CAS No. 1405-41-0

Batch: Purity:99.77
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Gentamicin Sulfate Chemical Structure
Chemical Structure
Check the Gentamicin Sulfate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1405-41-0
Molecular Formula

H2SO4.xUnspecified
SMILES CCN.CNC(C)C.CNC1C(O)C(OCC1(C)O)OC2C(N)CC(N)C(OC3OC(CCC3N)[R])C2O.CC(C)N.O[S](O)(=O)=O

Ordering Information

Biological Activity

Gentamicin Sulfate is a broad-spectrum aminoglycoside antibiotic that targets bacterial protein synthesis. It binds to the 30S ribosomal subunit, inducing codon misreading and disruption of translation in sensitive microorganisms. Beyond its antibacterial activity, gentamicin sulfate is widely utilized in biomedical research to establish experimental animal models of nephrotoxicity and acute renal failure. [1]

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 100 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.