CAS No. 630-56-8

Batch: Purity:99.92
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Hydroxyprogesterone caproate Chemical Structure
Chemical Structure
Check the Hydroxyprogesterone caproate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 630-56-8
Molecular Formula

C27H40O4
Molecular Weight (MW) 428.60
SMILES CCCCCC(=O)OC1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)C(=O)C

Ordering Information

Biological Activity

Hydroxyprogesterone caproate is a synthetic progestational agent that functions as a progesterone receptor agonist. Upon binding and activating nuclear progesterone receptors, it modulates gene transcription involved in reproductive tissue regulation. This activation alters endometrial differentiation, inhibits ovulation, and increases cervical mucus viscosity to block sperm passage, thereby exerting potent progestational activity in cellular and physiological pathways. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 85 mg/mL (198.32 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 85 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.