Molecular Weight: 437.95 g/mol

(+)-JQ1 PA Chemical Structure
Chemical Structure
Check the (+)-JQ1 PA product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 88 mg/mL (200.93 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 88 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]-N-prop-2-ynylacetamide
CAS Number 2115701-93-2
Molecular Formula

C22H20ClN5OS
Molecular Weight (MW) 437.95
SMILES CC1=C(C)C2=C(S1)[N]3C(=NN=C3C(CC(=O)NCC#C)N=C2C4=CC=C(Cl)C=C4)C
InChIKey ZLSCJWMPQYKVKU-KRWDZBQOSA-N

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Note: Technical data last updated: Sep 1, 2026.