CAS No. 51-45-6
Batch:
Purity:99.99
Chemical Structure
Check the
Histamine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 51-45-6 | |
|---|---|---|
| Molecular Formula |
C5H9N3 |
|
| Molecular Weight (MW) | 111.15 |
Histamine is an endogenous organic nitrogenous compound that acts as a potent agonist for histamine H1 and H2 receptors. It regulates local immune responses and gastrointestinal physiological functions while serving as a neurotransmitter in the central nervous system and peripheral tissues. Additionally, exogenous administration of histamine is widely utilized to induce experimental animal models of gastric and intestinal ulcers to investigate mucosal pathogenesis and screen ulcer therapeutics. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
22 mg/mL
(197.93 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 22 mg/mL |
| Ethanol | 22 mg/mL |
| DMSO |
22 mg/mL
(197.93 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
22 mg/mL
(197.93 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 7 mg/mL |
| Ethanol | 5 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.