic Cells Present; Mantle Cell Lymphoma
M.D. Anderson Cancer Center
2019-07-01 PHASE2
NCT03416374 COMPLETED
Relapsed and/or Refractory Multiple Myeloma
Takeda
2018-02-18 PHASE4
NCT00670358 COMPLETED
Lymphoma
Mayo Clinic
2008-08-25 PHASE1; PHASE2
NCT01463670 COMPLETED
Multiple Myeloma
Memorial Sloan Kettering Cancer Center
2011-10-28 PHASE2
NCT01583283 COMPLETED
Multiple Myeloma
Celgene
2012-07-12 PHASE1
NCT03645395 TERMINATED
Non-hodgkin Lymphoma
Molecular Templates, Inc.
2019-04-08 PHASE2
NCT03949062 UNKNOWN
Diffuse Large B Cell Lymphoma
Ruijin Hospital
2019-03-13 PHASE2
NCT03151811 TERMINATED
Multiple Myeloma
Oncopeptides AB
2017-06-12 PHASE3
NCT03891355 UNKNOWN
Mantle Cell Lymphoma
Fondazione Italiana Linfomi - ETS
2019-09-30 PHASE2
NCT04040491 UNKNOWN
Peripheral T-cell Lymphoma
Mingzhi Zhang
2019-09-01 PHASE4
NCT01208766 COMPLETED
Multiple Myeloma
Stichting Hemato-Oncologie voor Volwassenen Nederland
2011-01 PHASE3
NCT01865110 COMPLETED
Mantle Cell Lymphoma
The Lymphoma Academic Research Organisation
2013-11 PHASE3
NCT01886859 COMPLETED
Recurrent B-Cell Prolymphocytic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory B-Cell Prolymphocytic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Small Lymphocytic Lymphoma
National Cancer Institute (NCI)
2013-04-26 PHASE1
NCT00774345 COMPLETED
B-cell Chronic Lymphocytic Leukemia
Celgene
2009-01-27 PHASE3
NCT03283046 WITHDRAWN
Malignant Neoplasms Stated as Primary Lymphoid Haematopoietic; Multiple Myeloma
M.D. Anderson Cancer Center
2017-10 PHASE1
NCT02802163 WITHDRAWN
Multiple Myeloma
H. Lee Moffitt Cancer Center and Research Institute
2017-06 PHASE1; PHASE2
NCT03412565 COMPLETED
Multiple Myeloma
Janssen Research & Development, LLC
2018-04-26 PHASE2
NCT00792077 COMPLETED
Leukemia; CLL
M.D. Anderson Cancer Center
2008-11 PHASE2
NCT01054144 COMPLETED
Multiple Myeloma
H. Lee Moffitt Cancer Center and Research Institute
2010-01-14 PHASE2
NCT02954406 TERMINATED
Lymphoma, Non-Hodgkin
Millennium Pharmaceuticals, Inc.
2017-03-05 PHASE1
NCT01772420 COMPLETED
Adult Myelodysplastic Syndrome; Anemia; Chronic Myelomonocytic Leukemia
Albert Einstein College of Medicine
2012-10 PHASE2
NCT03150316 UNKNOWN
Myeloma, Multiple
Chong Kun Dang Pharmaceutical
2017-05-10 PHASE1
NCT01953692 COMPLETED
Myelodysplastic Syndrome; Multiple Myeloma; Hodgkin Lymphoma; Non-Hodgkin Lymphoma; Diffuse Large B-Cell Lymphoma; Follicular Lymphoma; Primary Mediastinal B-Cell Lymphoma
Merck Sharp & Dohme LLC
2013-11-22 PHASE1
NCT02472691 COMPLETED
Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Leukemia, Myelomonocytic, Chronic
Heinrich-Heine University, Duesseldorf
2015-05 PHASE2
NCT02626481 COMPLETED
Multiple Myeloma
University Hospital, Lille
2015-12-28 PHASE2
NCT01788189 COMPLETED
B-cell Lymphoma
University Hospital, Essen
2013-01 PHASE1; PHASE2
NCT01668719 COMPLETED
DS Stage I Plasma Cell Myeloma; DS Stage II Plasma Cell Myeloma; DS Stage III Plasma Cell Myeloma
SWOG Cancer Research Network
2012-11 PHASE1; PHASE2
NCT02253316 ACTIVE_NOT_RECRUITING
Multiple Myeloma
Washington University School of Medicine
2015-01-20 PHASE2
NCT04063189 UNKNOWN
Multiple Myeloma in Relapse
The First Hospital of Jilin University
2017-03-21 PHASE2
NCT01208051 COMPLETED
Refractory Differentiated Thyroid Gland Carcinoma; Refractory Thyroid Gland Follicular Carcinoma; Refractory Thyroid Gland Hurthle Cell Carcinoma; Refractory Thyroid Gland Papillary Carcinoma; Unresectable Thyroid Gland Carcinoma
National Cancer Institute (NCI)
2010-09-09 PHASE1; PHASE2
NCT01090089 COMPLETED
Multiple Myeloma
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH
2010-03-01 PHASE3
NCT03795571 UNKNOWN
Diffuse Large B-cell Lymphoma Recurrent; Diffuse Large B Cell Lymphoma Refractory
The First Affiliated Hospital with Nanjing Medical University
2019-01-01 PHASE1
NCT03440411 TERMINATED
Multiple Myeloma
Fondazione EMN Italy Onlus
2016-02-18 PHASE3
NCT01850524 COMPLETED
Multiple Myeloma
Millennium Pharmaceuticals, Inc.
2013-04-29 PHASE3
NCT01216683 COMPLETED
Lymphoma
ECOG-ACRIN Cancer Research Group
2011-02-09 PHASE2
NCT02219178 COMPLETED
Multiple Myeloma
Cancer Trials Ireland
2014-11 PHASE2
NCT01881789 TERMINATED
Multiple Myeloma
Amgen
2013-10-28 PHASE1; PHASE2
NCT02966522 UNKNOWN
Cardiac Amyloidosis
Seoul National University Hospital
2016-10 PHASE2
NCT02917941 COMPLETED
Relapsed and/or Refractory Multiple Myeloma
Takeda
2016-11-01 PHASE2
NCT03359460 COMPLETED
Myelodysplastic Syndrome; Previously Treated Myelodysplastic Syndrome; Refractory High Risk Myelodysplastic Syndrome; Secondary Myelodysplastic Syndrome; Therapy-Related Myelodysplastic Syndrome
University of California, Davis
2017-12-01 PHASE1
NCT03118466 COMPLETED
AML
Massachusetts General Hospital
2017-09-25 PHASE2
NCT03785184 WITHDRAWN
Multiple Myeloma
AbbVie
2019-04-29 PHASE2
NCT02612779 COMPLETED
Multiple Myeloma
Bristol-Myers Squibb
2016-02-09 PHASE2
NCT02336815 COMPLETED
Multiple Myeloma
Karyopharm Therapeutics Inc
2015-05-26 PHASE2
NCT02280525 COMPLETED
Leukemia
M.D. Anderson Cancer Center
2015-03-05 PHASE1
NCT01858558 COMPLETED
Multiple Myeloma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2013-09 PHASE2
NCT03242460 COMPLETED
Relapsed and/or refractorY Multiple Myeloma
Kosin University Gospel Hospital
2015-05-12 PHASE2
NCT03558750 TERMINATED
Recurrent Central Nervous System Lymphoma; Recurrent Diffuse Large B-Cell Lymphoma; Refractory Central Nervous System Lymphoma; Refractory Diffuse Large B-Cell Lymphoma
Vanderbilt-Ingram Cancer Center
2018-06-14 PHASE1
NCT02705638 COMPLETED
Immunoglobulin G Subclass 4 Related Disease; IgG4-related Disease; Autoimmune Pancreatitis; IgG4-related Sclerosing Cholangitis; Retroperitoneal Fibrosis
Mayo Clinic
2016-04 PHASE1
NCT02285062 COMPLETED
Lymphoma, Large B-Cell, Diffuse
Celgene
2015-02-17 PHASE3
NCT01936532 COMPLETED
Newly Diagnosed Multiple Myeloma
Nantes University Hospital
2014-11-12 PHASE2
NCT01440582 COMPLETED
Myeloma
M.D. Anderson Cancer Center
2013-02-18 PHASE1
NCT04272775 TERMINATED
Relapsed and/or Refractory Multiple Myeloma
Takeda
2012-06-05 PHASE1
NCT01125176 COMPLETED
Chronic Lymphocytic Leukemia
Weill Medical College of Cornell University
2012-03-30 PHASE2
NCT01003769 TERMINATED
Recurrent Chronic Lymphocytic Leukemia
Mayo Clinic
2015-07-09 PHASE1; PHASE2
NCT02279394 COMPLETED
Smoldering Myeloma; Smoldering Multiple Myeloma
Dana-Farber Cancer Institute
2014-12-11 PHASE2
NCT02986451 WITHDRAWN
Relapse/Refractory Multiple Myeloma
Sun Yat-sen University
2016-12 PHASE2
NCT02371577 WITHDRAWN
Chronic Lymphocytic Leukemia (CLL)
University of California, San Diego
2017-02-01 PHASE2
NCT02128061 COMPLETED
Diffuse Large B Cell Lymphoma
The Lymphoma Academic Research Organisation
2014-08 PHASE3
NCT01638936 COMPLETED
Multiple Myeloma
Biotest Pharmaceuticals Corporation
2012-07-03 PHASE1; PHASE2
NCT02898259 TERMINATED
B Cell Lymphoma; Lymphoma
Brian Hill
2017-02-20 PHASE1; PHASE2
NCT01729104 TERMINATED
Lymphoma
M.D. Anderson Cancer Center
2013-04-25 PHASE1
NCT02928419 TERMINATED
Myelodysplastic Syndromes
Associazione Qol-one
2015-05 PHASE2
NCT03333746 TERMINATED
Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma
Yvonne Efebera
2018-03-21 PHASE2
NCT01582776 COMPLETED
Follicular Lymphoma Patients (Phase IB); Follicular and Agressive (DLBCL&MCL) B-cell Lymphoma Patients (Phase II)
The Lymphoma Academic Research Organisation
2012-10-03 PHASE1; PHASE2
NCT02579863 TERMINATED
Multiple Myeloma
Merck Sharp & Dohme LLC
2015-10-19 PHASE3
NCT00875667 COMPLETED
Mantle Cell Lymphoma; Lymphoma, Mantle-Cell
Celgene
2009-04-30 PHASE2
NCT01433965 COMPLETED
Acute Myeloid Leukemia; Myelodysplastic Syndrome
University of California, Davis
2012-08-08 PHASE1
NCT01816971 COMPLETED
Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma
University of Chicago
2013-01 PHASE2
NCT00352794 COMPLETED
Myelofibrosis
M.D. Anderson Cancer Center
2006-07-07 PHASE2
NCT01553786 COMPLETED
T-cell Lymphoma
The Lymphoma Academic Research Organisation
2011-11 PHASE2
NCT02158702 UNKNOWN
Multiple Myeloma; Relapse After Use of Lenalidomide and Bortezomib
National University Hospital, Singapore
2014-11 PHASE2
NCT02206425 COMPLETED
Multiple Myeloma
Oncotherapeutics
2014-09 PHASE1; PHASE2
NCT02389543 WITHDRAWN
Multiple Myeloma
Karyopharm Therapeutics Inc
2015-07 PHASE1; PHASE2
NCT01076543 COMPLETED
AIDS-Related Hodgkin Lymphoma; Recurrent Adult Hodgkin Lymphoma; Recurrent Follicular Lymphoma; Recurrent Lymphoplasmacytic Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent T-Cell Non-Hodgkin Lymphoma; Waldenstrom Macroglobulinemia
National Cancer Institute (NCI)
2010-04-15 PHASE1; PHASE2
NCT01270932 COMPLETED
Renal Failure; Multiple Myeloma
University Health Network, Toronto
2010-11 PHASE2
NCT02685826 COMPLETED
Multiple Myeloma
Celgene
2016-04-25 PHASE1; PHASE2
NCT02963610 TERMINATED
Relapsed or Refractory Solid Tumors; Nonsmall Cell Lung Cancer
Fox Chase Cancer Center
2017-03-29 PHASE1; PHASE2
NCT01939327 COMPLETED
Non-Hodgkin Lymphoma
Institut Paoli-Calmettes
2013-09 PHASE2
NCT02406144 COMPLETED
Multiple Myeloma
PETHEMA Foundation
2014-11 PHASE3
NCT03191981 WITHDRAWN
Myeloma Multiple
University of Leeds
2017-08-01 PHASE1; PHASE2
NCT00963534 COMPLETED
Mantle Cell Lymphoma
Lund University Hospital
2009-09 PHASE1; PHASE2
NCT02142049 COMPLETED
Diffuse Large B Cell Lymphoma Relapsed; Diffuse Large B Cell Lymphoma Refractory
Pharmacyclics LLC.
2014-05 PHASE1; PHASE2
NCT02538965 COMPLETED
Leukemia, Myeloid
Celgene
2015-11-19 PHASE2
NCT02655458 COMPLETED
Multiple Myeloma
Hearn Jay Cho
2016-01 PHASE1
NCT00891384 COMPLETED
Multiple Myeloma
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH
2009-04-01 PHASE3
NCT02086604 COMPLETED
Lymphoma, Large B-Cell, Diffuse
Washington University School of Medicine
2014-09-18 PHASE1
NCT01460420 COMPLETED
Hematologic Malignancies; Multiple Myeloma
European Myeloma Network B.V.
2011-11 PHASE1; PHASE2
NCT01731886 COMPLETED
Multiple Myeloma
Columbia University
2012-09 PHASE4
NCT03000634 WITHDRAWN
Multiple Myeloma
University of Arkansas
2017-04-01 PHASE2
NCT02200848 TERMINATED
Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma
Georgetown University
2014-04 PHASE1
NCT01924169 TERMINATED
Hematologic Disorder
M.D. Anderson Cancer Center
2014-11-24 PHASE2
NCT01352962 COMPLETED
Urethral Neoplasms; Neoplasms, Urethral; Cancer of the Urethra; Urethral Cancer
National Cancer Institute (NCI)
2011-09-26 PHASE1
NCT01109004 COMPLETED
Multiple Myeloma
National Heart, Lung, and Blood Institute (NHLBI)
2010-05 PHASE3
NCT02446236 ACTIVE_NOT_RECRUITING
Mantle Cell Lymphoma
Hackensack Meridian Health
2015-06-18 PHASE1
NCT01518465 TERMINATED
Stage I Multiple Myeloma; Stage II Multiple Myeloma; Stage III Multiple Myeloma
University of Southern California
2012-01-09 PHASE2
NCT01827137 COMPLETED
Multiple Myeloma
Sellas Life Sciences Group
2013-04 PHASE1; PHASE2
NCT01133743 COMPLETED
Chronic Lymphocytic Leukemia
University Health Network, Toronto
2010-05 PHASE2
NCT01460940 COMPLETED
Adult Lymphocyte Depletion Hodgkin Lymphoma; Adult Lymphocyte Predominant Hodgkin Lymphoma; Adult Mixed Cellularity Hodgkin Lymphoma; Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma; Adult Nodular Sclerosis Hodgkin Lymphoma; Recurrent Adult Hodgkin Lymphoma
Ohio State University Comprehensive Cancer Center
2011-10-13 PHASE2
NCT01794039 COMPLETED
Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma
Mayo Clinic
2014-03 PHASE2
NCT01545804 COMPLETED
Liver Cancer
National Taiwan University Hospital
2011-08 PHASE2
NCT01349569 COMPLETED
Multiple Myeloma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2012-01 PHASE2
NCT02348528 COMPLETED
Multiple Myeloma
Celgene
2012-09-11 PHASE2
NCT00540007 COMPLETED
Hodgkin Disease
Washington University School of Medicine
2007-09-06 PHASE2
NCT02340936 COMPLETED
Diffuse Large B-cell Lymphoma
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
2011-01 PHASE1; PHASE2
NCT01559935 COMPLETED
Multiple Myeloma
Weill Medical College of Cornell University
2012-04-19 PHASE2
NCT01578954 COMPLETED
Acute Myeloid Leukemia
UNC Lineberger Comprehensive Cancer Center
2012-06-28 PHASE1
NCT01675141 TERMINATED
Multiple Myeloma
National Cancer Institute (NCI)
2012-08-20 PHASE2
NCT00874978 COMPLETED
Myelodysplastic Syndromes
King's College Hospital NHS Trust
2005-01 PHASE2
NCT01183663 COMPLETED
Advanced Cancers
M.D. Anderson Cancer Center
2010-08 PHASE1
NCT00737529 COMPLETED
Mantle Cell Lymphoma
Celgene
2008-12-22 PHASE2
NCT01861340 COMPLETED
Myeloma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2014-05 EARLY_PHASE1
NCT01359657 COMPLETED
Multiple Myeloma
Bristol-Myers Squibb
2011-09 PHASE1
NCT01556776 COMPLETED
Chronic Lymphocytic Leukemia
German CLL Study Group
2012-07-20 PHASE3
NCT00294632 COMPLETED
Lymphoma
M.D. Anderson Cancer Center
2006-02 PHASE1; PHASE2
NCT00727415 COMPLETED
Chronic Lymphocytic Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto
2008-02 PHASE1; PHASE2
NCT01450215 COMPLETED
Multiple Myeloma
Karolinska University Hospital
2011-03 PHASE2
NCT00933426 TERMINATED
Prostate Cancer
M.D. Anderson Cancer Center
2009-08 PHASE1
NCT01215344 COMPLETED
Multiple Myeloma
Vanderbilt-Ingram Cancer Center
2010-11 PHASE2
NCT02075021 TERMINATED
Relapsed or Refractory Multiple Myeloma
NYU Langone Health
2014-03 PHASE1; PHASE2
NCT01673308 UNKNOWN
Myelodysplastic Syndrome
Ulsan University Hospital
2012-08 PHASE2
NCT01629082 COMPLETED
Myeldysplastic Syndrome (MDS); Chronic Myelomonocytic Leukemia; Bone Marrow Diseases; Neutropenia; Acute Myeloid Leukemia (AML)
National Heart, Lung, and Blood Institute (NHLBI)
2012-06-06 PHASE1
NCT01615029 COMPLETED
Multiple Myeloma
Janssen Research & Development, LLC
2012-06-26 PHASE1; PHASE2
NCT01816620 COMPLETED
POEMS Syndrome
Peking Union Medical College Hospital
2014-03 PHASE2
NCT02193698 COMPLETED
POEMS Syndrome
Chiba University
2014-07 PHASE2
NCT00632359 COMPLETED
Chronic Lymphocytic Leukemia
M.D. Anderson Cancer Center
2008-02 PHASE2
NCT02521714 COMPLETED
Healthy Volunteers
Celgene
2015-08-14 PHASE1
NCT01985477 TERMINATED
Myeloma
M.D. Anderson Cancer Center
2013-12 PHASE1
NCT01412307 UNKNOWN
Recurrent Adult Hodgkin Lymphoma
Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale
2011-07 PHASE1; PHASE2
NCT01647165 WITHDRAWN
Multiple Myeloma
National Cancer Institute (NCI)
2012-07-11 PHASE2
NCT00096044 COMPLETED
Leukemia
Roswell Park Cancer Institute
2004-03 PHASE2
NCT01358734 COMPLETED
Acute Myeloid Leukemia; Acute Myelogenous Leukemia
Celgene
2012-04-27 PHASE2
NCT01093183 TERMINATED
Adenocarcinoma of the Prostate; Hormone-resistant Prostate Cancer; Recurrent Prostate Cancer
University of Nebraska
2010-03-04 PHASE1; PHASE2
NCT01904643 TERMINATED
Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia
Stanford University
2014-02 PHASE1
NCT01368757 UNKNOWN
Chronic Myelomonocytic Leukemia
Arbeitsgemeinschaft medikamentoese Tumortherapie
2010-06 PHASE1; PHASE2
NCT00957385 COMPLETED
Acute Myeloid Leukemia
University Health Network, Toronto
2008-06 PHASE2
NCT02206503 COMPLETED
Multiple Myeloma
Fondazione EMN Italy Onlus
2013-03 PHASE2
NCT01617213 TERMINATED
Multiple Myeloma
University of Virginia
2012-04 PHASE2
NCT01604031 TERMINATED
B-cell Chronic Lymphocytic Leukemia
Baylor College of Medicine
2013-02 PHASE1
NCT01703364 COMPLETED
CLL; Chronic Lymphocytic Leukemia
Arbeitsgemeinschaft medikamentoese Tumortherapie
2012-06 PHASE1; PHASE2
NCT01373294 COMPLETED
Bladder Cancer
H. Lee Moffitt Cancer Center and Research Institute
2011-11-30 PHASE2
NCT02525250 COMPLETED
Acute Myeloid Leukemia or Myelodysplasic Syndrome
Institut Paoli-Calmettes
2012-12
NCT01403246 TERMINATED
Chronic Lymphocytic Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto
2011-11 PHASE1; PHASE2
NCT02038153 TERMINATED
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Adult Acute Myeloid Leukemia in Remission
Albert Einstein College of Medicine
2013-12 PHASE1; PHASE2
NCT01111903 COMPLETED
Ovarian Cancer Recurrent
ARCAGY/ GINECO GROUP
2009-05 PHASE1; PHASE2
NCT00466895 COMPLETED
Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia; Chronic Lymphocytic Leukemia
Leslie Andritsos
2007-04 PHASE1
NCT01241734 COMPLETED
Diffuse Large B Cell Lymphoma
Hackensack Meridian Health
2010-10 PHASE1; PHASE2
NCT00765245 COMPLETED
Lymphoma
Vanderbilt-Ingram Cancer Center
2008-10 PHASE2
NCT01352338 COMPLETED
Multiple Myeloma
UMC Utrecht
2011-08 PHASE1; PHASE2
NCT00864942 COMPLETED
Chronic Lymphocytic Leukemia; Non-Hodgkin's Lymphoma
Georgetown University
2009-02 PHASE1
NCT01239797 COMPLETED
Lymphoma; Multiple Myeloma
Bristol-Myers Squibb
2011-06-20 PHASE3
NCT01704781 COMPLETED
HIV-1 Infection
Bionor Immuno AS
2012-09 PHASE1; PHASE2
NCT01644799 COMPLETED
Recurrent Follicular Lymphoma
Alliance for Clinical Trials in Oncology
2013-08-02 PHASE1
NCT01645930 COMPLETED
Multiple Myeloma
Millennium Pharmaceuticals, Inc.
2012-12-17 PHASE1
NCT00759603 COMPLETED
Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma
M.D. Anderson Cancer Center
2008-09 PHASE2
NCT01737177 COMPLETED
Mantle Cell Lymphoma
Fondazione Italiana Linfomi - ETS
2012-07-31 PHASE2
NCT01484626 TERMINATED
Multiple Myeloma
Loyola University
2011-05-05 PHASE1; PHASE2
NCT01080391 COMPLETED
Relapsed Multiple Myeloma
Amgen
2010-07-14 PHASE3
NCT01246076 COMPLETED
Myelodysplastic Syndromes
Washington University School of Medicine
2011-06 PHASE2
NCT00902915 UNKNOWN
Multiple Myeloma Light Chain Induced Renal Insufficiency
Austrian Forum Against Cancer
2009-05 PHASE2
NCT00867308 TERMINATED
Myelodysplastic Syndrome
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2009-07 PHASE2
NCT01472562 COMPLETED
Mantle Cell Lymphoma
Weill Medical College of Cornell University
2011-07-29 PHASE2
NCT00910910 COMPLETED
B-Cell Chronic Lymphocytic Leukemia
Celgene
2009-10-13 PHASE3
NCT01393964 COMPLETED
Multiple Myeloma
Bristol-Myers Squibb
2012-01-06 PHASE1
NCT00915408 COMPLETED
Multiple Myeloma
King's College Hospital NHS Trust
2006-09 PHASE1; PHASE2
NCT01537861 TERMINATED
Multiple Myeloma
Washington University School of Medicine
2012-06 EARLY_PHASE1
NCT01282047 TERMINATED
HIV Infection Associated Kaposi Disease
French National Agency for Research on AIDS and Viral Hepatitis
2011-10 PHASE2
NCT00671801 TERMINATED
Malignant Gliomas
M.D. Anderson Cancer Center
2008-04-29 PHASE1
NCT01254617 COMPLETED
Recurrent Colon Carcinoma; Recurrent Hypopharyngeal Squamous Cell Carcinoma; Recurrent Laryngeal Squamous Cell Carcinoma; Recurrent Laryngeal Verrucous Carcinoma; Recurrent Lip and Oral Cavity Squamous Cell Carcinoma; Recurrent Metastatic Squamous Cell Carcinoma in the Neck With Occult Primary; Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma; Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma; Recurrent Oral Cavity Verrucous Carcinoma; Recurrent Oropharyngeal Squamous Cell Carcinoma; Recurrent Rectal Carcinoma; Recurrent Salivary Gland Carcinoma; Salivary Gland Squamous Cell Carcinoma; Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary; Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7; Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7; Stage IVA Colon Cancer AJCC v7; Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7; Stage IVA Laryngeal Verrucous Carcinoma AJCC v7; Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7; Stage IVA Major Salivary Gland Cancer AJCC v7; Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7; Stage IVA Oral Cavity Cancer AJCC v6 and v7; Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7; Stage IVA Rectal Cancer AJCC v7; Stage IVB Colon Cancer AJCC v7; Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7; Stage IVB Laryngeal Verrucous Carcinoma AJCC v7; Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7; Stage IVB Major Salivary Gland Cancer AJCC v7; Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7; Stage IVB Oral Cavity Cancer AJCC v6 and v7; Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7; Stage IVB Rectal Cancer AJCC v7; Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7; Stage IVC Laryngeal Verrucous Carcinoma AJCC v7; Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7; Stage IVC Major Salivary Gland Cancer AJCC v7; Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7; Stage IVC Oral Cavity Cancer AJCC v6 and v7; Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7; Tongue Carcinoma
National Cancer Institute (NCI)
2011-02-10 PHASE1
NCT02983097 TERMINATED
Diffuse Large B-cell Lymphoma (DLBCL); Follicular Lymphoma Grade III (FL III°); Mantle Cell Lymphoma (MCL), Blastoid Variant; Burkitt Lymphoma (BL); Aggressive Marginal Zone Lymphoma (MZL)
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH
2010-11 PHASE1; PHASE2
NCT01132586 COMPLETED
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11; Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11; Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1; Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL; Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA; Alkylating Agent-Related Acute Myeloid Leukemia; de Novo Myelodysplastic Syndrome; Previously Treated Myelodysplastic Syndrome; Recurrent Adult Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndrome; Untreated Adult Acute Myeloid Leukemia
National Cancer Institute (NCI)
2010-05 PHASE1
NCT01547260 COMPLETED
Pancreatic Carcinoma Metastatic; Pancreatic Ductal Adenocarcinoma
Maria Liljefors
2009-10 PHASE1; PHASE2
NCT01019174 COMPLETED
Multiple Myeloma
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH
2009-11 PHASE1; PHASE2
NCT01217203 COMPLETED
Patients With Multiple Myeloma Experiencing a; First or Second Relapse
Innate Pharma
2010-09 PHASE1
NCT01698801 COMPLETED
Multiple Myeloma
Celgene
2012-10-01 PHASE2
NCT00622336 COMPLETED
Multiple Myeloma
Celgene
2003-04-01 PHASE3
NCT01379274 TERMINATED
MDS
Rush University Medical Center
2011-01 PHASE2
NCT01465230 TERMINATED
Chronic Lymphocytic Leukemia
Yale University
2012-03 PHASE2
NCT01558167 COMPLETED
Chronic Lymphocytic Leukemia
German CLL Study Group
2011-02 PHASE1; PHASE2
NCT00784927 COMPLETED
Lymphoma
Mayo Clinic
2008-11 PHASE2
NCT01378091 COMPLETED
Prostate Cancer
Columbia University
2005-08 PHASE1
NCT01197560 COMPLETED
Diffuse Large B-cell Lymphoma
Celgene
2010-09-02 PHASE2; PHASE3
NCT01200004 TERMINATED
Advanced Cancers
M.D. Anderson Cancer Center
2012-04 PHASE1
NCT01393756 COMPLETED
Follicular Lymphoma
The Lymphoma Academic Research Organisation
2010-12 PHASE2
NCT00603447 COMPLETED
Relapsed Multiple Myeloma
Amgen
2008-05 PHASE1
NCT00617591 COMPLETED
Multiple Myeloma
H. Lee Moffitt Cancer Center and Research Institute
2008-01 PHASE2
NCT00536341 COMPLETED
Chronic Lymphocytic Leukemia
SCRI Development Innovations, LLC
2008-01 PHASE1; PHASE2
NCT01348919 COMPLETED
Multiple Myeloma
Teva Branded Pharmaceutical Products R&D, Inc.
2011-08-03 PHASE1; PHASE2
NCT01217957 COMPLETED
Multiple Myeloma
Millennium Pharmaceuticals, Inc.
2010-11-22 PHASE1; PHASE2
NCT01121757 TERMINATED
Follicular Lymphoma; Marginal Zone Lymphoma
Duke University
2010-04 PHASE2
NCT00735930 COMPLETED
Anemia; Chronic Lymphocytic Leukemia; Prolymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Thrombocytopenia
National Cancer Institute (NCI)
2008-08 PHASE1
NCT00535873 COMPLETED
Leukemia; CLL; Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma
M.D. Anderson Cancer Center
2007-10 PHASE2
NCT01422486 TERMINATED
Myelodysplastic Syndrome (MDS)
Telik
2011-10 PHASE2
NCT00114101 ACTIVE_NOT_RECRUITING
DS Stage I Multiple Myeloma; DS Stage II Multiple Myeloma; DS Stage III Multiple Myeloma; Refractory Multiple Myeloma; Smoldering Multiple Myeloma
National Cancer Institute (NCI)
2004-12-15 PHASE3
NCT01145495 COMPLETED
Ann Arbor Stage II Grade 1 Contiguous Follicular Lymphoma; Ann Arbor Stage II Grade 1 Non-Contiguous Follicular Lymphoma; Ann Arbor Stage II Grade 2 Contiguous Follicular Lymphoma; Ann Arbor Stage II Grade 2 Non-Contiguous Follicular Lymphoma; Ann Arbor Stage II Grade 3 Contiguous Follicular Lymphoma; Ann Arbor Stage II Grade 3 Non-Contiguous Follicular Lymphoma; Ann Arbor Stage III Grade 1 Follicular Lymphoma; Ann Arbor Stage III Grade 2 Follicular Lymphoma; Ann Arbor Stage III Grade 3 Follicular Lymphoma; Ann Arbor Stage IV Grade 1 Follicular Lymphoma; Ann Arbor Stage IV Grade 2 Follicular Lymphoma; Ann Arbor Stage IV Grade 3 Follicular Lymphoma
National Cancer Institute (NCI)
2010-06-15 PHASE2
NCT01185262 COMPLETED
Chronic Lymphocytic Leukemia
MD Anderson International Spain SA
2009-04 PHASE1
NCT00691704 COMPLETED
Multiple Myeloma
Cristina Gasparetto
2008-08 PHASE2
NCT01348503 TERMINATED
Hepatocellular Carcinoma
Indiana University
2011-05 PHASE1
NCT00495872 COMPLETED
Solid Tumors
M.D. Anderson Cancer Center
2007-06 PHASE1
NCT00642954 COMPLETED
Relapsed or Refractory Multiple Myeloma
Merck Sharp & Dohme LLC
2008-02-13 PHASE1
NCT01127386 COMPLETED
Cancer Cachexia Syndrome
Florian Strasser, MD ABHPM
2009-03 PHASE1; PHASE2
NCT01194791 COMPLETED
Primary Systemic Amyloidosis
PETHEMA Foundation
2010-10 PHASE2
NCT00654186 COMPLETED
Prostate Cancer
Oncology Specialists, S.C.
2008-02 PHASE2
NCT00972842 TERMINATED
Peripheral T-Cell Non-Hodgkin's Lymphoma
Arbeitsgemeinschaft medikamentoese Tumortherapie
2009-09 PHASE1; PHASE2
NCT00091260 COMPLETED
Multiple Myeloma
Vaishali Sanchorawala
2004-01 PHASE2
NCT00360672 COMPLETED
Acute Myelogenous Leukemia; Myelodysplastic Syndrome
M.D. Anderson Cancer Center
2009-01 PHASE2
NCT00884546 COMPLETED
Advanced Cancer, Various, NOS
Bristol-Myers Squibb
2009-07 PHASE1
NCT01501370 WITHDRAWN
Multiple Myeloma
Tiziana Marangon
2012-01 PHASE2
NCT01029054 COMPLETED
Multiple Myeloma
University of Michigan Rogel Cancer Center
2009-09 PHASE1; PHASE2
NCT00975806 TERMINATED
Renal Cell Carcinoma
Celgene
2009-09-01 PHASE1; PHASE2
NCT02353468 TERMINATED
Refractory Plasma Cell Myeloma
University of Colorado, Denver
2009-12 PHASE2
NCT00352001 COMPLETED
Leukemia; Myelodysplastic Syndromes
Mikkael Sekeres MD
2006-05 PHASE1; PHASE2
NCT01166035 UNKNOWN
Solid Tumors
Medical University Innsbruck
2010-03 PHASE1; PHASE2
NCT01271283 WITHDRAWN
Chronic Lymphocytic Leukemia; Stage III Chronic Lymphocytic Leukemia; Stage IV Chronic Lymphocytic Leukemia
National Cancer Institute (NCI)
2010-12 PHASE2
NCT00903630 TERMINATED
Fallopian Tube Cancer; Ovarian Cancer; Peritoneal Cavity Cancer
Masonic Cancer Center, University of Minnesota
2009-04 PHASE1; PHASE2
NCT01055301 WITHDRAWN
Multiple Myeloma; Plasma Cell Myeloma
SWOG Cancer Research Network
2011-07 PHASE2
NCT00923663 UNKNOWN
MALT Lymphoma
Medical University of Vienna
2009-07 PHASE2
NCT00890929 COMPLETED
Acute Myeloid Leukemia (AML); Adult Acute Myeloblastic Leukemia
Stanford University
2009-04 PHASE1; PHASE2
NCT00665652 TERMINATED
Neuropathy; Nonmalignant Monoclonal Gammopathy of Undetermined Significance (MGUS)
Dartmouth-Hitchcock Medical Center
2008-04 PHASE2
NCT01180569 WITHDRAWN
Lymphoma; Follicular Lymphoma
Memorial Sloan Kettering Cancer Center
2010-08 PHASE1; PHASE2
NCT00413036 COMPLETED
Lymphoma, Non-Hodgkin's
Celgene
2006-06 PHASE2
NCT00860457 COMPLETED
Chronic Lymphocytic Leukemia
Georgetown University
2008-02 PHASE2
NCT01045928 TERMINATED
Adult Non-Hodgkin Lymphoma; Adult Grade III Lymphomatoid Granulomatosis; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Small Lymphocytic Lymphoma; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Waldenstrom Macroglobulinemia
Case Comprehensive Cancer Center
2010-01 PHASE1
NCT00981708 COMPLETED
Amyloidosis
University of Athens
2008-02 PHASE1; PHASE2
NCT02041325 COMPLETED
Plasma Cell Disorder
Boston VA Research Institute, Inc.
2005-04 PHASE2
NCT00699842 TERMINATED
Myelodysplastic Syndrome; MDS; Low to Intermediate-1 MDS; Non-deletion 5q
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
2008-07 PHASE1; PHASE2
NCT00907452 COMPLETED
Myeloma
Intergroupe Francophone du Myelome
2009-07-29
NCT00840827 TERMINATED
Myelodysplastic Syndrome
Weill Medical College of Cornell University
2008-12 PHASE2
NCT00602836 COMPLETED
Leukemia; Lymphoma
Mayo Clinic
2008-02 PHASE2
NCT00227591 COMPLETED
Essential Thrombocythemia; Polycythemia Vera; Primary Myelofibrosis
National Cancer Institute (NCI)
2005-12 PHASE2
NCT00460031 COMPLETED
Prostate Cancer
Case Comprehensive Cancer Center
2006-09-01 PHASE2
NCT00482261 COMPLETED
Multiple Myeloma
Peter MacCallum Cancer Centre, Australia
2007-06 PHASE2
NCT01408199 COMPLETED
Cutaneous Lupus
Hospital Universitari Vall d'Hebron Research Institute
2010-01 PHASE4
NCT00287287 COMPLETED
Thyroid Neoplasms
Kenneth Ain
2006-02 PHASE2
NCT00538733 COMPLETED
Multiple Myeloma
Weill Medical College of Cornell University
2007-10 PHASE2
NCT01222195 TERMINATED
Leukemia
M.D. Anderson Cancer Center
2008-02 PHASE2
NCT00786851 COMPLETED
MANTLE CELL LYMPHOMA
Fondazione Italiana Linfomi - ETS
2008-07 PHASE2
NCT01116154 TERMINATED
Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Peripheral T-Cell Lymphoma; Post-transplant Lymphoproliferative Disorder; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Testicular Lymphoma; Waldenstrom Macroglobulinemia
City of Hope Medical Center
2010-05 PHASE1
NCT00837031 COMPLETED
Metastatic Pancreatic Cancer
SCRI Development Innovations, LLC
2009-02 PHASE2
NCT00525447 COMPLETED
Multiple Myeloma
Seagen Inc.
2007-08 PHASE1
NCT00968331 TERMINATED
Diffuse Large B-cell Lymphoma
University of Bologna
2009-03 PHASE2
NCT00761449 COMPLETED
MDS; AML
Nordic MDS Group
2007-10 PHASE2
NCT00621400 COMPLETED
Amyloidosis
Nantes University Hospital
2008-01 PHASE1; PHASE2
NCT00729638 COMPLETED
Multiple Myeloma
Massachusetts General Hospital
2008-06 PHASE1
NCT00633945 COMPLETED
Cutaneous Lupus Erythematosus (CLE)
University of Pennsylvania
2007-11
NCT00704691 TERMINATED
Peripheral T-cell Lymphomas; Adult T-cell Leukemia; Adult T-cell Lymphoma; Peripheral T-cell Lymphoma Unspecified; Angioimmunoblastic T-cell Lymphoma; Anaplastic Large Cell Lymphoma; T/Null Cell Systemic Type; Cutaneous t-Cell Lymphoma With Nodal/Visceral Disease
University of Alabama at Birmingham
2008-06 EARLY_PHASE1
NCT00104962 COMPLETED
Childhood Myelodysplastic Syndromes; de Novo Myelodysplastic Syndromes; Previously Treated Myelodysplastic Syndromes; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Ringed Sideroblasts; Refractory Cytopenia With Multilineage Dysplasia; Secondary Myelodysplastic Syndromes; Unspecified Childhood Solid Tumor, Protocol Specific
National Cancer Institute (NCI)
2005-03 PHASE1
NCT00445484 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2007-01 PHASE2
NCT00109005 COMPLETED
Melanoma
National Cancer Institute (NCI)
2005-04 PHASE2
NCT00418665 COMPLETED
Myelodysplastic Syndromes; Thrombocytopenia
Amgen
2006-12 PHASE2
NCT00564889 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
Mayo Clinic
2007-12 PHASE2
NCT00474188 TERMINATED
Diffuse Large B-cell Lymphoma
Celgene Corporation
2007-05 PHASE2
NCT00305812 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
NCIC Clinical Trials Group
2006-03-09 PHASE2
NCT00179660 COMPLETED
Non-Hodgkins Lymphoma
Celgene Corporation
2005-08 PHASE2
NCT00477750 COMPLETED
Multiple Myeloma and Plasma Cell Neoplasm
Mayo Clinic
2005-06 PHASE1; PHASE2
NCT00179673 COMPLETED
Non-Hodgkins Lymphoma
Celgene
2005-06 PHASE2
NCT00109772 TERMINATED
Complex Regional Pain Syndrome, Type I
Celgene Corporation
2005-02 PHASE2
NCT00961467 COMPLETED
Multiple Myeloma
Fondazione EMN Italy Onlus
2007-02 PHASE2
NCT00412581 COMPLETED
Melanoma
M.D. Anderson Cancer Center
2005-09 PHASE1
NCT00031941 COMPLETED
Lymphoma; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific
National Institutes of Health Clinical Center (CC)
2002-04 PHASE1
NCT00046735 COMPLETED
Neoplasms
Celgene
2002-06-01 PHASE1
NCT00142168 TERMINATED
Waldenstrom's Macroglobulinemia
Dana-Farber Cancer Institute
2004-09 PHASE2
NCT00096525 COMPLETED
Kidney Cancer
Memorial Sloan Kettering Cancer Center
2004-07 PHASE2
NCT00925821 COMPLETED
Multiple Myeloma
Wuerzburg University Hospital
2009-06 PHASE2
NCT00179686 COMPLETED
Non-Small Cell Lung Cancer
Celgene Corporation
2005-03 PHASE2
NCT00424229 UNKNOWN
Myelodysplastic Syndromes
Groupe Francophone des Myelodysplasies
2006-10 PHASE2
NCT00833534 WITHDRAWN
Leukemia; Lymphoma
Fred Hutchinson Cancer Center
2009-02 PHASE2
NCT01127542 TERMINATED
Chronic Lymphocytic Leukaemia
The Christie NHS Foundation Trust
2010-05 PHASE2
NCT00179751 TERMINATED
Pancreatic Cancer
Celgene Corporation
2005-04 PHASE1; PHASE2

(data from https://clinicaltrials.gov, updated on 2026-06-18)

Check the CC-5013 (Lenalidomide) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Lenalidomide binds to cereblon within the CRL4 ubiquitin ligase complex, driving the selective polyubiquitination and proteasomal degradation of lymphoid transcription factors IKZF1 and IKZF3 while suppressing tumor necrosis factor-alpha secretion. This molecular targeting downregulates vascular endothelial growth factor expression to induce G1 cell cycle arrest and apoptosis, providing clinical efficacy against hematologic malignancies including multiple myeloma and diffuse large B-cell lymphoma.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.