Larotrectinib (LOXO-101): Mechanism of Action

Larotrectinib (LOXO-101) MOA:Targeting TRK/MAPK Pathway for NTRK Fusion-Positive Solid Tumors

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Larotrectinib is a potent ATP-competitive TRK inhibitor. It affects ERK/AKT signaling by blocking TRK, inhibiting tumor growth.

Primary Applications and Mechanism of Action