CAS No. 59-30-3
Batch:
Purity:99.93
Chemical Structure
Check the
Folic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 59-30-3 | |
|---|---|---|
| Molecular Formula |
C19H19N7O6 |
|
| Molecular Weight (MW) | 441.40 | |
| SMILES | C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N |
Folic acid, an essential B-complex vitamin, acts as a fundamental cofactor in one-carbon transfer reactions crucial for nucleotide biosynthesis and amino acid metabolism. It serves as a precursor for tetrahydrofolate, supporting de novo purine and thymidylate synthesis, which drives DNA replication, repair, and cellular proliferation. Disruption of folate availability impairs genomic stability and suppresses cell growth. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
2 mg/mL
(4.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
44 mg/mL
(99.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.