Home Biosimilar Antibodies Others Others Inclacumab (Anti-P-Selectin / CD62p)
For research use only. Not for use in humans.

Inclacumab (Anti-P-Selectin / CD62p)

Synonyms: SELP， CD62P

Inclacumab (Anti-P-Selectin / CD62p) is a humanized monoclonal IgG4 antibody selectively targets P-selectin. It reduces cell adhesion showing potential for prevention of sickle cell disease (SCD). MW :150 KD.

Inclacumab (Anti-P-Selectin / CD62p)

Quality Control

Batch: A261601 Purity: 99% Protein concentration: 4.04mg/ml Endotoxin Level: ＜1EU/mg
99

Mechanism of Action

Description
Inclacumab (Anti-P-Selectin / CD62p) is a humanized monoclonal IgG4 antibody selectively targets P-selectin. It reduces cell adhesion showing potential for prevention of sickle cell disease (SCD). MW :150 KD.
References

Product Details

CAS No. 1256258-86-2
Molecular Weight 150
Isotype Human IgG4SP
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05348915 TERMINATED Drug: Inclacumab Sickle Cell Disease; Vaso-occlusive Crisis; Vaso-occlusive Pain Episode in Sickle Cell Disease Pfizer 2022-03-29 PHASE3
NCT04935879 COMPLETED Drug: Inclacumab|Drug: Placebo Sickle Cell Disease; Vaso-occlusive Pain Episode in Sickle Cell Disease; Vaso-occlusive Crisis Pfizer 2021-10-04 PHASE3
NCT04927247 TERMINATED Drug: Inclacumab|Drug: Placebo Sickle Cell Disease; Vaso-occlusive Crisis; Vaso-occlusive Pain Episode in Sickle Cell Disease Pfizer 2021-12-09 PHASE3
NCT01815827 COMPLETED Drug: inclacumab Healthy Volunteer Hoffmann-La Roche 2013-06 PHASE1

(data from https://clinicaltrials.gov, updated on 2025-12-17)

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