CAS No. 523-50-2
Batch:
Purity:99.91
Chemical Structure
Check the
Isopsoralen
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | furo[2,3-h]chromen-2-one | |
|---|---|---|
| CAS Number | 523-50-2 | |
| Molecular Formula |
C11H6O3 |
|
| Molecular Weight (MW) | 186.16 | |
| SMILES | C1=CC2=C(C=CO2)C3=C1C=CC(=O)O3 | |
| InChIKey | XDROKJSWHURZGO-UHFFFAOYSA-N |
Isopsoralen (angelicin) is a natural furanocoumarin constituent isolated from Angelica species that exhibits anti-inflammatory and antiviral activities. It modulates lipopolysaccharide-induced inflammatory responses through the regulation of MAPK and NF-κB signaling pathways, suppressing the downstream production of pro-inflammatory mediators. In addition, isopsoralen displays inhibitory activity against gammaherpesviruses, making it a useful chemical tool for investigating inflammatory signaling cascades and viral infection mechanisms. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
14 mg/mL
(75.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
9 mg/mL
(48.34 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.