CAS No. 29031-19-4
Batch:
Purity:98
Chemical Structure
Check the
Glucosamine sulfate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 29031-19-4 | |
|---|---|---|
| Molecular Formula |
C6H13NO5.H2SO4 |
|
| Molecular Weight (MW) | 277.25 | |
| SMILES | C(C(C(C(C(C=O)N)O)O)O)O.OS(=O)(=O)O |
Glucosamine sulfate is an amino sugar precursor in glycosaminoglycan synthesis that modulates inflammatory responses in cartilage tissue. It attenuates interleukin-1beta-induced activation of the NF-kB pathway in chondrocytes, leading to reduced expression of pro-inflammatory mediators including cyclooxygenase-2. By suppressing extracellular matrix breakdown and inflammatory signalling, glucosamine sulfate helps preserve joint structure and chondrocyte function in models of osteoarthritis. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 55 mg/mL |
| DMSO |
4 mg/mL
(14.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Glucosamine sulfate Clinical Trials
- Glucosamine sulfate Solubility in DMSO
- Glucosamine sulfate Stock Solution
- Glucosamine sulfate Storage
- Glucosamine sulfate Stability
- Glucosamine sulfate Molecular Weight
- Glucosamine sulfate SMILES
- Glucosamine sulfate Chemical Structure (2D and 3D)
- Glucosamine sulfate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.