Molecular Weight: 380.4 g/mol

GRK5-IN-2 Chemical Structure
Chemical Structure
Check the GRK5-IN-2 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 76 mg/mL (199.78 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 2 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name 2-(furan-2-yl)-1-methyl-N-(3,4,5-trimethoxyphenyl)imidazo[4,5-c]pyridin-6-amine
CAS Number 1642839-27-7
Molecular Formula

C20H20N4O4
Molecular Weight (MW) 380.4
SMILES COC1=C(OC)C(=CC(=C1)NC2=NC=C3N=C([N](C)C3=C2)C4=CC=CO4)OC
InChIKey CRUXKUKVTMZKSO-UHFFFAOYSA-N

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Note: Technical data last updated: Sep 1, 2026.