CAS No. 73-22-3
Batch:
Purity:99.28
Chemical Structure
Check the
L-Tryptophan
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid | |
|---|---|---|
| CAS Number | 73-22-3 | |
| Molecular Formula |
C11H12N2O2 |
|
| Molecular Weight (MW) | 204.23 | |
| InChIKey | QIVBCDIJIAJPQS-VIFPVBQESA-N |
L-Tryptophan is an essential amino acid that serves as a substrate for serotonin, melatonin, and kynurenine pathway biosynthesis. Enzymatic conversion of L-tryptophan via tryptophan 5-hydroxylase and indoleamine 2,3-dioxygenase regulates neurotransmitter availability and systemic nitrogen balance. Downstream metabolism through the kynurenine pathway generates nicotinamide adenine dinucleotide, while serotonin and melatonin production modulate neurological, immune, and circadian signaling processes. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
11 mg/mL
(53.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.