CAS No. 537-73-5
Batch:
Purity:99.98
Chemical Structure
Check the
Isoferulic Acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 537-73-5 | |
|---|---|---|
| Molecular Formula |
C10H10O4 |
|
| Molecular Weight (MW) | 194.18 | |
| SMILES | COC1=C(C=C(C=C1)C=CC(=O)O)O |
Biological Activity
Isoferulic acid is a natural cinnamic acid derivative that acts as an agonist of alpha1-adrenergic receptors with antidiabetic, anti-inflammatory, and antioxidant activities. Activation of alpha1-adrenergic receptors by isoferulic acid stimulates the secretion of beta-endorphin, which enhances glucose utilization and uptake in skeletal muscle. This downstream signaling pathway lowers blood glucose levels and improves metabolic regulation in diabetic models.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
38 mg/mL
(195.69 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.