Molecular Weight: 453.44 g/mol

GLPG3312 Chemical Structure
Chemical Structure
Check the GLPG3312 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 91 mg/mL (200.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

IUPAC Name N-cyclopropyl-2-(difluoromethoxy)-6-methoxy-4-[5-(1-methylpyrazol-4-yl)benzimidazol-1-yl]benzamide
CAS Number 2340388-72-7
Molecular Formula

C23H21F2N5O3
Molecular Weight (MW) 453.44
InChIKey PFTXFNSHFZLJNT-UHFFFAOYSA-N

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Note: Technical data last updated: Sep 1, 2026.