CAS No. 35212-22-7

Batch: Purity:99.74
Ipriflavone (Osteofix) Chemical Structure
Chemical Structure
Check the Ipriflavone (Osteofix) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 3-phenyl-7-propan-2-yloxychromen-4-one
CAS Number 35212-22-7
Molecular Formula

C18H16O3

Molecular Weight (MW) 280.32
InChIKey SFBODOKJTYAUCM-UHFFFAOYSA-N

Ordering Information

Biological Activity

Ipriflavone is a synthetic isoflavone derivative that acts as an inhibitor of bone resorption. It directly targets osteoclasts to suppress bone-resorbing activity while simultaneously promoting osteoblast proliferation and bone formation. Through these pathway-modulating effects, ipriflavone interferes with bone remodeling, reducing osteoclast numbers and preserving bone density in preclinical models of bone loss. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 56 mg/mL (199.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 2 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.