For research use only. Not for use in humans.

Latozinemab (Anti-Sortilin / SORT1)

Synonyms: AL001 Cat.No.A2920 Purity:99%

Latozinemab (anti-Sortilin / SORT1) is a recombinant humanized anti-Sortilin monoclonal antibody. Latozinemab has the potential for progranulin gene (GRN) mutations causative of frontotemporal dementia (FTD) (FTD-GRN) research. MW: 146.28 KD.

Quality Control

Batch: Purity: 99% Protein concentration: 6.711mg/ml Endotoxin Level: ＜1EU/mg

Mechanism of Action

Description	Latozinemab (anti-Sortilin / SORT1) is a recombinant humanized anti-Sortilin monoclonal antibody. Latozinemab has the potential for progranulin gene (GRN) mutations causative of frontotemporal dementia (FTD) (FTD-GRN) research. MW: 146.28 KD.
References	[1] https://n.neurology.org/content/96/15_Supplement/4422

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	2376132-27-1
Molecular Weight	146.28
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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