CAS No. 170105-16-5
Batch:
Purity:99.6
Chemical Structure
Check the
Imidafenacin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-(2-methylimidazol-1-yl)-2,2-diphenylbutanamide | |
|---|---|---|
| CAS Number | 170105-16-5 | |
| Molecular Formula |
C20H21N3O |
|
| Molecular Weight (MW) | 319.40 | |
| SMILES | CC1=NC=CN1CCC(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N | |
| InChIKey | SQKXYSGRELMAAU-UHFFFAOYSA-N |
Imidafenacin is a potent muscarinic receptor antagonist that selectively targets muscarinic M3 and M1 receptors over M2 receptors. By blocking muscarinic receptors in urinary bladder smooth muscle, it inhibits acetylcholine-induced bladder contractions and suppresses detrusor muscle overactivity. Consequently, imidafenacin effectively ameliorates bladder hyperactivity and increases voiding capacity in preclinical models of overactive bladder.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
63 mg/mL
(197.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.