Fulvestrant (ICI-182780): Mechanism of Action

Fulvestrant (ICI-182780) MOA:Targeting ER/PI3K-AKT-mTOR Pathway for Targeted Therapy Combinations

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Fulvestrant is a potent ER antagonist. It affects ER signaling pathways, by degrading ER, thereby inhibiting tumor growth.

Primary Applications and Mechanism of Action