Molecular Weight: 985.13 g/mol
Chemical Structure
Check the
GSK215
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(101.5 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Chemical Information
| IUPAC Name | (2S,4R)-4-hydroxy-1-[(2S)-2-[[2-[4-[3-methoxy-4-[[4-[2-(methylcarbamoyl)anilino]-5-(trifluoromethyl)-2-pyridinyl]amino]phenyl]piperazin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide | |
|---|---|---|
| CAS Number | 2743427-26-9 | |
| Molecular Formula |
C50H59F3N10O6S |
|
| Molecular Weight (MW) | 985.13 | |
| SMILES | CNC(=O)C1=C(NC2=CC(=NC=C2C(F)(F)F)NC3=C(OC)C=C(C=C3)N4CCN(CC4)CC(=O)NC(C(=O)N5CC(O)CC5C(=O)NC(C)C6=CC=C(C=C6)C7=C(C)N=CS7)C(C)(C)C)C=CC=C1 | |
| InChIKey | ZGSWGXNEXAXEGV-XFCHVEHOSA-N |
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Note: Technical data last updated: Sep 1, 2026.