SMILES:

OC(=O)C1=N[N](CCC2=CC=CC=C2)C=C1NC(=O)CSC3=CC=C(Br)C=C3
KR-33494 Chemical Structure
Chemical Structure
Check the KR-33494 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-[[2-(4-bromophenyl)sulfanylacetyl]amino]-1-(2-phenylethyl)pyrazole-3-carboxylic acid
CAS Number 1021497-97-1
Molecular Formula

C20H18BrN3O3S
Molecular Weight (MW) 460.34
SMILES OC(=O)C1=N[N](CCC2=CC=CC=C2)C=C1NC(=O)CSC3=CC=C(Br)C=C3
InChIKey ZRLJEHIUGYTTSZ-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 92 mg/mL (199.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.