CAS No. 68-94-0

Batch: Purity:99.96
Hypoxanthine Chemical Structure
Chemical Structure
Check the Hypoxanthine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 1,7-dihydropurin-6-one
CAS Number 68-94-0
Molecular Formula

C5H4N4O

Molecular Weight (MW) 136.11
SMILES C1=NC2=C(N1)C(=O)NC=N2
InChIKey FDGQSTZJBFJUBT-UHFFFAOYSA-N

Ordering Information

Biological Activity

Hypoxanthine is a naturally occurring purine derivative and key metabolic intermediate in the purine salvage and catabolic pathways. It is converted to inosine monophosphate (IMP) by hypoxanthine-guanine phosphoribosyltransferase (HGPRT) and oxidized to xanthine and subsequently uric acid by xanthine oxidase. Through these pathways, hypoxanthine plays an essential role in nucleotide biosynthesis and purine homeostasis. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 7 mg/mL (51.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.