CAS No. 80-49-9
| CAS Number | 80-49-9 | |
|---|---|---|
| Molecular Formula |
C17H24NO3.Br |
|
| Molecular Weight (MW) | 370.28 | |
| SMILES | C[N+]1(C2CCC1CC(C2)OC(=O)C(C3=CC=CC=C3)O)C.[Br-] |
Homatropine Methylbromide acts as a muscarinic acetylcholine receptor antagonist that targets muscarinic receptors in endothelial and smooth muscle tissues. By blocking endogenous acetylcholine binding, it inhibits downstream cholinergic receptor activation and intracellular calcium signaling pathways. This targeted receptor antagonism leads to functional phenotypes including smooth muscle relaxation, decreased gastrointestinal motility, and inhibition of vascular smooth muscle contraction. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
74 mg/mL
(199.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 74 mg/mL |
| Ethanol | 74 mg/mL |
| DMSO |
74 mg/mL
(199.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 74 mg/mL |
| Ethanol | 10 mg/mL |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
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- Homatropine Methylbromide Solubility in DMSO
- Homatropine Methylbromide Stock Solution
- Homatropine Methylbromide Storage
- Homatropine Methylbromide Stability
- Homatropine Methylbromide Molecular Weight
- Homatropine Methylbromide SMILES
- Homatropine Methylbromide Chemical Structure (2D and 3D)
- Homatropine Methylbromide SDS｜MSDS