CAS No. 27975-19-5

Batch: Purity:98
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Iso-Steviol Chemical Structure
Chemical Structure
Check the Iso-Steviol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 27975-19-5
Molecular Formula

C20H30O3
Molecular Weight (MW) 318.45
SMILES CC12CCC3C4(CCCC(C4CCC3(C1)CC2=O)(C)C(=O)O)C

Ordering Information

Biological Activity

Iso-Steviol is a bioactive diterpenoid derivative possessing antioxidant, anti-inflammatory, and cardioprotective properties. It modulates cellular signaling pathways by suppressing nuclear factor-kappa B (NF-kB) activation and reducing reactive oxygen species (ROS) production, leading to downregulated expression of pro-inflammatory cytokines, including TNF-a and IL-6. Downstream, these cellular effects contribute to the attenuation of inflammatory cascades and protection against oxidative injury and cell death. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 63 mg/mL (197.83 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.