Molecular Weight: 503.5 g/mol

IHMT-PI3Kδ-372 Chemical Structure
Chemical Structure
Check the IHMT-PI3Kδ-372 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 50 mg/mL (99.3 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 50 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name 2-[(1R)-1-[4-amino-3-(3-fluoro-4-methoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]propyl]-3-cyclopropyl-5-fluoroquinazolin-4-one
CAS Number 2429889-62-1
Molecular Formula

C26H23F2N7O2
Molecular Weight (MW) 503.5
SMILES CCC([N]1N=C(C2=CC=C(OC)C(=C2)F)C3=C(N)N=CN=C13)C4=NC5=C(C(=CC=C5)F)C(=O)N4C6CC6
InChIKey HTUBTEAYSCSTIY-GOSISDBHSA-N

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Note: Technical data last updated: Sep 1, 2026.