Molecular Weight: 611.51 g/mol
Chemical Structure
Check the
Uzansertib (INCB053914)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
50 mg/mL
(81.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| IUPAC Name | N-[(7R)-4-[(3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl]-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-3-yl]-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide | |
|---|---|---|
| CAS Number | 2088852-47-3 | |
| Molecular Formula |
C26H26F3N5O3.H3O4P |
|
| Molecular Weight (MW) | 611.51 | |
| SMILES | CC1CN(CC(C1O)N)C2=C3CCC(C3=NC=C2NC(=O)C4=NC(=C(C=C4)F)C5=C(C=CC=C5F)F)O.OP(=O)(O)O | |
| InChIKey | PTORCEYGCGXHDH-OVMXCRKPSA-N |
- Uzansertib (INCB053914) Clinical Trials
- Uzansertib (INCB053914) Solubility in DMSO
- Uzansertib (INCB053914) Stock Solution
- Uzansertib (INCB053914) Storage
- Uzansertib (INCB053914) Stability
- Uzansertib (INCB053914) SMILES
- Uzansertib (INCB053914) CAS Number
- Uzansertib (INCB053914) Chemical Structure (2D and 3D)
- Uzansertib (INCB053914) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.