CAS No. 642-38-6

Batch: Purity:98
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L-Quebrachitol Chemical Structure
Chemical Structure
Check the L-Quebrachitol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (1R,2S,4S,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol
CAS Number 642-38-6
Molecular Formula

C7H14O6
Molecular Weight (MW) 194.18
SMILES COC1C(O)C(O)C(O)C(O)C1O
InChIKey DSCFFEYYQKSRSV-MBXCVVGISA-N

Ordering Information

Biological Activity

L-Quebrachitol is a natural plant-derived compound that promotes cell proliferation and cell DNA synthesis. It upregulates bone morphogenetic protein-2 (BMP-2) and runt-related transcription factor-2 (Runx2), as well as key regulatory genes associated with the MAPK and Wnt/β-catenin signaling pathways. Concurrently, L-Quebrachitol downregulates receptor activator of nuclear factor-κB ligand (RANKL) mRNA expression levels to modulate cell differentiation. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 39 mg/mL (200.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 39 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.