CAS No. 22427-39-0
Batch:
Purity:98.01
Chemical Structure
Check the
Ginsenoside Rg1
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 22427-39-0 | |
|---|---|---|
| Molecular Formula |
C42H72O14 |
|
| Molecular Weight (MW) | 801.01 | |
| SMILES | CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CC(C4C3(CCC(C4(C)C)O)C)OC5C(C(C(C(O5)CO)O)O)O)C)O)C)OC6C(C(C(C(O6)CO)O)O)O)C |
Ginsenoside Rg1 is a natural protopanaxatriol-type saponin that exhibits neuroprotective and anti-tumor activities. It reduces cerebral amyloid-beta (Aβ) accumulation and inhibits NF-κB nuclear translocation, thereby modulating inflammatory downstream functions and cellular stress pathways. These biological effects lead to suppressed neuroinflammation, attenuated neuronal apoptosis, and reduced cell proliferation across multiple disease models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(124.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(124.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.