Synonyms: GPVI, Glycoprotein VI
Glenzocimab (Anti-GP6 / Glycoprotein-6) is a Fab fragment of humanized anti-GPVI monoclonal antibody. Glenzocimab inhibits collagen-induced platelet aggregation. Glenzocimab has the potential for the research of acute ischemic stroke. MW: 145.5 KD.
| Featured Inhibitors | Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933 |
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| Description |
Glenzocimab (Anti-GP6 / Glycoprotein-6) is a Fab fragment of humanized anti-GPVI monoclonal antibody. Glenzocimab inhibits collagen-induced platelet aggregation. Glenzocimab has the potential for the research of acute ischemic stroke. MW: 145.5 KD.
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| CAS No. | 2101829-58-5 |
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| Molecular Weight | 145.5 kDa |
| Isotype | Human IgG1 |
| Source | CHO |
| Purification | AKTA |
| Sterility | 0.2 μM filtered |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
| NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|---|
| NCT06437431 | NOT_YET_RECRUITING | Drug: glenzocimab|Drug: placebo | Acute Ischemic Stroke | Fondation Ophtalmologique Adolphe de Rothschild | 2026-09 | PHASE2; PHASE3 |
| NCT05559398 | COMPLETED | Drug: Glenzocimab|Drug: Placebo | Stroke, Acute; Stroke, Ischemic | Assistance Publique - Hôpitaux de Paris | 2023-01-03 | PHASE2; PHASE3 |
| NCT05070260 | COMPLETED | Drug: Intravenous glenzocimab (ACT017) 1000 mg|Drug: Intrave | Acute Ischemic Stroke | Acticor Biotech | 2021-09-23 | PHASE2; PHASE3 |
| NCT04659109 | COMPLETED | Drug: glenzocimab|Drug: Placebo | SARS-CoV Infection; Acute Respiratory Distress Syndrome; COVID-19; ARDS | Acticor Biotech | 2020-12-16 | PHASE2 |
(data from https://clinicaltrials.gov, updated on 2025-06-25)
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