CAS No. 1443138-53-1
Batch:
Purity:99.88
Chemical Structure
Check the
GSK2200150A
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1'-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)spiro[6,7-dihydrothieno[3,2-c]pyran-4,4'-piperidine] | |
|---|---|---|
| CAS Number | 1443138-53-1 | |
| Molecular Formula |
C20H23NO3S |
|
| Molecular Weight (MW) | 357.47 | |
| SMILES | C1COC2(CCN(CC2)CC3=CC4=C(C=C3)OCCO4)C5=C1SC=C5 | |
| InChIKey | NCRPMBWORFWNGT-UHFFFAOYSA-N |
GSK2200150A is a small-molecule anti-tuberculosis agent identified through a high-throughput screening campaign, demonstrating potent activity against Mycobacterium tuberculosis with a minimum inhibitory concentration (MIC) of. By targeting whole-cell bacterial processes, it disrupts essential mycobacterial growth and viability. Consequently, this compound serves as a valuable tool for anti-tubercular research and development of novel therapeutic strategies. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
71 mg/mL
(198.61 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 18 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.