CAS No. 66-84-2
Batch:
Purity:98.4
Chemical Structure
Check the
Glucosamine hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 66-84-2 | |
|---|---|---|
| Molecular Formula |
C6H13NO5.HCl |
|
| Molecular Weight (MW) | 215.63 | |
| SMILES | C(C1C(C(C(C(O1)O)N)O)O)O.Cl |
Glucosamine hydrochloride is a naturally occurring amino sugar constituent of glycosaminoglycans that functions as an anti-inflammatory agent. It inhibits interleukin-1β-induced activation of the NF-kB pathway in human articular chondrocytes, downstream suppressing the expression of pro-inflammatory mediators and extracellular matrix-degrading enzymes. Consequently, it promotes glycosaminoglycan synthesis and helps preserve cartilage matrix integrity. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 43 mg/mL |
| DMSO |
4 mg/mL
(18.55 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Glucosamine hydrochloride Solubility in DMSO
- Glucosamine hydrochloride Stock Solution
- Glucosamine hydrochloride Storage
- Glucosamine hydrochloride Stability
- Glucosamine hydrochloride Molecular Weight
- Glucosamine hydrochloride SMILES
- Glucosamine hydrochloride Chemical Structure (2D and 3D)
- Glucosamine hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.