GSK215 Chemical Structure (2D and 3D)

2D Structure

2D chemical structural formula diagram.

3D Structure

This 3D model represents a theoretically simulated conformation and is for reference only.

Check the GSK215 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name	(2S,4R)-4-hydroxy-1-[(2S)-2-[[2-[4-[3-methoxy-4-[[4-[2-(methylcarbamoyl)anilino]-5-(trifluoromethyl)-2-pyridinyl]amino]phenyl]piperazin-1-yl]acetyl]amino]-3,3-dimethylbutanoyl]-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide
CAS Number	2743427-26-9
Molecular Formula	C₅₀H₅₉F₃N₁₀O₆S
Molecular Weight (MW)	985.13
SMILES	CNC(=O)C1=C(NC2=CC(=NC=C2C(F)(F)F)NC3=C(OC)C=C(C=C3)N4CCN(CC4)CC(=O)NC(C(=O)N5CC(O)CC5C(=O)NC(C)C6=CC=C(C=C6)C7=C(C)N=CS7)C(C)(C)C)C=CC=C1
InChIKey	ZGSWGXNEXAXEGV-XFCHVEHOSA-N

Concentration Volume Mass

Batch:

All in vitro solubility values are batch-tested experimental data (non-literature values).

Solvent	Solubility & Note
DMSO	100 mg/mL (101.5 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)

FAQ

Q: Why does a DMSO stock precipitate in media/saline?

A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.

How to fix it?