Molecular Weight: 377.83 g/mol

HG-10-102-01 Chemical Structure
Chemical Structure
Check the HG-10-102-01 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 76 mg/mL (201.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 5 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name [4-[[5-chloro-4-(methylamino)pyrimidin-2-yl]amino]-3-methoxyphenyl]-morpholin-4-ylmethanone
CAS Number 1351758-81-0
Molecular Formula

C17H20ClN5O3

Molecular Weight (MW) 377.83
SMILES CNC1=NC(=NC=C1Cl)NC2=C(OC)C=C(C=C2)C(=O)N3CCOCC3
InChIKey YEVOZZZLKJKCCD-UHFFFAOYSA-N

Jump to

Note: Technical data last updated: Sep 1, 2026.