CAS No. 596-51-0
Batch:
Purity:99.91
Chemical Structure
Check the
Glycopyrrolate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 596-51-0 | |
|---|---|---|
| Molecular Formula |
C19H28NO3.Br |
|
| Molecular Weight (MW) | 398.33 | |
| SMILES | C[N+]1(CCC(C1)OC(=O)C(C2CCCC2)(C3=CC=CC=C3)O)C.[Br-] |
Glycopyrrolate is a potent muscarinic acetylcholine receptor (mAChR) antagonist that targets M1, M2, and M3 receptor subtypes. By competitively blocking acetylcholine binding to muscarinic receptors, it inhibits cholinergic signaling pathways and downregulates intracellular calcium mobilization. This antagonism attenuates smooth muscle contraction and reduces glandular secretions in respiratory and gastrointestinal tissues.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 79 mg/mL |
| DMSO |
65 mg/mL
(163.18 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 59 mg/mL |
| DMSO |
80 mg/mL
(200.83 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 80 mg/mL |
| Ethanol | 26 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.