CAS No. 640-79-9
Batch:
Purity:99.35
Chemical Structure
Check the
Glycochenodeoxycholic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 640-79-9 | |
|---|---|---|
| Molecular Formula |
C26H43NO5 |
|
| Molecular Weight (MW) | 449.62 | |
| SMILES | CC(CCC(=O)NCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C |
Glycochenodeoxycholic acid is a glycine-conjugated primary bile acid that functions as an endogenous lipid detergent and signaling molecule. It modulates hepatic lipid metabolism and activates farnesoid X receptor signaling pathways. In hepatocyte models, elevated levels of glycochenodeoxycholic acid induce cell damage, promoting mitochondrial dysfunction, endoplasmic reticulum stress, and caspase-dependent apoptotic pathways.
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
90 mg/mL
(200.16 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 90 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Glycochenodeoxycholic acid Solubility in DMSO
- Glycochenodeoxycholic acid Stock Solution
- Glycochenodeoxycholic acid Storage
- Glycochenodeoxycholic acid Stability
- Glycochenodeoxycholic acid Molecular Weight
- Glycochenodeoxycholic acid SMILES
- Glycochenodeoxycholic acid Chemical Structure (2D and 3D)
- Glycochenodeoxycholic acid SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.