Numerous clinical trials evaluate fludarabine phosphate across hematologic malignancies—including chronic lymphocytic leukemia, relapsed or refractory diffuse large B-cell lymphoma, and hematopoietic system cancers—spanning Phase I through Phase IV studies and observational registries. Sponsored by academic medical centers such as the University of California, San Diego, and biopharmaceutical entities including 3D Medicines and Kite, a Gilead Company, these protocols feature varied recruitment statuses ranging from recruiting and active to completed and terminated.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07055477 | RECRUITING | Relapsed and/or Refractory Mature T Cell Malignancy; Peripheral T-Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Hepatosplenic T-cell Lymphoma; Monomorphic Epithelialtropic Intestinal Lymphoma; Enteropathy Associated T-cell Lymphoma; Cutaneous T-Cell Lymphoma; Mycosis Fungoides; Subacute Panniculitis-like T-cell Lymphoma |
National Cancer Institute (NCI) |
2025-09-29 | PHASE1 |
| NCT06191887 | RECRUITING | B-Cell Non-Hodgkin Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Small Lymphocytic Lymphoma; Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Diffuse Large B-Cell Lymphoma; Refractory Follicular Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Marginal Zone Lymphoma; Refractory Small Lymphocytic Lymphoma; Refractory Transformed Chronic Lymphocytic Leukemia |
Mayo Clinic |
2024-03-18 | PHASE1 |
| NCT04877613 | ACTIVE_NOT_RECRUITING | Metastatic Medullary Thyroid Cancer; Recurrent Thyroid Gland Medullary Carcinoma |
University of Pennsylvania |
2021-08-19 | PHASE1 |
| NCT03935893 | ACTIVE_NOT_RECRUITING | Gastric Cancer; Colorectal Cancer; Pancreatic Cancer; Sarcoma; Mesothelioma; Neuroendocrine Tumors; Squamous Cell Cancer; Merkel Cell Carcinoma; Mismatch Repair Deficiency; Microsatellite Instability |
Udai Kammula |
2019-12-03 | PHASE2 |
| NCT06885697 | RECRUITING | Mesothelioma; Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Ovarian Neoplasms; Lung Neoplasms; Thymus Neoplasms; Colonic Neoplasms |
National Cancer Institute (NCI) |
2025-07-08 | PHASE1 |
| NCT05617625 | SUSPENDED | Myelodysplastic Syndromes; Graft Vs Host Disease; Graft-versus-host-disease |
Guenther Koehne |
2026-06 | PHASE2 |
| NCT05257083 | ACTIVE_NOT_RECRUITING | Multiple Myeloma |
Stichting European Myeloma Network |
2023-10-10 | PHASE3 |
| NCT05508009 | RECRUITING | SIOD; Cystinosis; FSGS; SLE Nephritis; CKD Stage 4 |
Alice Bertaina |
2023-01-10 | PHASE1; PHASE2 |
| NCT07759102 | NOT_YET_RECRUITING | Recurrent Multiple Myeloma; Refractory Multiple Myeloma |
University of California, Davis |
2026-09-01 | PHASE1 |
| NCT06205290 | WITHDRAWN | Leukemia, Lymphocytic, Chronic, B-Cell |
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company |
2024-01-16 | PHASE3 |
| NCT07164469 | NOT_YET_RECRUITING | Large B-cell Lymphoma; Hodgkin Lymphoma |
M.D. Anderson Cancer Center |
2026-12-28 | PHASE2 |
| NCT07479797 | RECRUITING | Relapsed or Refractory Large B-cell Lymphoma |
Kite, A Gilead Company |
2026-05-22 | PHASE3 |
| NCT05605899 | ACTIVE_NOT_RECRUITING | High-risk Large B-cell Lymphoma (LBCL) |
Kite, A Gilead Company |
2023-02-10 | PHASE3 |
| NCT07162038 | RECRUITING | Hematologic Malignancies; Hematologic Neoplasms |
National Cancer Institute (NCI) |
2025-11-14 | PHASE1 |
| NCT07803653 | NOT_YET_RECRUITING | Metastatic Castration-Resistant Prostate Adenocarcinoma; Stage IVB Prostate Cancer AJCC v8 |
Fred Hutchinson Cancer Center |
2026-10-31 | PHASE1 |
| NCT07228624 | RECRUITING | Myelodysplastic/Myeloproliferative Neoplasm; Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2026-02-04 | PHASE2 |
| NCT05092451 | RECRUITING | B-Cell Lymphoma; Myelodysplastic Syndromes (MDS); Acute Myeloid Leukemia (AML); Multiple Myeloma; Plasma Cell Leukemia; Hodgkin Lymphoma; T-cell Non-Hodgkin's Lymphoma/ T-cell Acute Lymphoblastic Leukmeia; Myelodysplastic Syndrome / Chronic Myelomonocytic Leukemia; Blastic Transformation of Chronic Myeloid Leukemia; Germ Cell Tumors |
M.D. Anderson Cancer Center |
2022-11-01 | PHASE1; PHASE2 |
| NCT06153251 | RECRUITING | Relapsed and/or Refractory Multiple Myeloma |
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company |
2024-01-23 | PHASE1 |
| NCT07493538 | RECRUITING | AML; MDS; Acute Leukemia; Acute Myeloid Leukemia; Myelodysplastic Syndromes |
Masonic Cancer Center, University of Minnesota |
2026-04-10 | PHASE2 |
| NCT06879340 | RECRUITING | B-Cell Non-Hodgkin Lymphoma; B-cell Acute Lymphoblastic Leukemia |
University of Kansas Medical Center |
2025-03-31 | PHASE1 |
| NCT07396480 | RECRUITING | Venentoclax; Myeloid Malignancies; Conditioning; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; Acute Myeloid Leucemia; Myeldysplastic Syndrome (MDS) |
First Affiliated Hospital of Zhejiang University |
2026-03-01 | PHASE3 |
| NCT07509034 | NOT_YET_RECRUITING | Extensive-Stage Small Cell Lung Cancer; Extrapulmonary Neuroendocrine Carcinoma; Recurrent or Refractory; Solid Tumors |
National Cancer Institute (NCI) |
2026-09-09 | PHASE1 |
| NCT05477589 | RECRUITING | Acute Myeloid Leukemia (AML) in Remission; Stem Cell Transplantation |
Vastra Gotaland Region |
2022-06-07 | PHASE3 |
| NCT07569965 | NOT_YET_RECRUITING | Mantle Cell Lymphoma (MCL) |
Miltenyi Biomedicine GmbH |
2026-09 | PHASE2 |
| NCT06364423 | RECRUITING | Leukemia, Lymphocytic, Chronic, B-Cell; B-Lymphocytic Leukemia, Chronic; B-Cell Chronic Lymphocytic Leukemia; Acute Lymphoblastic Leukemia; Lymphoblastic Lymphoma; Leukemia, Acute Lymphoblastic; Small Lymphocytic Lymphoma |
National Cancer Institute (NCI) |
2024-09-03 | PHASE1; PHASE2 |
| NCT06961357 | RECRUITING | Melanoma |
H. Lee Moffitt Cancer Center and Research Institute |
2025-12-03 | PHASE1; PHASE2 |
| NCT03121001 | RECRUITING | Sickle Cell Disease |
University of Illinois at Chicago |
2017-03-20 | PHASE2 |
| NCT07582172 | RECRUITING | Acute Myeloid Leukemia With Complex Karyotype; Myelodysplastic Chronic Myelomonocytic Leukemia; Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Myelodysplastic Chronic Myelomonocytic Leukemia; Recurrent Myelodysplastic Syndrome; Recurrent Secondary Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia; Refractory Myelodysplastic Chronic Myelomonocytic Leukemia; Refractory Myelodysplastic Syndrome; Refractory Secondary Acute Myeloid Leukemia |
City of Hope Medical Center |
2027-04-05 | PHASE2 |
| NCT07227571 | RECRUITING | Advanced Osteosarcoma; Recurrent Osteosarcoma; Refractory Osteosarcoma |
Fred Hutchinson Cancer Center |
2026-01-16 | PHASE1 |
| NCT07764978 | RECRUITING | Newly Diagnosed Multiple Myeloma |
AstraZeneca |
2026-06-26 | PHASE3 |
| NCT07410676 | RECRUITING | Cancer; Sarcoma; Leukaemia; Breast Cancer (Locally Advanced or Metastatic); Lung Cancer (Diagnosis); Colorectal Cancer; Melanoma (Skin Cancer); Bladder Cancer; Kidney Cancer; Pancreatic Cancer Metastatic; Liver Cancer (Primary and Metastatic); Ovarian Cancer; Esophageal Cancer; Glioblastoma; Non-Melanoma Skin Cancer |
Essen Biotech |
2026-02-01 | PHASE1; PHASE2 |
| NCT07613723 | RECRUITING | Ovarian Cancer; Squamous Non-Small Cell Lung Cancer (NSCLC); Synovial Sarcomas; Head and Neck Cancer |
Zelluna Immunotherapy AS |
2026-05-11 | PHASE1 |
| NCT07614061 | RECRUITING | Biliary Tract Neoplasms; Cholangiocarcinoma, Intrahepatic; Cholangiocarcinoma, Extrahepatic; Cholangiocarcinoma, Perihilar; Gallbladder Cancer |
Shanghai Zhongshan Hospital |
2026-05 | PHASE1 |
| NCT06815003 | RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Chronic Myelomonocytic Leukemia; Graft Versus Host Disease; Myelodysplastic Syndrome; Myeloproliferative Neoplasm |
City of Hope Medical Center |
2025-04-18 | PHASE2 |
| NCT07223021 | RECRUITING | B-cell Acute Lymphoblastic Leukemia |
Memorial Sloan Kettering Cancer Center |
2025-10-20 | PHASE3 |
| NCT06680752 | RECRUITING | Acute Myeloid Leukemia, in Relapse; Acute Myeloid Leukemia Refractory; MDS (Myelodysplastic Syndrome) |
ARCE Therapeutics, Inc. |
2025-05-20 | PHASE1; PHASE2 |
| NCT05114837 | WITHDRAWN | Lymphoma Leukemia |
Masonic Cancer Center, University of Minnesota |
2024-09 | PHASE1; PHASE2 |
| NCT04196413 | RECRUITING | Glioma of Spinal Cord; Glioma of Brainstem |
Stanford University |
2020-06-04 | PHASE1 |
| NCT07758673 | NOT_YET_RECRUITING | Recurrent B Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory B Lymphoblastic Lymphoma |
City of Hope Medical Center |
2027-04-17 | PHASE1 |
| NCT07668557 | RECRUITING | Acute Myeloid Leukemia (AML) |
iCell Gene Therapeutics |
2026-06-10 | PHASE1 |
| NCT05665062 | ACTIVE_NOT_RECRUITING | CLL/SLL; NHL; Mantle Cell Lymphoma; Follicular Lymphoma; Large B-cell Lymphoma; Indolent B-Cell Non-Hodgkin Lymphoma; Diffuse Large B Cell Lymphoma |
Synthekine |
2023-04-23 | PHASE1 |
| NCT02621021 | RECRUITING | Melanoma |
National Cancer Institute (NCI) |
2015-12-04 | PHASE2 |
| NCT06262438 | RECRUITING | Acute Myeloid Leukemia in Children |
Princess Maxima Center for Pediatric Oncology |
2024-02-06 | PHASE2 |
| NCT06968195 | SUSPENDED | Advanced Hepatocellular Carcinoma; Metastatic Hepatocellular Carcinoma; Recurrent Hepatocellular Carcinoma; Refractory Hepatocellular Carcinoma; Stage III Hepatocellular Carcinoma AJCC v8; Stage IV Hepatocellular Carcinoma AJCC v8 |
Roswell Park Cancer Institute |
2026-07-15 | PHASE1 |
| NCT07340853 | SUSPENDED | Multiple Myeloma; Recurrent Multiple Myeloma; Refractory Multiple Myeloma |
Thomas Martin, MD |
2026-02-28 | PHASE1 |
| NCT05625594 | RECRUITING | Central Nervous System Lymphoma |
City of Hope Medical Center |
2023-06-29 | PHASE1 |
| NCT07015983 | ACTIVE_NOT_RECRUITING | Lupus Erythematosus, Systemic; Lupus Nephritis |
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company |
2025-07-14 | PHASE2 |
| NCT07085156 | NOT_YET_RECRUITING | MDS |
Ruijin Hospital |
2025-08-01 | PHASE2 |
| NCT05088356 | ACTIVE_NOT_RECRUITING | Allogeneic Hematopoietic Cell Transplantation (HCT); Advanced Hematologic Malignancies; Acute Leukemia; Chronic Myelogenous Leukemia; Myelodysplastic Syndromes; Myeloproliferative Disorders |
Stanford University |
2021-09-07 | PHASE1 |
| NCT07342738 | NOT_YET_RECRUITING | KRAS G12V; KRAS G12D; Solid Tumor |
Sun Yat-sen University |
2026-02-01 | EARLY_PHASE1 |
| NCT03670966 | RECRUITING | Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Acute Myeloid Leukemia in Remission; Chronic Myelomonocytic Leukemia; Myelodysplastic Syndrome With Excess Blasts; Recurrent Acute Lymphoblastic Leukemia; Recurrent Acute Myeloid Leukemia; Refractory Acute Lymphoblastic Leukemia; Refractory Acute Myeloid Leukemia; Recurrent Mixed Phenotype Acute Leukemia; Refractory Mixed Phenotype Acute Leukemia; Hematopoietic and Lymphoid Cell Neoplasm |
Fred Hutchinson Cancer Center |
2019-07-10 | PHASE1; PHASE2 |
| NCT07015242 | RECRUITING | Lymphoma |
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company |
2025-11-06 | PHASE2 |
| NCT07078721 | NOT_YET_RECRUITING | Aplastic Anemia Idiopathic |
Institute of Hematology & Blood Diseases Hospital, China |
2025-07-20 | PHASE2 |
| NCT06825455 | NOT_YET_RECRUITING | Advanced Solid Tumors; Ovarian Cancers; Peritoneal (metastatic) Cancer |
Peking University |
2025-03-01 | EARLY_PHASE1 |
| NCT06720324 | RECRUITING | Hematologic Malignancy |
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
2024-12-31 | PHASE1; PHASE2 |
| NCT04232085 | RECRUITING | Primary Immune Deficiency Disorder; Immune Deficiency Disease; Bone Marrow Failure; Short Telomere Length; Fanconi Anemia; Non Fanconi DNA-DSB Repair Disorder; Hoyeraal-Hreidarsson Syndrome; Dyskeratosis Congenita; Telomere Biology Disorder; Short Telomere Syndrome |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2020-02-12 | PHASE2 |
| NCT07101432 | RECRUITING | Head and Neck Cancer |
M.D. Anderson Cancer Center |
2025-12-19 | PHASE1 |
| NCT07131085 | NOT_YET_RECRUITING | MDS; AML |
Anhui Provincial Hospital |
2025-08-15 | PHASE1 |
| NCT07441967 | NOT_YET_RECRUITING | Hematologic Malignancies |
Institute of Hematology & Blood Diseases Hospital, China |
2026-02-20 | PHASE2 |
| NCT03622788 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Aplastic Anemia; Bone Marrow Failure; Chronic Lymphocytic Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Follicular Lymphoma; Hodgkin Lymphoma; Mantle Cell Lymphoma; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Non-Hodgkin Lymphoma; Plasma Cell Myeloma |
M.D. Anderson Cancer Center |
2019-08-08 | PHASE1; PHASE2 |
| NCT06500273 | RECRUITING | Large B-cell Lymphoma |
Allogene Therapeutics |
2024-06-18 | PHASE2 |
| NCT03500731 | RECRUITING | Idiopathic Pulmonary Fibrosis; Emphysema or COPD |
Paul Szabolcs |
2018-04-19 | PHASE1; PHASE2 |
| NCT02928991 | ACTIVE_NOT_RECRUITING | Bone Marrow Failure Syndromes |
Children's Hospital of Philadelphia |
2015-04 | EARLY_PHASE1 |
| NCT05735717 | RECRUITING | Hematologic Malignancy; Acute Leukemia; Remission; Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia; AML; TP53; Intrachromosomal Amplification of Chromosome 21; Cytogenetic Abnormality; CNS Leukemia; Minimal Residual Disease; Myelodysplasia; Juvenile Myelomonocytic Leukemia; Somatic Mutation; PTPN11 Gene Mutation; N-RAS Gene Amplification; Neurofibromatosis 1; NF1 Mutation; CBL Gene Mutation; Monosomy 7; Chromosome Abnormality; Fetal Hemoglobin; Lymphoblastic Lymphoma; High Grade Non-Hodgkin's Lymphoma, Adult |
Masonic Cancer Center, University of Minnesota |
2023-05-11 | PHASE2 |
| NCT06641453 | NOT_YET_RECRUITING | Hepatocellular Carcinoma (HCC) |
Chinese PLA General Hospital |
2024-11-15 | PHASE1; PHASE2 |
| NCT04643574 | ACTIVE_NOT_RECRUITING | Solid Tumor, Adult |
Centre Hospitalier Universitaire Vaudois |
2021-03-09 | PHASE1 |
| NCT02133196 | RECRUITING | Advanced Non-Small Cell Lung Cancer; Squamous Cell Carcinoma; Advanced NSCLC; Adenosquamous Carcinoma; Adenocarcinoma |
National Cancer Institute (NCI) |
2014-10-23 | PHASE2 |
| NCT05805605 | RECRUITING | Acute Myelogenous Leukemia; Acute Lymphocytic Leukemia; Biphenotypic Acute Leukemia; Undifferentiated Leukemia; Prolymphocytic Leukemia; Chronic Myelogenous Leukemia; Plasma Cell Leukemia; Myelodysplastic Syndromes; Leukemia, Myeloid; Myelodysplastic Syndrome With Excess Blasts-1; Burkitt Lymphoma; Relapsed T-Cell Lymphoma; Relapsed Chronic Lymphocytic Leukemia; Small Lymphocytic Lymphoma; Marginal Zone Lymphoma; Follicular Lymphoma; Myeloproliferative Neoplasm; Myelofibrosis |
Masonic Cancer Center, University of Minnesota |
2023-05-01 | PHASE2 |
| NCT06609928 | RECRUITING | Recurrent Childhood Acute Myeloid Leukemia; Refractory Childhood Acute Myeloid Leukemia |
Fred Hutchinson Cancer Center |
2025-02-24 | PHASE1 |
| NCT03214562 | RECRUITING | High Risk Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2017-09-26 | PHASE1; PHASE2 |
| NCT06613035 | NOT_YET_RECRUITING | Acute Myeloid Leukemia |
Institute of Hematology & Blood Diseases Hospital, China |
2024-09-30 | PHASE3 |
| NCT04007029 | ACTIVE_NOT_RECRUITING | CD19 Positive; CD20 Positive; Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Diffuse Large B-Cell Lymphoma; Refractory Follicular Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Refractory Small Lymphocytic Lymphoma |
Jonsson Comprehensive Cancer Center |
2019-10-04 | PHASE1 |
| NCT07087002 | RECRUITING | Medulloblastoma; Central Nervous System Embryonal Tumor; Refractory Medulloblastoma; Recurrent Medulloblastoma; Pediatric Brain Tumor; Embryonal Tumor With Multilayered Rosettes (ETMR); Pineoblastoma; Atypical Teratoid/Rhabdoid Tumor (ATRT) of the CNS; CNS Neuroblastoma; FOXR2-activated |
Stanford University |
2025-08-28 | PHASE1 |
| NCT06265220 | ACTIVE_NOT_RECRUITING | Lupus Nephritis - WHO Class III; Lupus Nephritis - WHO Class IV; Refractory Systemic Lupus Erythematosus; SLE |
Artiva Biotherapeutics, Inc. |
2024-04-03 | PHASE1 |
| NCT04022239 | RECRUITING | Hematopoietic and Lymphoid System Neoplasm |
M.D. Anderson Cancer Center |
2020-03-13 | PHASE1; PHASE2 |
| NCT07024147 | NOT_YET_RECRUITING | B-Cell Non-Hodgkin Lymphoma; Large B Cell Diffuse Lymphoma; Follicular Lymphoma; Marginal Zone B Cell Lymphoma; Mantle Cell Lymphoma (MCL) |
Peking University Cancer Hospital & Institute |
2025-07-01 | PHASE1 |
| NCT04881240 | RECRUITING | Acute Lymphoblastic Leukemia, in Relapse; Acute Lymphoblastic Leukemia, Refractory; Pediatric ALL |
St. Jude Children's Research Hospital |
2024-02-14 | PHASE1 |
| NCT06253663 | ACTIVE_NOT_RECRUITING | Relapsed/Refractory Mantle Cell Lymphoma; Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia |
Kite, A Gilead Company |
2024-03-18 | PHASE2 |
| NCT03190941 | RECRUITING | Pancreatic Cancer; Gastric Cancer; Gastrointestinal Cancer; Colon Cancer; Rectal Cancer |
National Cancer Institute (NCI) |
2017-09-21 | PHASE1; PHASE2 |
| NCT07492628 | RECRUITING | Bladder Cancer; Urothelial Carcinoma; Metastatic Urothelial Carcinoma; Locally Advanced Urothelial Carcinoma; Upper Tract Urothelial Carcinoma |
Beijing Biotech |
2026-03-02 | PHASE1 |
| NCT07598955 | RECRUITING | B2 Thymoma; Thymic Carcinoma |
Beijing Biotech |
2026-03-02 | PHASE1; PHASE2 |
| NCT06939270 | NOT_YET_RECRUITING | Solid Tumor |
Chinese PLA General Hospital |
2025-05-01 | PHASE1; PHASE2 |
| NCT04370301 | RECRUITING | Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2021-02-09 | PHASE2 |
| NCT07551349 | RECRUITING | Advanced or Metastatic Clear Cell Renal Cell Carcinoma |
Beijing Biotech |
2026-02-02 | PHASE1; PHASE2 |
| NCT07551336 | RECRUITING | Malignant Glioma; High-Grade Gliomas; Glioblastoma; Recurrent High-Grade Gliomas; Recurrent Glioblastoma |
Beijing Biotech |
2026-03-02 | PHASE1 |
| NCT04859946 | ACTIVE_NOT_RECRUITING | Hematologic and Lymphocytic Disorder |
M.D. Anderson Cancer Center |
2022-01-11 | PHASE2 |
| NCT05678205 | WITHDRAWN | Breast Cancer; Gastric Cancer; Gastroesophageal Junction Adenocarcinoma |
Artiva Biotherapeutics, Inc. |
2023-08-01 | PHASE1; PHASE2 |
| NCT05201183 | WITHDRAWN | Acute Myeloid Leukemia; Chronic Myeloid Leukemia; Acute Lymphocytic Leukemia; Myelodysplastic Syndromes |
Naoyuki G. Saito, M.D., Ph.D. |
2023-10 | PHASE1; PHASE2 |
| NCT06557265 | RECRUITING | Lupus Nephritis; Primary Membranous Nephropathy |
Nkarta, Inc. |
2024-06-13 | PHASE1; PHASE2 |
| NCT06898385 | RECRUITING | Pancreatic Cancer |
Sun Yat-sen University |
2025-03-27 | PHASE1 |
| NCT03964506 | RECRUITING | Acute Myeloid Leukemia; Myelodysplastic Syndromes; Chronic Myelomonocytic Leukemia; Atypical Chronic Myeloid Leukemia; Chronic Monocytic Leukemia; Myelofibrosis; Myelodysplastic/Myeloproliferative Neoplasm |
Omar Aljitawi |
2020-07-01 | EARLY_PHASE1 |
| NCT06838832 | RECRUITING | Non-hodgkin Lymphoma,B Cell |
Chinese PLA General Hospital |
2025-07-27 | PHASE1; PHASE2 |
| NCT06204991 | RECRUITING | Melanoma Stage III; Melanoma Stage IV; Melanoma |
Inge Marie Svane |
2025-04-01 | PHASE1 |
| NCT04897321 | RECRUITING | Pediatric Solid Tumor; Osteosarcoma; Rhabdomyosarcoma; Neuroblastoma; Ewing Sarcoma; Wilms Tumor; Adrenocortical Cancer; Desmoplastic Small Round Cell Tumor; Germ Cell Cancer; Rhabdoid Tumor; Clear Cell Sarcoma; Hepatoblastoma; Melanoma; Carcinoma; Malignant Peripheral Nerve Sheath Tumors; Soft Tissue Sarcoma |
St. Jude Children's Research Hospital |
2022-07-06 | PHASE1 |
| NCT04375631 | RECRUITING | Recurrent Acute Myeloid Leukemia; Recurrent Chronic Myelomonocytic Leukemia; Recurrent Myelodysplastic Syndrome; Refractory Acute Myeloid Leukemia; Refractory Chronic Myelomonocytic Leukemia; Refractory Mixed Phenotype Acute Leukemia; Refractory Myelodysplastic Syndrome; Refractory Acute Leukemia of Ambiguous Lineage; Refractory Acute Undifferentiated Leukemia |
Fred Hutchinson Cancer Center |
2020-12-03 | PHASE1 |
| NCT04510051 | RECRUITING | Malignant Brain Neoplasm; Recurrent Malignant Brain Neoplasm; Refractory Malignant Brain Neoplasm |
City of Hope Medical Center |
2020-12-04 | PHASE1 |
| NCT07589530 | RECRUITING | Advanced Solid Tumors; Metastatic Solid Tumors; TROP2-Expressing Solid Tumors |
Beijing Biotech |
2026-03-02 | PHASE1; PHASE2 |
| NCT05736419 | RECRUITING | Sickle Cell Disease; Thalassemia, Beta; Thalassemia |
Memorial Sloan Kettering Cancer Center |
2023-02-09 | PHASE2 |
| NCT06152172 | ACTIVE_NOT_RECRUITING | Idiopathic Inflammatory Myopathies; Diffuse Cutaneous Systemic Sclerosis; SLE Nephritis; ANCA Associated Vasculitis |
David Porter |
2024-08-05 | PHASE1 |
| NCT05183035 | RECRUITING | Acute Myeloid Leukemia |
PedAL BCU, LLC |
2022-10-01 | PHASE3 |
| NCT07416682 | RECRUITING | High-risk Plasma Cell Neoplasms |
Affiliated Hospital to Academy of Military Medical Sciences |
2026-04-14 | EARLY_PHASE1 |
| NCT04540380 | ACTIVE_NOT_RECRUITING | Renal Failure |
Massachusetts General Hospital |
2021-09-01 | PHASE1 |
| NCT01804634 | RECRUITING | Refractory and/or Relapsed Metastatic Solid Tumors |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2013-03-27 | PHASE2 |
| NCT05400122 | SUSPENDED | Colorectal Cancer; Hematologic Malignancy; Rectum Cancer; Acute Myeloid Leukemia; Myelodysplastic Syndromes; Acute Lymphoblastic Leukemia; Chronic Myeloid Leukemia; Chronic Lymphocytic Leukemia; Hodgkin Lymphoma; Non Hodgkin Lymphoma; Myeloproliferative Syndrome; Plasma Cell Myeloma; Gastric Cancer; Esophageal Cancer; Esophagus Cancer; Gastric Cancer, Metastatic; Unresectable Esophageal Cancer; Metastatic Esophageal Cancer |
David Wald |
2022-09-09 | PHASE1 |
| NCT04792489 | RECRUITING | Refractory Diffuse Large B Cell Lymphoma (DLBCL); Relapsed Diffuse Large B Cell Lymphoma; High Grade B-cell Lymphoma (HGBCL); Primary Mediastinal B-cell Lymphoma (PMBCL); Transformed Lymphoma; Central Nervous System Lymphoma; Mantle Cell Lymphoma (MCL); Richter Transformation; Transplant-ineligible 2nd Line DLBCL |
Miltenyi Biomedicine GmbH |
2021-05-25 | PHASE2 |
| NCT06385808 | NOT_YET_RECRUITING | Relapse Leukemia; Refractory Acute Myeloid Leukemia; Conditioning; Hematopoietic Stem Cell Transplantation |
First Affiliated Hospital Xi'an Jiaotong University |
2024-05-01 | |
| NCT06098326 | ACTIVE_NOT_RECRUITING | Myelodysplastic Syndromes |
Asan Medical Center |
2018-03-06 | PHASE2 |
| NCT04024761 | RECRUITING | Acute Myeloid Leukemia; Myelodysplastic Syndromes; Myeloproliferative Neoplasm; Juvenile Myelomonocytic Leukemia |
Dana-Farber Cancer Institute |
2019-08-31 | PHASE1 |
| NCT02143830 | RECRUITING | Fanconi Anemia; Severe Marrow Failure; Myelodysplastic Syndrome (MDS); Acute Myelogenous Leukemia (AML) |
Children's Hospital Medical Center, Cincinnati |
2014-04 | PHASE2 |
| NCT06001788 | RECRUITING | AML; AML With Mutated NPM1; Hematologic Malignancy; KMT2Ar; NPM1 Mutation; MLL Rearrangement; Leukemia; Acute Myeloid Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Acute Leukemia; Neoplasms by Histologic Type |
Kura Oncology, Inc. |
2024-02-22 | PHASE1 |
| NCT06773091 | RECRUITING | Advanced Solid Tumors |
Shanghai NK Cell Technology Co., LTD |
2025-02-07 | PHASE1 |
| NCT02869217 | ACTIVE_NOT_RECRUITING | NY-ESO-1 Expressing Solid Tumors in HLA-A2 Positive Patients; Synovial Sarcoma; Melanoma; Esophageal Cancer; Ovarian Cancer; Lung Cancer; Bladder Cancer; Liver Cancer |
University Health Network, Toronto |
2016-09 | PHASE1 |
| NCT01962415 | RECRUITING | Primary Immunodeficiency (PID); Congenital Bone Marrow Failure Syndromes; Inherited Metabolic Disorders (IMD); Hereditary Anemias; Inflammatory Conditions; Systemic Juvenile Idiopathic Arthritis (sJIA); Juvenile Rheumatoid Arthritis (JRA) |
Paul Szabolcs |
2014-02-04 | PHASE2 |
| NCT06961786 | ACTIVE_NOT_RECRUITING | Metastatic Melanoma |
TILT Biotherapeutics Ltd. |
2025-06-25 | PHASE1 |
| NCT06809712 | RECRUITING | Hematologic Disease |
He Huang |
2022-08-04 | PHASE1 |
| NCT01176006 | ACTIVE_NOT_RECRUITING | DOCK8 Deficiency |
National Cancer Institute (NCI) |
2010-10-05 | PHASE2 |
| NCT07770802 | NOT_YET_RECRUITING | Clear Cell Renal Cell Carcinoma |
Qingdao Sino-Cell Biomedicine Co., Ltd. |
2026-10 | PHASE1 |
| NCT05521087 | WITHDRAWN | Acute Leukemias; Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia; Acute Leukemia of Ambiguous Lineage |
Janssen Research & Development, LLC |
2025-12-26 | PHASE1 |
| NCT05672173 | ACTIVE_NOT_RECRUITING | Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory Transformed Chronic Lymphocytic Leukemia; Richter Syndrome |
City of Hope Medical Center |
2023-06-02 | PHASE2 |
| NCT03494569 | SUSPENDED | Acute Lymphoblastic Leukemia; Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia; Acute Myeloid Leukemia in Remission; Hematopoietic Cell Transplantation Recipient; Minimal Residual Disease; Myelodysplastic Syndrome; Secondary Acute Myeloid Leukemia |
City of Hope Medical Center |
2018-07-06 | PHASE1 |
| NCT06096038 | RECRUITING | Head and Neck Cancer; Relapse; Recurrent; Refractory Cancer |
UNC Lineberger Comprehensive Cancer Center |
2024-04-05 | PHASE1 |
| NCT04855253 | SUSPENDED | DLBCL; Diffuse Large B Cell Lymphoma; High-grade B-cell Lymphoma; DLBCL Arising From Follicular Lymphoma |
Masonic Cancer Center, University of Minnesota |
2021-06-09 | PHASE1; PHASE2 |
| NCT04098393 | ACTIVE_NOT_RECRUITING | Hematologic Malignancies |
Memorial Sloan Kettering Cancer Center |
2019-09-18 | PHASE1 |
| NCT04904588 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Acute Myelogenous Leukemia; Mixed Phenotype Acute Leukemia; Acute Leukemia; Myelodysplastic Syndromes; Chronic Myelogenous Leukemia; Chronic Lymphocytic Leukemia; Lymphoma |
Center for International Blood and Marrow Transplant Research |
2021-09-30 | PHASE2 |
| NCT06756152 | RECRUITING | Biphenotypic Acute Leukemia; Acute Lymphoblastic Leukemia; Myeloblastic Leukemia; Bilinear Leukemia; Malignant Lymphoma, Non-Hodgkin; Myelodysplastic Syndrome |
Federal Research Institute of Pediatric Hematology, Oncology and Immunology |
2024-07-10 | PHASE2; PHASE3 |
| NCT05582590 | NOT_YET_RECRUITING | Oropharyngeal Cancer; Human Papilloma Virus; Head and Neck Cancer; Head and Neck Squamous Cell Carcinoma; Oropharyngeal Squamous Cell Carcinoma; Oropharyngeal Cancer, Metastatic; Head and Neck Cancer Metastatic; HPV-Related Squamous Cell Carcinoma; HPV-Related Mucosal Head and Neck Squamous Cell Carcinoma; Relapsed Oropharyngeal SCC; Refractory Oropharyngeal Squamous Cell Carcinoma |
NexImmune Inc. |
2025-03-31 | PHASE1 |
| NCT04217278 | ACTIVE_NOT_RECRUITING | Acute Myeloid Leukaemia; High-risk Myelodysplastic Syndrome |
University of Birmingham |
2020-01-27 | PHASE2; PHASE3 |
| NCT04384692 | ACTIVE_NOT_RECRUITING | Primary Myelofibrosis; Secondary Myelofibrosis |
Fred Hutchinson Cancer Center |
2020-12-18 | PHASE2 |
| NCT06342986 | ACTIVE_NOT_RECRUITING | Gynecologic Cancer; Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cavity Cancer |
Masonic Cancer Center, University of Minnesota |
2024-07-11 | PHASE1 |
| NCT04803058 | TERMINATED | Kidney Transplantation |
ITB-Med LLC |
2022-12-14 | PHASE2 |
| NCT05478837 | TERMINATED | Diffuse Midline Glioma, H3 K27M-Mutant |
University of California, San Francisco |
2023-07-20 | PHASE1 |
| NCT05040568 | COMPLETED | Colon Cancer; Resected Stage |
M.D. Anderson Cancer Center |
2022-02-28 | PHASE1 |
| NCT05513612 | WITHDRAWN | Acute Myeloid Leukemia (AML); B-cell Non-Hodgkin's Lymphoma (B-NHL); Multiple Myeloma (MM); T-Cell Leukemia/Lymphoma, Adult; B-cell Acute Lymphoblastic Leukemia (B-ALL) |
Shanghai Pudong Hospital |
2020-08-01 | PHASE1 |
| NCT06119685 | RECRUITING | NHL; Multiple Myeloma; Blood Cancer; Refractory Non-Hodgkin Lymphoma; Relapsed Non-Hodgkin Lymphoma; Refractory Multiple Myeloma; Relapsed Multiple Myeloma |
Indapta Therapeutics, INC. |
2023-10-25 | PHASE1; PHASE2 |
| NCT03602157 | ACTIVE_NOT_RECRUITING | Lymphoma; Immune System Diseases; Immunoproliferative Disorders; Lymphatic Diseases; Lymphoproliferative Disorders; Neoplasms; Cutaneous Lymphoma; Cutaneous Anaplastic Large Cell Lymphoma; Mycosis Fungoides; Sezary Syndrome; Lymphomatoid Papulosis; Cutaneous T Cell Lymphoma; Gray Zone Lymphoma |
UNC Lineberger Comprehensive Cancer Center |
2018-10-29 | PHASE1 |
| NCT06532799 | RECRUITING | Stomach Cancer; Stomach Cancer Recurrent; Stomach Cancer, Adenocarcinoma; Esophageal Cancer; Esophageal Cancer Metastatic to Bone; Esophageal Cancer Metastatic to Lung; Esophageal Cancer Metastatic to Liver |
Essen Biotech |
2024-09-10 | PHASE1; PHASE2 |
| NCT06532812 | RECRUITING | Breast Cancer; Breast Carcinoma; Breast Cancer Metastatic; Breast Cancer Triple Negative |
Essen Biotech |
2024-08-22 | PHASE1; PHASE2 |
| NCT06696833 | RECRUITING | B-Cell Acute Lymphoblastic Leukemia, Adult |
The First Affiliated Hospital of Soochow University |
2024-12-01 | EARLY_PHASE1 |
| NCT05577000 | ACTIVE_NOT_RECRUITING | Refractory Multiple Myeloma; Relapsed Multiple Myeloma |
Thomas Martin, MD |
2021-10-18 | PHASE1 |
| NCT07074496 | RECRUITING | Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia |
The First Affiliated Hospital of Soochow University |
2024-01-01 | EARLY_PHASE1 |
| NCT05566223 | WITHDRAWN | Carcinoma, Non-Small-Cell Lung; Metastatic Non Small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer; Squamous Cell Lung Cancer; Adenocarcinoma of Lung; Large Cell Lung Cancer |
Intima Bioscience, Inc. |
2023-02 | PHASE1; PHASE2 |
| NCT05991908 | RECRUITING | Acute Myeloid Leukemia; Myelodysplastic Syndromes |
Shanghai Jiao Tong University School of Medicine |
2023-10-19 | PHASE3 |
| NCT05907746 | ACTIVE_NOT_RECRUITING | GATA2; Immunodeficiency |
National Cancer Institute (NCI) |
2023-11-29 | PHASE2 |
| NCT04074746 | COMPLETED | Recurrent Anaplastic Large Cell Lymphoma; Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Classic Hodgkin Lymphoma; Recurrent Mycosis Fungoides; Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified; Refractory Anaplastic Large Cell Lymphoma; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Classic Hodgkin Lymphoma; Refractory Mycosis Fungoides; Refractory Peripheral T-Cell Lymphoma, Not Otherwise Specified |
M.D. Anderson Cancer Center |
2020-07-18 | PHASE1; PHASE2 |
| NCT06532643 | RECRUITING | Relapsed/Refractory Lymphoma |
Shanghai First Song Biotechnology Co., LTD |
2023-08-24 | EARLY_PHASE1 |
| NCT03696784 | ACTIVE_NOT_RECRUITING | Lymphoma; Lymphoma, B-Cell; Immune System Diseases; Immunoproliferative Disorders; Lymphatic Diseases |
UNC Lineberger Comprehensive Cancer Center |
2019-03-12 | PHASE1 |
| NCT03455504 | COMPLETED | Acute Myeloid Leukemia |
Gruppo Italiano Malattie EMatologiche dell'Adulto |
2018-10-26 | PHASE2 |
| NCT02858310 | COMPLETED | Papillomavirus Infections; Cervical Intraepithelial Neoplasia; Carcinoma In Situ; Vulvar Neoplasms; Vulvar Diseases |
National Cancer Institute (NCI) |
2017-01-27 | PHASE1; PHASE2 |
| NCT06224049 | UNKNOWN | T-cell Lymphoma |
BGI, China |
2023-12-01 | EARLY_PHASE1 |
| NCT04697940 | ACTIVE_NOT_RECRUITING | Relapsed and Refractory B-cell Non-Hodgkin's Lymphoma; Decitabine-primed Tandem CD19/CD20 CAR T Cells |
Han weidong |
2021-04-15 | PHASE1; PHASE2 |
| NCT04268706 | ACTIVE_NOT_RECRUITING | Hodgkin Lymphoma, Adult; Hodgkin Disease Recurrent; Hodgkin Disease Refractory; Hodgkin Disease, Pediatric |
Tessa Therapeutics |
2021-02-01 | PHASE2 |
| NCT01821781 | ACTIVE_NOT_RECRUITING | Immune Deficiency Disorders; Severe Combined Immunodeficiency; Chronic Granulomatous Disease; X-linked Agammaglobulinemia; Wiskott-Aldrich Syndrome; Hyper-IgM; DiGeorge Syndrome; Chediak-Higashi Syndrome; Common Variable Immune Deficiency; Immune Dysregulatory Disorders; Hemophagocytic Lymphohistiocytosis; IPEX; Autoimmune Lymphoproliferative Syndrome; X-linked Lymphoproliferative Syndrome |
Washington University School of Medicine |
2013-04-29 | PHASE2 |
| NCT01758328 | COMPLETED | Multiple Myeloma |
Memorial Sloan Kettering Cancer Center |
2012-12 | PHASE1 |
| NCT05442580 | TERMINATED | Acute Myeloid Leukemia (AML); Multiple Myeloma (MM) |
University of Pennsylvania |
2023-05-30 | PHASE1 |
| NCT05640713 | UNKNOWN | Allogeneic, CAR-T, Protein Sequestration, Non-gene Edited |
Henan Cancer Hospital |
2022-12-01 | PHASE1 |
| NCT00408447 | UNKNOWN | Sickle Cell Disease; Beta Thalassemia |
Columbia University |
2004-09 | PHASE2 |
| NCT05787535 | UNKNOWN | Cervical Cancer; Head and Neck Squamous Cell Carcinoma; Oropharyngeal Cancer; Vagina Tumor; Carcinoma of Penis; Anal Carcinoma; Carcinoma of Vulva |
HRYZ Biotech Co. |
2023-03-21 | PHASE1 |
| NCT05987696 | COMPLETED | AML, Adult; Minimal Residual Disease |
Institute of Hematology & Blood Diseases Hospital, China |
2023-07-31 | PHASE1 |
| NCT06343376 | TERMINATED | Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Follicular Lymphoma; Recurrent High Grade B-Cell Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Transformed Chronic Lymphocytic Leukemia; Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Diffuse Large B-Cell Lymphoma; Refractory Follicular Lymphoma; Refractory High Grade B-Cell Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Transformed Chronic Lymphocytic Leukemia; Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma |
Roswell Park Cancer Institute |
2024-11-26 | PHASE1 |
| NCT03166397 | UNKNOWN | Malignant Melanoma Stage IV |
Sheba Medical Center |
2017-06-05 | PHASE2 |
| NCT05755854 | UNKNOWN | Hematologic Diseases |
Anhui Provincial Hospital |
2023-05-03 | PHASE1 |
| NCT06247917 | UNKNOWN | Myelodysplastic Syndrome With Excess Blasts-1; Myelodysplastic Syndrome With Excess Blasts-2; Myelodysplastic Syndromes |
Ruijin Hospital |
2024-03-03 | PHASE2 |
| NCT05628883 | COMPLETED | Metastatic Melanoma; Unresectable Melanoma; Acral Melanoma; Mucosal Melanoma; Cutaneous Melanoma; Ocular Melanoma; Uveal Melanoma; Iris Melanoma; Conjunctival Melanoma; Non-Cutaneous Melanoma |
H. Lee Moffitt Cancer Center and Research Institute |
2022-11-22 | PHASE1 |
| NCT05039892 | Not yet recruiting | CholangiocarcinomaAdult |
3D Medicines (Beijing) Co. Ltd.|3D Medicines |
2024-12 | Phase 2 |
| NCT06377293 | Not yet recruiting | End-Stage Kidney Disease |
Far Eastern Memorial Hospital |
2024-11 | Not Applicable |
| NCT05256537 | ACTIVE_NOT_RECRUITING | Hematologic Neoplasms |
Ronald Paquette |
2022-04-26 | PHASE2 |
| NCT01319565 | COMPLETED | Metastatic Melanoma; Skin Cancer |
National Cancer Institute (NCI) |
2011-03-24 | PHASE2 |
| NCT03832127 | RECRUITING | Myeloma |
Nantes University Hospital |
2022-09-09 | PHASE1 |
| NCT05598593 | UNKNOWN | Cytarabine+Thiotepa + Fludarabine + Busulfan; T Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma |
First Affiliated Hospital of Zhejiang University |
2022-10-23 | PHASE2 |
| NCT05032820 | COMPLETED | Multiple Myeloma |
Medical College of Wisconsin |
2022-01-05 | PHASE2 |
| NCT03610490 | TERMINATED | Malignant Solid Neoplasm; Metastatic Colorectal Adenocarcinoma; Metastatic Ovarian Carcinoma; Metastatic Pancreatic Ductal Adenocarcinoma; Platinum-Resistant Ovarian Carcinoma; Recurrent High Grade Ovarian Serous Adenocarcinoma; Recurrent Ovarian Carcinosarcoma; Refractory Colorectal Carcinoma; Stage IV Colorectal Cancer AJCC v8; Stage IVA Colorectal Cancer AJCC v8; Stage IVB Colorectal Cancer AJCC v8; Stage IVC Colorectal Cancer AJCC v8 |
M.D. Anderson Cancer Center |
2018-10-16 | PHASE2 |
| NCT03849651 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia (ALL); Acute Myeloid Leukemia (AML); Myelodysplastic Syndromes (MDS); NK-Cell Leukemia; Hodgkin Lymphoma; Non Hodgkin Lymphoma (NHL); Juvenile Myelomonocytic Leukemia (JMML); Chronic Myeloid Leukemia (CML) |
St. Jude Children's Research Hospital |
2019-01-31 | PHASE2 |
| NCT06398002 | Not yet recruiting | Secondary Hyperparathyroidism|End-stage Kidney Disease |
Iain Bressendorff|Herlev Hospital |
2024-08-01 | Phase 2 |
| NCT06383403 | Not yet recruiting | Primary Biliary Cholangitis |
Ipsen |
2024-07-01 | Phase 3 |
| NCT05797948 | UNKNOWN | Relapsed or Refractory B-cell Non-Hodgkin Lymphoma |
The First Affiliated Hospital of Soochow University |
2022-07-01 | |
| NCT01203722 | COMPLETED | Hematologic Malignancies |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2010-09 | PHASE1; PHASE2 |
| NCT04789408 | TERMINATED | Acute Myeloid Leukemia |
Kite, A Gilead Company |
2021-07-19 | PHASE1 |
| NCT04029688 | TERMINATED | Acute Myeloid Leukemia (AML); Acute Lymphoblastic Leukemia (ALL); Neuroblastoma; Solid Tumors |
Hoffmann-La Roche |
2020-01-27 | PHASE1; PHASE2 |
| NCT06302439 | Not yet recruiting | Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency|ATP-Binding Cassette Subfamily C Member 6 Deficiency |
Inozyme Pharma|GACI Global |
2024-05 | -- |
| NCT03277729 | ACTIVE_NOT_RECRUITING | Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Follicular Lymphoma; Recurrent Lymphoplasmacytic Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Diffuse Large B-Cell Lymphoma; Refractory Follicular Lymphoma; Refractory Lymphoplasmacytic Lymphoma; Refractory Mantle Cell Lymphoma; Refractory Transformed Non-Hodgkin Lymphoma; Recurrent Transformed B-Cell Non-Hodgkin Lymphoma; Recurrent Transformed Chronic Lymphocytic Leukemia; Refractory Marginal Zone Lymphoma; Refractory Transformed B-Cell Non-Hodgkin Lymphoma; Refractory Transformed Chronic Lymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Small Lymphocytic Lymphoma; Recurrent Central Nervous System Lymphoma; Refractory Central Nervous System Lymphoma |
Fred Hutchinson Cancer Center |
2017-12-05 | PHASE1; PHASE2 |
| NCT04611126 | TERMINATED | Metastatic Ovarian Cancer; Metastatic Fallopian Tube Cancer; Peritoneal Cancer |
Inge Marie Svane |
2021-04-22 | PHASE1; PHASE2 |
| NCT03967223 | ACTIVE_NOT_RECRUITING | Neoplasms |
USWM CT, LLC |
2019-12-31 | PHASE2 |
| NCT06703346 | COMPLETED | Neoplasms |
USWM CT, LLC |
2019-12-31 | PHASE2 |
| NCT05170828 | WITHDRAWN | Acute Leukemia; Myelodysplastic Syndromes; T-lymphoblastic Lymphoma; Acute Lymphocytic Leukemia; Acute Myeloid Leukemia; Acute Biphenotypic Leukemia; Acute Undifferentiated Leukemia |
Ossium Health, Inc. |
2022-09 | PHASE1 |
| NCT05649618 | UNKNOWN | Solid Tumor |
Fujian Cancer Hospital |
2022-12-05 | EARLY_PHASE1 |
| NCT02950051 | COMPLETED | Chronic Lymphocytic Leukemia |
German CLL Study Group |
2016-12-13 | PHASE3 |
| NCT05207722 | TERMINATED | Metastatic HER2 Positive Gastroesophageal Junction Cancer |
Celularity Incorporated |
2022-04-14 | PHASE1; PHASE2 |
| NCT02566304 | COMPLETED | Acute Myeloid Leukemia; Acute Myeloid Leukemia in Remission; Aplastic Anemia; Chronic Myelomonocytic Leukemia; Hodgkin Lymphoma; Indolent Non-Hodgkin Lymphoma; Malignant Neoplasm; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Plasma Cell Myeloma; Refractory Anemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Ring Sideroblasts; Refractory Cytopenia With Multilineage Dysplasia; Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2015-11-13 | PHASE2 |
| NCT04191187 | COMPLETED | Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia; Biphenotypic Acute Leukemia; Undifferentiated Leukemia; Prolymphocytic Leukemia; Myelodysplastic Syndromes; Chronic Myelogenous Leukemia; Myeloproliferative Neoplasm; Relapsed Large Cell Lymphoma; Mantle Cell Lymphoma; Hodgkin Lymphoma; Burkitt Lymphoma; Relapsed T-Cell Lymphoma; Relapsed Chronic Lymphocytic Leukemia; Relapsed Small Lymphocytic Lymphoma; Relapsed Marginal B-cell Lymphoma; Relapsed Follicular Lymphoma; Lymphoplasmacytic Lymphoma |
H. Lee Moffitt Cancer Center and Research Institute |
2019-12-06 | PHASE2 |
| NCT03642626 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Large B-cell Lymphoma |
Masonic Cancer Center, University of Minnesota |
2018-12-18 | PHASE2 |
| NCT03743246 | TERMINATED | Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Non-Hodgkin |
Celgene |
2018-10-17 | PHASE1; PHASE2 |
| NCT04904237 | UNKNOWN | Refractory Acute Myeloid Leukemia |
Shanghai Jiao Tong University School of Medicine |
2021-01-01 | PHASE2 |
| NCT04825496 | UNKNOWN | Relapsed or Refractory Acute Lymphoblastic Leukemia |
Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd |
2021-04-09 | PHASE1 |
| NCT05665075 | UNKNOWN | AML, Adult |
Zhejiang University |
2022-12-24 | PHASE1 |
| NCT02047578 | UNKNOWN | Acute Lymphoblastic Leukemia |
Seoul National University Hospital |
2014-02-05 | PHASE2 |
| NCT05453552 | UNKNOWN | Myelodysplastic Syndrome; Allogeneic Hematopoietic Stem Cell Transplantation; Conditioning |
Nanfang Hospital, Southern Medical University |
2022-07-01 | PHASE2; PHASE3 |
| NCT04112589 | UNKNOWN | Acute Myeloid Leukemia |
PETHEMA Foundation |
2019-12-26 | PHASE1; PHASE2 |
| NCT04023071 | TERMINATED | Acute Myelogenous Leukemia; B-cell Lymphoma |
Fate Therapeutics |
2019-10-04 | PHASE1 |
| NCT04665076 | UNKNOWN | Plasma Cell Tumors |
Hebei Senlang Biotechnology Inc., Ltd. |
2020-10-22 | |
| NCT05000450 | TERMINATED | Relapsed/Refractory Multiple Myeloma |
Allogene Therapeutics |
2021-06-06 | PHASE1; PHASE2 |
| NCT04551885 | TERMINATED | Solid Tumor, Adult |
Fate Therapeutics |
2020-09-07 | PHASE1 |
| NCT01810588 | COMPLETED | Hematologic Malignancies |
Weill Medical College of Cornell University |
2012-10-16 | PHASE2 |
| NCT05225831 | UNKNOWN | CD19+ and CD 22+ B-ALL |
Hebei Senlang Biotechnology Inc., Ltd. |
2021-08-15 | EARLY_PHASE1 |
| NCT02348216 | COMPLETED | Refractory Diffuse Large B Cell Lymphoma (DLBCL); Relapsed Diffuse Large B-Cell Lymphoma; Transformed Follicular Lymphoma (TFL); Primary Mediastinal B-cell Lymphoma (PMBCL); High Grade B-cell Lymphoma (HGBCL) |
Kite, A Gilead Company |
2015-04-21 | PHASE1; PHASE2 |
| NCT03852498 | COMPLETED | Cerebral Adrenoleukodystrophy (CALD) |
Genetix Biotherapeutics Inc. |
2019-01-24 | PHASE3 |
| NCT04614636 | TERMINATED | Acute Myeloid Leukemia; AML, Adult; Multiple Myeloma; Myeloma |
Fate Therapeutics |
2020-10-17 | PHASE1 |
| NCT05601830 | TERMINATED | Minimal Residual Disease |
Institute of Hematology & Blood Diseases Hospital, China |
2022-10-09 | PHASE1 |
| NCT03233854 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia; CD19 Positive; Minimal Residual Disease; Philadelphia Chromosome Positive |
Stanford University |
2017-09-01 | PHASE1 |
| NCT04052334 | COMPLETED | Sarcoma |
H. Lee Moffitt Cancer Center and Research Institute |
2019-09-27 | PHASE1 |
| NCT04109482 | TERMINATED | Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) |
Mustang Bio |
2020-02-17 | PHASE1; PHASE2 |
| NCT02766465 | COMPLETED | Sickle Cell Disease |
Medical College of Wisconsin |
2017-03-16 | PHASE2 |
| NCT04632316 | UNKNOWN | Acute Myeloid Leukemia |
Glycostem Therapeutics BV |
2020-12-08 | PHASE1; PHASE2 |
| NCT04626752 | UNKNOWN | Relapsed or Refractory Multiple Myeloma |
Hebei Senlang Biotechnology Inc., Ltd. |
2020-04-01 | EARLY_PHASE1 |
| NCT03056339 | COMPLETED | B-Lymphoid Malignancies; Acute Lymphocytic Leukemia; Chronic Lymphocytic Leukemia; Non-hodgkin Lymphoma |
M.D. Anderson Cancer Center |
2017-06-21 | PHASE1; PHASE2 |
| NCT02722668 | COMPLETED | Acute Leukemia; Acute Myeloid Leukemia; Acute Lymphoblastic Leukemia/Lymphoma; Burkitt's Lymphoma; Natural Killer Cell Malignancies; Chronic Myelogenous Leukemia; Myelodysplastic Syndrome; Large-cell Lymphoma; Hodgkin Lymphoma; Multiple Myeloma; Relapsed Chronic Lymphocytic Leukemia; Relapsed Small Lymphocytic Lymphoma; Marginal Zone B-cell Lymphoma; Follicular Lymphoma; Lymphoplasmacytic Lymphoma; Mantle-cell Lymphoma; Prolymphocytic Leukemia; Bone Marrow Failure Syndromes; Myeloproliferative Neoplasms/Myelofibrosis; Biphenotypic/Undifferentiated/Prolymphocytic Leukemias; MRD Positive Leukemia; Leukemia or MDS in Aplasia; Relapsed T-Cell Lymphoma; Relapsed Multiple Myeloma; Plasma Cell Leukemia |
Masonic Cancer Center, University of Minnesota |
2017-05-15 | PHASE2 |
| NCT02960646 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Aplastic Anemia; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Lymphoblastic Lymphoma; Myelodysplastic Syndrome; Myeloproliferative Neoplasm; Plasma Cell Myeloma; Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma; Recurrent Hodgkin Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Plasma Cell Myeloma; Therapy-Related Myelodysplastic Syndrome |
M.D. Anderson Cancer Center |
2017-01-18 | PHASE1 |
| NCT00790413 | UNKNOWN | Neuroblastoma |
Lund University Hospital |
2005-08 | EARLY_PHASE1 |
| NCT04029038 | WITHDRAWN | CD19 Positive; CD22 Positive; Minimal Residual Disease; Progressive Disease; Recurrent B Acute Lymphoblastic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Non-Hodgkin Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Non-Hodgkin Lymphoma |
M.D. Anderson Cancer Center |
2019-05-15 | PHASE1; PHASE2 |
| NCT04083170 | TERMINATED | Acute Erythroid Leukemia; Acute Lymphoblastic Leukemia; Acute Megakaryoblastic Leukemia; Acute Myeloid Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Hematopoietic and Lymphoid Cell Neoplasm; HIV Infection; Myelodysplastic Syndrome; Myelodysplastic Syndrome With Excess Blasts; Non-Hodgkin Lymphoma; Refractory Anemia |
Fred Hutchinson Cancer Center |
2022-10-06 | PHASE2 |
| NCT05943990 | TERMINATED | Neoplasms |
Adaptimmune |
2020-12-21 | PHASE1 |
| NCT05084027 | UNKNOWN | Hematologic Malignancy; Older Patients; Allogeneic Hematopoietic Stem Cell Transplantation |
First Affiliated Hospital of Zhejiang University |
2021-10-07 | PHASE2 |
| NCT04395222 | ACTIVE_NOT_RECRUITING | Hematologic Malignancy; Bone Marrow Transplant |
Weill Medical College of Cornell University |
2020-10-07 | PHASE2 |
| NCT05016063 | UNKNOWN | Leukemia, Myeloid, Acute |
Xinqiao Hospital of Chongqing |
2021-09-01 | EARLY_PHASE1 |
| NCT02278887 | COMPLETED | Metastatic Melanoma |
The Netherlands Cancer Institute |
2014-09-23 | PHASE3 |
| NCT04002115 | TERMINATED | Acute Myeloid Leukemia |
Milton S. Hershey Medical Center |
2020-06-03 | PHASE2 |
| NCT03873805 | ACTIVE_NOT_RECRUITING | Castration-Resistant Prostate Carcinoma; Metastatic Prostate Carcinoma; Stage IV Prostate Cancer AJCC v8; Stage IVA Prostate Cancer AJCC v8; Stage IVB Prostate Cancer AJCC v8 |
City of Hope Medical Center |
2019-08-20 | PHASE1 |
| NCT03384225 | UNKNOWN | High Risk Acute Myeloid Leukemia; Allogeneic Hematopoeitic Stem Cell Transplantation |
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine |
2016-08-01 | PHASE3 |
| NCT03697824 | WITHDRAWN | Neoplasms |
GlaxoSmithKline |
2019-02-25 | PHASE2 |
| NCT03935347 | WITHDRAWN | Metastatic Bladder Urothelial Carcinoma; Metastatic Renal Pelvis Urothelial Carcinoma; Metastatic Ureter Urothelial Carcinoma; Metastatic Urethral Urothelial Carcinoma; Unresectable Renal Pelvis Urothelial Carcinoma; Unresectable Ureter Urothelial Carcinoma |
Roswell Park Cancer Institute |
2019-06-20 | PHASE2 |
| NCT01904136 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Acute Myeloid Leukemia With Gene Mutations; Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; de Novo Myelodysplastic Syndrome; Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Therapy-Related Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2014-04-22 | PHASE1; PHASE2 |
| NCT03513328 | COMPLETED | Bone Marrow Failure Syndrome; Thalassemia; Sickle Cell Disease; Diamond Blackfan Anemia; Acquired Neutropenia in Newborn; Acquired Anemia Hemolytic; Acquired Thrombocytopenia; Hemophagocytic Lymphohistiocytoses; Wiskott-Aldrich Syndrome; Chronic Granulomatous Disease; Common Variable Immunodeficiency; X-linked Lymphoproliferative Disease; Severe Combined Immunodeficiency; Hurler Syndrome; Mannosidosis; Adrenoleukodystrophy |
University of Florida |
2018-06-15 | PHASE1; PHASE2 |
| NCT02248597 | COMPLETED | Graft Versus Host Disease; Hematopoietic/Lymphoid Cancer |
Wake Forest University Health Sciences |
2015-02-25 | PHASE2 |
| NCT01898793 | TERMINATED | Leukemia, Myeloid, Acute |
Washington University School of Medicine |
2014-08-11 | PHASE1; PHASE2 |
| NCT00796068 | COMPLETED | Acute Biphenotypic Leukemia; Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia in Remission; Blasts Under 5 Percent of Bone Marrow Nucleated Cells; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Myelodysplastic Syndrome (MDS) |
Fred Hutchinson Cancer Center |
2009-02-24 | PHASE2 |
| NCT03335241 | UNKNOWN | Ovarian Cancer |
Sun Yat-sen University |
2017-03-01 | PHASE2 |
| NCT02529813 | COMPLETED | Acute Biphenotypic Leukemia; Acute Lymphoblastic Leukemia; Blasts 5 Percent or More of Bone Marrow Nucleated Cells; CD19 Positive; Minimal Residual Disease; Non-Hodgkin Lymphoma; Small Lymphocytic Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage IV Chronic Lymphocytic Leukemia |
M.D. Anderson Cancer Center |
2015-12-16 | PHASE1 |
| NCT04088864 | COMPLETED | B Cell Lymphoma; Acute Lymphoblastic Leukemia, Pediatric; Lymphoma |
Kara Lynn Davis |
2020-01-10 | PHASE1 |
| NCT03504410 | TERMINATED | Relapsed/Refractory Acute Myeloid Leukemia |
Cornerstone Pharmaceuticals |
2018-11-12 | PHASE3 |
| NCT03813147 | COMPLETED | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Recurrent Myelodysplastic Syndrome; Refractory Acute Myeloid Leukemia; Refractory Myelodysplastic Syndrome |
National Cancer Institute (NCI) |
2019-05-17 | PHASE1 |
| NCT01019876 | COMPLETED | Bone Marrow Failure; Osteopetrosis; Fanconi Anemia; Severe Combined Immunodeficiency |
Columbia University |
2002-09 | PHASE2; PHASE3 |
| NCT03882203 | COMPLETED | Refractory Hematologic Cancer; Allogeneic Stem Cell Transplantation |
Shanghai Jiao Tong University School of Medicine |
2018-08-01 | PHASE2 |
| NCT02918292 | COMPLETED | Severe Aplastic Anemia |
Medical College of Wisconsin |
2017-07-03 | PHASE2 |
| NCT01033552 | COMPLETED | Epidermolysis Bullosa |
Masonic Cancer Center, University of Minnesota |
2010-01 | PHASE1; PHASE2 |
| NCT03994705 | TERMINATED | Multiple Myeloma |
Cartesian Therapeutics |
2019-08-01 | PHASE1 |
| NCT03579888 | TERMINATED | B Acute Lymphoblastic Leukemia With t(v;11q23.3); KMT2A Rearranged; Recurrent B Acute Lymphoblastic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Recurrent Mantle Cell Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Ph-Like Acute Lymphoblastic Leukemia; Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory Chronic Lymphocytic Leukemia; Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified; Refractory Mantle Cell Lymphoma; Refractory Non-Hodgkin Lymphoma; Refractory Ph-Like Acute Lymphoblastic Leukemia; Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma; Refractory Small Lymphocytic Lymphoma |
M.D. Anderson Cancer Center |
2020-06-26 | PHASE1 |
| NCT04205240 | TERMINATED | Recurrent Plasma Cell Myeloma |
Srinivas Devarakonda |
2020-12-22 | PHASE2 |
| NCT03704298 | TERMINATED | Relapsed/Refractory Large B-cell Lymphoma |
Kite, A Gilead Company |
2018-11-20 | PHASE1 |
| NCT03338972 | COMPLETED | Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma |
Fred Hutchinson Cancer Center |
2017-11-29 | PHASE1 |
| NCT02718755 | WITHDRAWN | Hematologic Malignancy |
M.D. Anderson Cancer Center |
2018-05 | PHASE2 |
| NCT03391466 | COMPLETED | Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) |
Kite, A Gilead Company |
2018-01-25 | PHASE3 |
| NCT02096614 | COMPLETED | Solid Tumors |
Mie University |
2014-04 | PHASE1 |
| NCT03412526 | UNKNOWN | Metastatic Ovarian Cancer |
Sheba Medical Center |
2018-01-21 | PHASE2 |
| NCT04536922 | WITHDRAWN | Metastatic HPV-16 Positive Squamous Cell Anal Cancer |
National Cancer Institute (NCI) |
2021-01-27 | PHASE2 |
| NCT00472329 | UNKNOWN | Graft Failure |
Colorado Blood Cancer Institute |
2007-03 | PHASE2 |
| NCT03615144 | TERMINATED | Non-Malignant Hematologic Disorders |
Memorial Sloan Kettering Cancer Center |
2018-07-23 | PHASE2 |
| NCT00629798 | COMPLETED | Acute Myeloid Leukemia; Advanced Myelodysplastic Syndromes |
Memorial Sloan Kettering Cancer Center |
2008-02-12 | PHASE2 |
| NCT03958656 | COMPLETED | Myeloma-Multiple; Myeloma, Plasma-Cell |
National Cancer Institute (NCI) |
2019-06-13 | PHASE1 |
| NCT00352976 | COMPLETED | Fanconi Anemia |
Masonic Cancer Center, University of Minnesota |
2006-05-18 | PHASE2; PHASE3 |
| NCT03344705 | UNKNOWN | Hematological Malignancies |
Beijing Immunochina Medical Science & Technology Co., Ltd. |
2017-08-21 | PHASE1 |
| NCT04303520 | UNKNOWN | CD19-positive ALL |
The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine |
2018-05-03 | PHASE1 |
| NCT03706547 | UNKNOWN | Multiple Myeloma in Relapse; Multiple Myeloma Progression |
Peng Liu |
2018-10-30 | PHASE1 |
| NCT03716856 | UNKNOWN | Refractory or Relapsed Multiple Myeloma |
First Affiliated Hospital of Zhejiang University |
2018-03-23 | PHASE1 |
| NCT01967823 | COMPLETED | Melanoma; Meningioma; Breast Cancer; Non-Small Cell Lung Cancer; Hepatocellular Cancer |
National Cancer Institute (NCI) |
2013-10-24 | PHASE2 |
| NCT03399448 | TERMINATED | Multiple Myeloma; Melanoma; Synovial Sarcoma; Myxoid/Round Cell Liposarcoma |
University of Pennsylvania |
2018-09-05 | PHASE1 |
| NCT04008888 | UNKNOWN | Multiple Myeloma; Plasma Cell Leukemia; Extramedullary Plasmacytoma; Loss of Chromosome 17p; t(14;16); t(4;14); T(14;20); 1Q21 Amplification; Complex Karyotype |
Institute of Hematology & Blood Diseases Hospital, China |
2018-01-05 | |
| NCT02181478 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myelogenous Leukemia; Myelodysplastic Syndromes; Myelofibrosis; Relapsed Non-Hodgkin Lymphoma; Refractory Non-Hodgkin Lymphoma; Hodgkin Lymphoma; Refractory Hodgkin Lymphoma; Relapsed Chronic Lymphocytic Leukemia; Refractory Chronic Lymphocytic Leukemia; Lymphoid Malignancies; Chronic Myelogenous Leukemia |
Case Comprehensive Cancer Center |
2015-07-22 | EARLY_PHASE1 |
| NCT00902044 | ACTIVE_NOT_RECRUITING | Sarcoma |
Baylor College of Medicine |
2010-02-11 | PHASE1 |
| NCT02456350 | UNKNOWN | Chronic Lymphocytic Leukemia; Acute Lymphocytic Leukemia; Lymphoma |
Shenzhen Second People's Hospital |
2015-04 | PHASE1 |
| NCT00812669 | COMPLETED | Leukemia |
Cancer Trials Ireland |
2008-08-18 | PHASE2 |
| NCT03434704 | COMPLETED | Transplant-Related Hematologic Malignancy; Leukemia, Acute; Myelodysplastic Syndromes; Graft Vs Host Disease; Fungal Infection |
Ciceri Fabio |
2018-06-18 | PHASE2 |
| NCT03593902 | TERMINATED | Systemic Sclerosis; Scleroderma |
Northwestern University |
2018-05-17 | PHASE2; PHASE3 |
| NCT03093168 | UNKNOWN | Multiple Myeloma |
The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine |
2017-02-15 | PHASE1 |
| NCT02439788 | WITHDRAWN | Neuroblastoma |
Baylor College of Medicine |
2017-08 | PHASE1 |
| NCT00309842 | COMPLETED | Acute Myeloid Leukemia; Acute Lymphocytic Leukemia; Chronic Myelogenous Leukemia; Myelofibrosis; MDS; Refractory Anemia; Chronic Lymphocytic Leukemia; Prolymphocytic Leukemia; Non-Hodgkin's Lymphoma; Leukemia; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes |
Masonic Cancer Center, University of Minnesota |
2005-07-28 | PHASE2 |
| NCT03661515 | COMPLETED | Acute Myeloid Leukemia |
PETHEMA Foundation |
2018-07-17 | PHASE1 |
| NCT02280525 | COMPLETED | Leukemia |
M.D. Anderson Cancer Center |
2015-03-05 | PHASE1 |
| NCT02924753 | UNKNOWN | B-cell Acute Lymphoblastic Leukemia |
Henan Cancer Hospital |
2016-07-18 | PHASE1 |
| NCT02916979 | COMPLETED | Leukemia, Lymphoid; Leukemia, Myeloid; Myelodysplastic Syndromes; Myelofibrosis; Lymphoma, Malignant; Multiple Myeloma; Waldenstrom Macroglobulinemia |
Dartmouth-Hitchcock Medical Center |
2016-09-06 | PHASE1 |
| NCT03208556 | UNKNOWN | Relapsed or Refractory B-cell Lymphoma |
Peking University |
2017-06-21 | PHASE1 |
| NCT02215967 | COMPLETED | Myeloma, Plasma-Cell; Myeloma-Multiple |
National Cancer Institute (NCI) |
2014-08-12 | PHASE1 |
| NCT02627573 | TERMINATED | Leukemia, Chronic Myeloid; Myelodysplastic Syndromes; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative |
St. Petersburg State Pavlov Medical University |
2015-07 | PHASE2 |
| NCT03029273 | UNKNOWN | Lung Cancer, Nonsmall Cell, Recurrent |
Guangzhou Institute of Respiratory Disease |
2017-03-21 | PHASE1 |
| NCT02435901 | COMPLETED | Sickle Cell Disease; Beta Thalassemia-Major |
Northwell Health |
2008-12 | PHASE1; PHASE2 |
| NCT01570348 | TERMINATED | Crohn Disease |
Fred Hutchinson Cancer Center |
2012-07-17 | PHASE2 |
| NCT02642965 | COMPLETED | Acute Myeloid Leukemia Post Cytotoxic Therapy; Recurrent Childhood Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia |
Children's Oncology Group |
2016-05-02 | PHASE1; PHASE2 |
| NCT02070406 | TERMINATED | Unspecified Adult Solid Tumor, Protocol Specific |
Jonsson Comprehensive Cancer Center |
2014-07-17 | PHASE1 |
| NCT01251575 | COMPLETED | Adult Acute Lymphoblastic Leukemia; Adult Acute Myeloid Leukemia; Adult Diffuse Large B-Cell Lymphoma; Adult Myelodysplastic Syndrome; Adult Non-Hodgkin Lymphoma; Aggressive Non-Hodgkin Lymphoma; Childhood Acute Lymphoblastic Leukemia; Childhood Acute Myeloid Leukemia; Childhood Diffuse Large B-Cell Lymphoma; Childhood Myelodysplastic Syndrome; Childhood Non-Hodgkin Lymphoma; Chronic Lymphocytic Leukemia; Chronic Lymphocytic Leukemia in Remission; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Hematopoietic and Lymphoid Cell Neoplasm; Mantle Cell Lymphoma; Plasma Cell Myeloma; Prolymphocytic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Refractory Chronic Lymphocytic Leukemia; T-Cell Prolymphocytic Leukemia; Waldenstrom Macroglobulinemia; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Hodgkin Lymphoma |
Fred Hutchinson Cancer Center |
2010-12-01 | PHASE2 |
| NCT01527045 | COMPLETED | Aggressive Non-Hodgkin Lymphoma; Blasts Under 5 Percent of Bone Marrow Nucleated Cells; Chronic Lymphocytic Leukemia; Loss of Chromosome 17p; Myelodysplastic/Myeloproliferative Neoplasm; Non-Hodgkin Lymphoma; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Aggressive Adult Non-Hodgkin Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Recurrent Diffuse Large B-Cell Lymphoma; Recurrent Hodgkin Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Non-Hodgkin Lymphoma; Recurrent Plasma Cell Myeloma; Recurrent Small Lymphocytic Lymphoma; Waldenstrom Macroglobulinemia |
Fred Hutchinson Cancer Center |
2012-09-25 | PHASE2 |
| NCT02652468 | COMPLETED | Lymphoma |
University of Wisconsin, Madison |
2016-03-10 | |
| NCT00943800 | COMPLETED | Leukemia; Myelodysplastic Syndrome; Multiple Myeloma; Lymphoma |
University of Chicago |
2006-10-09 | |
| NCT02659943 | COMPLETED | Lymphoma, B-Cell; Lymphoma, Non-hodgkins |
National Cancer Institute (NCI) |
2016-01-21 | PHASE1 |
| NCT01079013 | UNKNOWN | Non Hodgkin Lymphoma; Hodgkin Lymphoma |
Sheba Medical Center |
2010-03 | PHASE2 |
| NCT02626338 | COMPLETED | Relapsed/Refractory Acute Myeloid Leukemia (AML) |
Arog Pharmaceuticals, Inc. |
2016-02 | PHASE1; PHASE2 |
| NCT02145039 | TERMINATED | Acute Leukemias; Burkitt's Lymphoma; Chronic Myelogenous Leukemia |
Masonic Cancer Center, University of Minnesota |
2014-10 | |
| NCT02685670 | UNKNOWN | Hematopoietic/Lymphoid Cancer; Adult Acute Lymphoblastic Leukemia in Remission; B-cell Adult Acute Lymphoblastic Leukemia; B-cell Chronic Lymphocytic Leukemia; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Refractory Chronic Lymphocytic Leukemia; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma |
The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine |
2016-02 | PHASE1; PHASE2 |
| NCT00943319 | COMPLETED | Leukemia; Lymphoma; Myeloma |
University of Chicago |
2012-03 | PHASE1; PHASE2 |
| NCT01598025 | TERMINATED | Acute Leukemia; Chronic Leukemia; Myelodysplastic Syndrome; Non-Hodgkins Lymphoma |
Memorial Sloan Kettering Cancer Center |
2012-05-02 | |
| NCT02529839 | UNKNOWN | Multiple Sclerosis |
Hadassah Medical Organization |
2015-10 | |
| NCT01653717 | COMPLETED | Advanced Cancers; Leukemia |
M.D. Anderson Cancer Center |
2013-06-11 | PHASE1 |
| NCT02653196 | TERMINATED | Neuroepithelial Tumor; Solid Tumor; Allogeneic Hematopoietic Stem Cell Transplantation |
Montefiore Medical Center |
2015-09 | EARLY_PHASE1 |
| NCT02194374 | WITHDRAWN | Leukemia |
M.D. Anderson Cancer Center |
2015-01 | PHASE1 |
| NCT02199041 | TERMINATED | Hematological Malignancies |
St. Jude Children's Research Hospital |
2014-07-11 | PHASE2 |
| NCT02390739 | WITHDRAWN | Metastatic Thyroid Cancer |
National Cancer Institute (NCI) |
2015-03-02 | PHASE1; PHASE2 |
| NCT01875237 | TERMINATED | Leukemia; Myeloma; Myeloproliferative Diseases |
M.D. Anderson Cancer Center |
2013-12-27 | PHASE1; PHASE2 |
| NCT01592981 | COMPLETED | Waldenstrom's Macroglobulinaemia |
University College, London |
2013-01 | PHASE2 |
| NCT02614560 | TERMINATED | Acute Myeloid Leukemia |
Seagen Inc. |
2015-11 | PHASE1; PHASE2 |
| NCT02410551 | TERMINATED | Myeloproliferative Diseases |
M.D. Anderson Cancer Center |
2015-06-15 | PHASE2 |
| NCT01445821 | TERMINATED | Scleroderma, Systemic |
Northwestern University |
2011-09-15 | PHASE3 |
| NCT02577094 | WITHDRAWN | Lymphocyte B CD22 Positive Acute Lymphoblastic Leukemia |
Nantes University Hospital |
PHASE1; PHASE2 | |
| NCT02178683 | UNKNOWN | Graft Versus Host Disease |
Colorado Blood Cancer Institute |
2010-11 | PHASE3 |
| NCT00686556 | COMPLETED | Acute Lymphoblastic Leukemia; Myelodysplastic Syndrome; Multiple Myeloma |
Masonic Cancer Center, University of Minnesota |
2012-08 | PHASE1 |
| NCT00498316 | COMPLETED | Myelodysplastic Syndrome; Leukemia |
M.D. Anderson Cancer Center |
2007-07-03 | PHASE1 |
| NCT00918723 | COMPLETED | Chronic Lymphocytic Leukemia; Stage I Chronic Lymphocytic Leukemia; Stage I Small Lymphocytic Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Small Lymphocytic Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Small Lymphocytic Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Small Lymphocytic Lymphoma |
Fred Hutchinson Cancer Center |
2009-06 | PHASE1; PHASE2 |
| NCT01071239 | COMPLETED | Fanconi Anemia |
Medical College of Wisconsin |
2009-04 | PHASE2 |
| NCT01582048 | TERMINATED | Patients Receiving Mismatched Allogeneic HCT |
Prof. Dr. med. Wolfgang Bethge |
2012-04 | PHASE2 |
| NCT02111863 | TERMINATED | Melanoma; Skin Cancer |
National Cancer Institute (NCI) |
2014-02-21 | PHASE2 |
| NCT02489266 | WITHDRAWN | Metastatic Melanoma |
National Cancer Institute (NCI) |
2015-06-24 | PHASE1 |
| NCT00545714 | COMPLETED | Leukemia, Lymphocytic, Chronic, B-Cell |
Hoffmann-La Roche |
2007-11-21 | PHASE2 |
| NCT01271010 | TERMINATED | Lymphocytic Leukemia, Chronic |
Hoffmann-La Roche |
2011-06-17 | PHASE4 |
| NCT01435343 | COMPLETED | Acute Myeloblastic Leukemia |
PETHEMA Foundation |
2012-07 | PHASE1; PHASE2 |
| NCT01283386 | TERMINATED | Lymphocytic Leukemia, Chronic |
Hoffmann-La Roche |
2011-04-27 | PHASE4 |
| NCT02127905 | WITHDRAWN | Fanconi Anemia |
Neena Kapoor, M.D. |
2011-03 | |
| NCT00566696 | COMPLETED | Leukemia, Acute Lymphocytic (ALL); Leukemia, Myeloid, Acute(AML); Leukemia, Myeloid, Chronic(CML); Juvenile Myelomonocytic Leukemia (JMML); Hemoglobinuria, Paroxysmal Nocturnal (PNH); Hodgkin Lymphoma; Lymphoma, Non-Hodgkin (NHL); Myelodysplastic Syndrome (MDS) |
St. Jude Children's Research Hospital |
2007-12-14 | PHASE2 |
| NCT00727415 | COMPLETED | Chronic Lymphocytic Leukemia |
Gruppo Italiano Malattie EMatologiche dell'Adulto |
2008-02 | PHASE1; PHASE2 |
| NCT02105116 | TERMINATED | Adult Acute Megakaryoblastic Leukemia (M7); Adult Acute Minimally Differentiated Myeloid Leukemia (M0); Adult Acute Monoblastic Leukemia (M5a); Adult Acute Monocytic Leukemia (M5b); Adult Acute Myeloblastic Leukemia With Maturation (M2); Adult Acute Myeloblastic Leukemia Without Maturation (M1); Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Acute Myelomonocytic Leukemia (M4); Adult Erythroleukemia (M6a); Adult Pure Erythroid Leukemia (M6b); Recurrent Adult Acute Myeloid Leukemia; Untreated Adult Acute Myeloid Leukemia |
Rutgers, The State University of New Jersey |
2014-02 | |
| NCT00448357 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
UNC Lineberger Comprehensive Cancer Center |
2005-10 | PHASE1; PHASE2 |
| NCT02024308 | UNKNOWN | Acute Myeloid Leukemia; AML1-ETO Fusion Protein Expression |
Changhai Hospital |
2010-11 | PHASE4 |
| NCT01312376 | TERMINATED | Ovarian Carcinoma; Fallopian Tube Cancer; Primary Peritoneal Cancer |
Abramson Cancer Center at Penn Medicine |
2011-03 | PHASE1 |
| NCT00924326 | COMPLETED | Primary Mediastinal B-cell Lymphoma; Diffuse, Large B-cell Lymphoma; Diffuse Large B-Cell Lymphoma Transformed From Follicular Lymphoma; Mantle Cell |
National Cancer Institute (NCI) |
2009-02-17 | PHASE1; PHASE2 |
| NCT00881556 | TERMINATED | Epidermolysis Bullosa |
Columbia University |
2009-08-20 | EARLY_PHASE1 |
| NCT00597519 | COMPLETED | Cancer; Leukemia; Myelodysplastic Syndrome; Non-Hodgkin's Lymphoma |
Memorial Sloan Kettering Cancer Center |
2006-03 | PHASE2 |
| NCT01020734 | COMPLETED | Leukemia |
Asan Medical Center |
2011-05 | PHASE2 |
| NCT00968461 | WITHDRAWN | Leukemia; Lymphoproliferative Disorders |
M.D. Anderson Cancer Center |
2013-05 | PHASE1 |
| NCT00679536 | UNKNOWN | Leukemia |
Ann & Robert H Lurie Children's Hospital of Chicago |
2008-05 | PHASE1; PHASE2 |
| NCT02259348 | TERMINATED | Acute Lymphoblastic Leukemia (ALL); Acute Myeloid Leukemia (AML); Myeloid Sarcoma; Chronic Myelogenous Leukemia (CML); Juvenile Myelomonocytic Leukemia (JMML); Myelodysplastic Syndrome (MDS); Non-Hodgkin Lymphoma (NHL) |
St. Jude Children's Research Hospital |
2014-10 | PHASE2 |
| NCT01703364 | COMPLETED | CLL; Chronic Lymphocytic Leukemia |
Arbeitsgemeinschaft medikamentoese Tumortherapie |
2012-06 | PHASE1; PHASE2 |
| NCT01236573 | TERMINATED | Skin Cancer; Metastatic Melanoma |
National Institutes of Health Clinical Center (CC) |
2010-10 | PHASE1; PHASE2 |
| NCT00455312 | COMPLETED | Dyskeratosis Congenita; Aplastic Anemia |
Masonic Cancer Center, University of Minnesota |
2007-08 | PHASE2; PHASE3 |
| NCT01145976 | UNKNOWN | Aplastic Anemia |
Cooperative Study Group A for Hematology |
2010-03 | PHASE3 |
| NCT01658319 | COMPLETED | Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Peripheral T-cell Lymphoma; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage III Chronic Lymphocytic Leukemia; Testicular Lymphoma; Waldenström Macroglobulinemia |
Case Comprehensive Cancer Center |
2011-05 | PHASE1 |
| NCT00824265 | COMPLETED | Leukaemia, Lymphocytic, Chronic |
Novartis Pharmaceuticals |
2009-03-12 | PHASE3 |
| NCT01493453 | TERMINATED | CD19 Positive Non-Hodgkin Lymphoma |
The Christie NHS Foundation Trust |
2008-03 | PHASE1 |
| NCT00794820 | COMPLETED | Chronic Lymphocytic Leukemia |
M.D. Anderson Cancer Center |
2003-12 | PHASE2 |
| NCT00469144 | COMPLETED | Myelodysplastic Syndrome; Leukemia; Acute Myeloid Leukemia |
M.D. Anderson Cancer Center |
2005-06 | PHASE3 |
| NCT00448019 | COMPLETED | Chronic Lymphocytic Leukemia |
M.D. Anderson Cancer Center |
2007-02 | PHASE2 |
| NCT00051311 | COMPLETED | Hematologic Neoplasms |
National Cancer Institute (NCI) |
2003-01-03 | PHASE2 |
| NCT00602693 | COMPLETED | Leukemia; Lymphoma; Multiple Myeloma; Plasma Cell Neoplasm; Myelodysplastic Syndromes |
Masonic Cancer Center, University of Minnesota |
2007-07-23 | PHASE1 |
| NCT01218867 | TERMINATED | Metastatic Cancer; Metastatic Melanoma; Renal Cancer |
National Cancer Institute (NCI) |
2010-11-10 | PHASE1; PHASE2 |
| NCT01370772 | COMPLETED | B-cell Chronic Lymphocytic Leukemia CLL |
French Innovative Leukemia Organisation |
2011-05 | PHASE2 |
| NCT00119366 | TERMINATED | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Childhood Myelodysplastic Syndromes; Chronic Myelomonocytic Leukemia; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Myeloid Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Refractory Anemia With Excess Blasts; Refractory Anemia With Excess Blasts in Transformation; Refractory Anemia With Ringed Sideroblasts; Refractory Cytopenia With Multilineage Dysplasia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes |
Fred Hutchinson Cancer Center |
2003-05 | PHASE2 |
| NCT01518153 | TERMINATED | Leukemia; Lymphoma; Myeloma; Myeloproliferative Diseases |
M.D. Anderson Cancer Center |
2012-02 | PHASE2 |
| NCT00036738 | COMPLETED | Adult Acute Lymphoblastic Leukemia in Remission; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Blastic Phase; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Phase of Disease; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Disease |
Fred Hutchinson Cancer Center |
2001-07-13 | PHASE2 |
| NCT00387959 | COMPLETED | Leukemia; Lymphoma |
Memorial Sloan Kettering Cancer Center |
2006-07 | PHASE2 |
| NCT01313689 | COMPLETED | Leukaemia |
Novartis Pharmaceuticals |
2011-04-14 | PHASE3 |
| NCT00089011 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Blastic Phase Chronic Myelogenous Leukemia; Childhood Acute Lymphoblastic Leukemia in Remission; Childhood Acute Myeloid Leukemia in Remission; Childhood Burkitt Lymphoma; Childhood Chronic Myelogenous Leukemia; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Childhood Myelodysplastic Syndromes; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Chronic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; Cutaneous B-cell Non-Hodgkin Lymphoma; de Novo Myelodysplastic Syndromes; Essential Thrombocythemia; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Polycythemia Vera; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Primary Myelofibrosis; Prolymphocytic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Refractory Multiple Myeloma; Relapsing Chronic Myelogenous Leukemia; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Childhood Anaplastic Large Cell Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Lymphoblastic Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Multiple Myeloma; Stage I Small Lymphocytic Lymphoma; Stage IA Mycosis Fungoides/Sezary Syndrome; Stage IB Mycosis Fungoides/Sezary Syndrome; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Childhood Anaplastic Large Cell Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Lymphoblastic Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Multiple Myeloma; Stage IIA Mycosis Fungoides/Sezary Syndrome; Stage IIB Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Childhood Anaplastic Large Cell Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Lymphoblastic Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Multiple Myeloma; Stage III Small Lymphocytic Lymphoma; Stage IIIA Mycosis Fungoides/Sezary Syndrome; Stage IIIB Mycosis Fungoides/Sezary Syndrome; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Childhood Anaplastic Large Cell Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Lymphoblastic Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Small Lymphocytic Lymphoma; Stage IVA Mycosis Fungoides/Sezary Syndrome; Stage IVB Mycosis Fungoides/Sezary Syndrome; Testicular Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Adult Acute Myeloid Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia; Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies; Waldenström Macroglobulinemia |
Fred Hutchinson Cancer Center |
2004-04 | PHASE2 |
| NCT00645606 | COMPLETED | Leukemia |
University Hospital, Tours |
2007-12 | PHASE3 |
| NCT00075478 | COMPLETED | Acute Lymphoblastic Leukemia in Remission; Acute Myeloid Leukemia in Remission; Aggressive Non-Hodgkin Lymphoma; Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Diffuse Large B-Cell Lymphoma; Hematopoietic and Lymphoid Cell Neoplasm; Indolent Non-Hodgkin Lymphoma; Mantle Cell Lymphoma; Myelodysplastic/Myeloproliferative Neoplasm; Plasma Cell Myeloma; Refractory Chronic Lymphocytic Leukemia; Refractory Hodgkin Lymphoma; Waldenstrom Macroglobulinemia |
Fred Hutchinson Cancer Center |
2003-10 | PHASE3 |
| NCT01622556 | TERMINATED | Hematologic Malignancies |
University of Virginia |
2012-01 | PHASE2 |
| NCT01247688 | WITHDRAWN | Lymphoid Hematological Malignancies; Umbilical Cord Blood Transplant |
Baylor College of Medicine |
2010-11 | |
| NCT01274195 | UNKNOWN | Hematopoietic Stem Cell Transplantation |
Seoul National University Hospital |
2011-01 | PHASE2 |
| NCT01338675 | UNKNOWN | Chronic Granulomatous Disease |
Seoul National University Hospital |
2011-01 | PHASE1; PHASE2 |
| NCT01455506 | COMPLETED | Acute Myeloid Leukemia; Myelodysplastic Syndrome |
Hackensack Meridian Health |
2009-05 | PHASE1 |
| NCT00076752 | COMPLETED | Lupus Erythematosus, Systemic |
National Cancer Institute (NCI) |
2004-01-30 | PHASE2 |
| NCT01322776 | UNKNOWN | Mantle Cell Lymphoma Recurrent |
Sun Yat-sen University |
2011-03 | PHASE1; PHASE2 |
| NCT00544466 | ACTIVE_NOT_RECRUITING | Leukemia; Myelodysplastic Syndromes |
City of Hope Medical Center |
2006-07-31 | PHASE1; PHASE2 |
| NCT00612612 | TERMINATED | B-cell Chronic Lymphocytic Leukemia; Leukemia; Prolymphocytic Leukemia; Refractory Chronic Lymphocytic Leukemia; Stage I Chronic Lymphocytic Leukemia; Stage II Chronic Lymphocytic Leukemia; Stage III Chronic Lymphocytic Leukemia; Stage IV Chronic Lymphocytic Leukemia |
National Cancer Institute (NCI) |
2008-01 | PHASE1 |
| NCT00453388 | COMPLETED | Acute Myeloid Leukemia in Remission; de Novo Myelodysplastic Syndrome; Fanconi Anemia; Previously Treated Myelodysplastic Syndrome |
Fred Hutchinson Cancer Center |
2007-02 | PHASE2 |
| NCT00536341 | COMPLETED | Chronic Lymphocytic Leukemia |
SCRI Development Innovations, LLC |
2008-01 | PHASE1; PHASE2 |
| NCT00513474 | COMPLETED | Chronic Myeloproliferative Disorders; Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Massachusetts General Hospital |
2008-01 | PHASE1 |
| NCT01300247 | COMPLETED | Lymphocytic Leukemia, Chronic |
Genentech, Inc. |
2011-05 | PHASE1 |
| NCT01044745 | TERMINATED | Accelerated Phase Chronic Myelogenous Leukemia; Adult Acute Lymphoblastic Leukemia in Remission; Adult Acute Myeloid Leukemia in Remission; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Blastic Phase Chronic Myelogenous Leukemia; Contiguous Stage II Adult Burkitt Lymphoma; Contiguous Stage II Adult Diffuse Large Cell Lymphoma; Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Contiguous Stage II Adult Lymphoblastic Lymphoma; Contiguous Stage II Grade 1 Follicular Lymphoma; Contiguous Stage II Grade 2 Follicular Lymphoma; Contiguous Stage II Grade 3 Follicular Lymphoma; Contiguous Stage II Mantle Cell Lymphoma; Contiguous Stage II Marginal Zone Lymphoma; Contiguous Stage II Small Lymphocytic Lymphoma; de Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Graft Versus Host Disease; Nodal Marginal Zone B-cell Lymphoma; Noncontiguous Stage II Adult Burkitt Lymphoma; Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma; Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma; Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Grade 1 Follicular Lymphoma; Noncontiguous Stage II Grade 2 Follicular Lymphoma; Noncontiguous Stage II Grade 3 Follicular Lymphoma; Noncontiguous Stage II Mantle Cell Lymphoma; Noncontiguous Stage II Marginal Zone Lymphoma; Noncontiguous Stage II Small Lymphocytic Lymphoma; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Relapsing Chronic Myelogenous Leukemia; Secondary Myelodysplastic Syndromes; Splenic Marginal Zone Lymphoma; Stage I Adult Burkitt Lymphoma; Stage I Adult Diffuse Large Cell Lymphoma; Stage I Adult Diffuse Mixed Cell Lymphoma; Stage I Adult Diffuse Small Cleaved Cell Lymphoma; Stage I Adult Immunoblastic Large Cell Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage I Adult T-cell Leukemia/Lymphoma; Stage I Chronic Lymphocytic Leukemia; Stage I Cutaneous T-cell Non-Hodgkin Lymphoma; Stage I Grade 1 Follicular Lymphoma; Stage I Grade 2 Follicular Lymphoma; Stage I Grade 3 Follicular Lymphoma; Stage I Mantle Cell Lymphoma; Stage I Marginal Zone Lymphoma; Stage I Mycosis Fungoides/Sezary Syndrome; Stage I Small Lymphocytic Lymphoma; Stage II Adult T-cell Leukemia/Lymphoma; Stage II Chronic Lymphocytic Leukemia; Stage II Cutaneous T-cell Non-Hodgkin Lymphoma; Stage II Mycosis Fungoides/Sezary Syndrome; Stage III Adult Burkitt Lymphoma; Stage III Adult Diffuse Large Cell Lymphoma; Stage III Adult Diffuse Mixed Cell Lymphoma; Stage III Adult Diffuse Small Cleaved Cell Lymphoma; Stage III Adult Immunoblastic Large Cell Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage III Adult T-cell Leukemia/Lymphoma; Stage III Chronic Lymphocytic Leukemia; Stage III Cutaneous T-cell Non-Hodgkin Lymphoma; Stage III Grade 1 Follicular Lymphoma; Stage III Grade 2 Follicular Lymphoma; Stage III Grade 3 Follicular Lymphoma; Stage III Mantle Cell Lymphoma; Stage III Marginal Zone Lymphoma; Stage III Mycosis Fungoides/Sezary Syndrome; Stage III Small Lymphocytic Lymphoma; Stage IV Adult Burkitt Lymphoma; Stage IV Adult Diffuse Large Cell Lymphoma; Stage IV Adult Diffuse Mixed Cell Lymphoma; Stage IV Adult Diffuse Small Cleaved Cell Lymphoma; Stage IV Adult Immunoblastic Large Cell Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Stage IV Adult T-cell Leukemia/Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma; Stage IV Grade 1 Follicular Lymphoma; Stage IV Grade 2 Follicular Lymphoma; Stage IV Grade 3 Follicular Lymphoma; Stage IV Mantle Cell Lymphoma; Stage IV Marginal Zone Lymphoma; Stage IV Mycosis Fungoides/Sezary Syndrome; Stage IV Small Lymphocytic Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Adult Acute Myeloid Leukemia; Waldenström Macroglobulinemia |
University of Nebraska |
2009-12-10 | PHASE2 |
| NCT01273181 | TERMINATED | Metastatic Cancer; Metastatic Renal Cancer; Metastatic Melanoma |
National Cancer Institute (NCI) |
2010-12 | PHASE1; PHASE2 |
| NCT01191957 | COMPLETED | Acute Myeloid Leukemia (AML) |
Gruppo Italiano Trapianto di Midollo Osseo |
2008-01 | PHASE3 |
| NCT00615589 | TERMINATED | Multiple Myeloma; Plasma Cell Leukemia |
University of Michigan Rogel Cancer Center |
2008-02 | PHASE2 |
| NCT00822770 | COMPLETED | Stem Cell Transplantation; Leukemia |
M.D. Anderson Cancer Center |
2009-01 | PHASE1; PHASE2 |
| NCT00882323 | UNKNOWN | Aplastic Anemia |
The Korean Society of Pediatric Hematology Oncology |
2008-11 | PHASE2 |
| NCT02013817 | COMPLETED | Lymphocytic Leukemia, Chronic |
Hoffmann-La Roche |
2005-10-11 | PHASE2 |
| NCT00947388 | TERMINATED | Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; Stage III Chronic Lymphocytic Leukemia; Stage III Small Lymphocytic Lymphoma; Stage IV Chronic Lymphocytic Leukemia; Stage IV Small Lymphocytic Lymphoma |
Case Comprehensive Cancer Center |
2008-11 | PHASE1 |
| NCT00963872 | TERMINATED | Leukemia; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes |
Masonic Cancer Center, University of Minnesota |
2010-03 | PHASE1; PHASE2 |
| NCT00454480 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
The University of New South Wales |
2006-08 | PHASE2; PHASE3 |
| NCT00737685 | UNKNOWN | Anemia, Aplastic |
The Korean Society of Pediatric Hematology Oncology |
2006-01 | PHASE2 |
| NCT00959231 | UNKNOWN | Hematopoietic/Lymphoid Cancer |
Cancer Research UK |
2009-01 | PHASE2 |
| NCT01105273 | COMPLETED | Aplastic Anemia |
Asan Medical Center |
2009-07 | PHASE1; PHASE2 |
| NCT00941928 | TERMINATED | Leukemia; Pediatric Cancer |
M.D. Anderson Cancer Center |
2009-07 | PHASE2 |
| NCT01135329 | TERMINATED | Lymphoma; Leukemia; Myelodysplastic Syndrome |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2010-08 | PHASE2 |
| NCT00887042 | UNKNOWN | Acute Myeloid Leukemia |
The Korean Society of Pediatric Hematology Oncology |
2006-06 | PHASE1; PHASE2 |
| NCT00322101 | COMPLETED | Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome; Acute Myeloid Leukemia/Transient Myeloproliferative Disorder; Adult Acute Myeloid Leukemia in Remission; Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities; Adult Acute Myeloid Leukemia With Del(5q); Adult Acute Myeloid Leukemia With Inv(16)(p13;q22); Adult Acute Myeloid Leukemia With t(15;17)(q22;q12); Adult Acute Myeloid Leukemia With t(16;16)(p13;q22); Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); Childhood Acute Myeloid Leukemia in Remission; Childhood Myelodysplastic Syndromes; de Novo Myelodysplastic Syndromes; Myelodysplastic Syndrome With Isolated Del(5q); Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Previously Treated Myelodysplastic Syndromes; Recurrent Adult Acute Myeloid Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Secondary Acute Myeloid Leukemia; Secondary Myelodysplastic Syndromes |
Fred Hutchinson Cancer Center |
2006-01 | PHASE3 |
| NCT00589563 | COMPLETED | Chronic Myeloproliferative Disorders; Graft Versus Host Disease; Infection; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms; Precancerous Condition; Secondary Myelofibrosis; Small Intestine Cancer |
City of Hope Medical Center |
2007-05 | PHASE2 |
| NCT01392079 | COMPLETED | Chronic Lymphocytic Leukemia |
University of Ulm |
2008-02 | PHASE2 |
| NCT00815568 | UNKNOWN | AML; MDS; ALL; CML; Lymphoma |
Samsung Medical Center |
2008-08 | PHASE2 |
| NCT00807196 | UNKNOWN | Non-Hodgkins Lymphoma |
Maisonneuve-Rosemont Hospital |
2008-09 | PHASE1; PHASE2 |
| NCT00324623 | COMPLETED | Melanoma (Skin) |
Prof. Serge Leyvraz |
2005-09 | PHASE1 |
| NCT01106950 | TERMINATED | Leukemia, Myelogenous, Acute |
Masonic Cancer Center, University of Minnesota |
2010-07 | PHASE2 |
| NCT01359254 | TERMINATED | Hematological Disease |
University of Chicago |
2010-04 | PHASE2 |
| NCT00943293 | TERMINATED | Preleukemia; Myeloproliferative Disorders; Lymphoma; Myeloma; Graft Versus Host Disease |
University of Chicago |
2003-05 | PHASE1 |
| NCT00509288 | COMPLETED | Melanoma; Skin Cancer |
National Cancer Institute (NCI) |
2007-06 | PHASE2 |
| NCT00125606 | TERMINATED | Acute Myeloid Leukemia |
University Hospital Muenster |
2004-10 | PHASE3 |
| NCT00509496 | TERMINATED | Skin Cancer; Melanoma |
National Cancer Institute (NCI) |
2007-06 | PHASE2 |
| NCT00524667 | TERMINATED | Chronic Lymphocytic Leukemia |
CancerCare Manitoba |
2008-01 | PHASE2 |
| NCT00048893 | TERMINATED | Breast Neoplasms; Metastases, Neoplasm |
National Cancer Institute (NCI) |
2002-11 | PHASE1; PHASE2 |
| NCT00915811 | TERMINATED | Myelodysplastic Syndromes; Leukemia, Myeloid, Acute |
King's College Hospital NHS Trust |
2007-06 | PHASE2 |
| NCT00462332 | COMPLETED | Leukemia |
Gruppo Italiano Malattie EMatologiche dell'Adulto |
2007-05 | PHASE2 |
| NCT00392782 | TERMINATED | Leukemia; Myelodysplastic Syndromes |
Masonic Cancer Center, University of Minnesota |
2005-07 | PHASE2 |
| NCT00587054 | COMPLETED | Allogeneic Stem Cell Transplant; Leukemia; Non-Hodgkins; Lymphoblastic Lymphoma; Myelodysplastic Syndrome; Paroxysmal Nocturnal Hemoglobinuria (PNH) |
Memorial Sloan Kettering Cancer Center |
2001-06 | PHASE2 |
| NCT00802568 | COMPLETED | Multiple Myeloma and Plasma Cell Neoplasm |
Institut Paoli-Calmettes |
2007-04 | PHASE2 |
| NCT00562965 | TERMINATED | Lymphoma, Follicular |
Pfizer |
2007-11 | PHASE3 |
| NCT00772486 | COMPLETED | Chronic Lymphocytic Leukemia |
Memgen, LLC |
2008-09 | PHASE1 |
| NCT00054236 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Case Comprehensive Cancer Center |
2002-05 | PHASE1 |
| NCT00381550 | COMPLETED | Accelerated Phase Chronic Myelogenous Leukemia; Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative; Blastic Phase Chronic Myelogenous Leukemia; Chronic Eosinophilic Leukemia; Chronic Myelomonocytic Leukemia; Essential Thrombocythemia; Philadelphia Chromosome Negative Chronic Myelogenous Leukemia; Polycythemia Vera; Primary Myelofibrosis; Relapsing Chronic Myelogenous Leukemia |
National Cancer Institute (NCI) |
2006-08 | PHASE2 |
| NCT00303667 | COMPLETED | Acute Myelogenous Leukemia |
Masonic Cancer Center, University of Minnesota |
2005-01 | PHASE1; PHASE2 |
| NCT00860457 | COMPLETED | Chronic Lymphocytic Leukemia |
Georgetown University |
2008-02 | PHASE2 |
| NCT00644371 | COMPLETED | Non-Hodgkin Lymphoma |
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea |
2007-11 | PHASE2 |
| NCT00448201 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
UNC Lineberger Comprehensive Cancer Center |
2011-01-07 | PHASE2 |
| NCT01082939 | COMPLETED | Chronic Lymphocytic Leukemia |
M.D. Anderson Cancer Center |
2002-12 | PHASE2 |
| NCT00427557 | COMPLETED | Multiple Myeloma; Leukemia; Lymphoma |
M.D. Anderson Cancer Center |
2006-10 | PHASE2 |
| NCT00924001 | TERMINATED | Melanoma; Malignant Melanoma; Melanoma, Experimental |
National Cancer Institute (NCI) |
2007-08 | PHASE1; PHASE2 |
| NCT00060424 | COMPLETED | B-Cell Prolymphocytic Leukemia; Chronic Lymphocytic Leukemia; Prolymphocytic Leukemia; Recurrent Chronic Lymphocytic Leukemia; Recurrent Small Lymphocytic Lymphoma; Refractory Chronic Lymphocytic Leukemia; T-Cell Prolymphocytic Leukemia |
Fred Hutchinson Cancer Center |
2003-03 | PHASE2 |
| NCT01456351 | COMPLETED | Non-Hodgkin's Lymphoma; Mantle Cell Lymphoma |
University of Giessen |
2003-09 | PHASE3 |
| NCT00480987 | TERMINATED | Myelodysplastic Syndromes; Acute Myeloid Leukemia; Leukemia |
M.D. Anderson Cancer Center |
2007-07 | PHASE1; PHASE2 |
| NCT00787761 | COMPLETED | Myeloproliferative Disorders; Kidney Cancer; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Diseases |
Northside Hospital, Inc. |
2007-04 | PHASE2 |
| NCT00450983 | TERMINATED | Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes |
Fred Hutchinson Cancer Center |
2006-12 | PHASE2 |
| NCT00376480 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
Dana-Farber Cancer Institute |
2005-06 | PHASE1 |
| NCT01088724 | COMPLETED | Post-transplant Lymphoproliferative Disease (PTLD); Non Burkitt |
A.O. Ospedale Papa Giovanni XXIII |
2002-02 | PHASE4 |
| NCT00103558 | COMPLETED | Chronic Lymphocytic Leukemia |
Biogen |
2004-03 | PHASE1; PHASE2 |
| NCT00547196 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndromes |
City of Hope Medical Center |
2005-08-16 | |
| NCT00774280 | COMPLETED | Leukemia; Myelodysplastic Syndrome |
Cooperative Study Group A for Hematology |
2002-05 | PHASE3 |
| NCT00054353 | COMPLETED | Refractory Multiple Myeloma |
Fred Hutchinson Cancer Center |
2002-10 | PHASE1; PHASE2 |
| NCT00566332 | COMPLETED | Waldenström Macroglobulinemia; Lymphoplasmacytic Lymphoma; Splenic Marginal Zone Lymphoma |
French Study Group on Chronic Lymphoid Leukemia |
2001-06 | PHASE3 |
| NCT00704938 | TERMINATED | Kidney Cancer; Melanoma (Skin); Unspecified Adult Solid Tumor, Protocol Specific |
National Institutes of Health Clinical Center (CC) |
2008-06 | PHASE2 |
| NCT00652899 | TERMINATED | Fallopian Tube Cancer; Ovarian Cancer; Peritoneal Cavity Cancer |
Masonic Cancer Center, University of Minnesota |
2008-03 | PHASE2 |
| NCT00027560 | COMPLETED | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Memorial Sloan Kettering Cancer Center |
2001-07 | PHASE2 |
| NCT00096382 | COMPLETED | Melanoma (Skin) |
National Institutes of Health Clinical Center (CC) |
2004-09 | PHASE2 |
| NCT00282282 | COMPLETED | Graft Versus Host Disease; GVHD |
Dana-Farber Cancer Institute |
2006-01 | PHASE2 |
| NCT00289549 | COMPLETED | Leukemia, Lymphocytic, Chronic |
BioCryst Pharmaceuticals |
2005-06 | PHASE2 |
| NCT00160355 | COMPLETED | Wiskott-Aldrich Syndrome |
St. Jude Children's Research Hospital |
2005-05 | PHASE1 |
| NCT00274846 | COMPLETED | Leukemia |
Masonic Cancer Center, University of Minnesota |
2005-03 | PHASE2 |
| NCT00104975 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Yale University |
2005-02 | PHASE1 |
| NCT00521430 | COMPLETED | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Nonmalignant Neoplasm; Unspecified Adult Solid Tumor, Protocol Specific |
Asan Medical Center |
2004-04 | |
| NCT00182650 | COMPLETED | Lymphoma |
City of Hope Medical Center |
2004-06 | PHASE1 |
| NCT00608517 | TERMINATED | Graft Versus Host Disease; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
Vanderbilt-Ingram Cancer Center |
2005-09 | |
| NCT00074269 | TERMINATED | Breast Cancer |
University of California, San Diego |
2003-07 | PHASE2 |
| NCT00429026 | TERMINATED | Renal Cell Cancer |
M.D. Anderson Cancer Center |
2004-01 | PHASE2 |
| NCT00121186 | TERMINATED | Lymphoma |
SWOG Cancer Research Network |
2005-07 | PHASE2 |
| NCT00531310 | TERMINATED | Chronic Myeloid Leukemia |
Columbia University |
2003-01 | PHASE2 |
| NCT00038844 | COMPLETED | Lymphoma; Leukemia |
M.D. Anderson Cancer Center |
2001-06 | |
| NCT00004485 | COMPLETED | Sickle Cell Anemia |
Fred Hutchinson Cancer Center |
1999-12 | PHASE1; PHASE2 |
| NCT00423709 | COMPLETED | Hodgkin's Disease |
M.D. Anderson Cancer Center |
1998-01 | |
| NCT00275054 | COMPLETED | Chronic Lymphocytic Leukemia |
German CLL Study Group |
2005-10 | PHASE3 |
| NCT00328861 | COMPLETED | Metastatic Melanoma; Metastatic Kidney Cancer |
National Cancer Institute (NCI) |
2006-05 | PHASE2 |
| NCT00085462 | COMPLETED | Melanoma (Skin) |
National Institutes of Health Clinical Center (CC) |
2004-05 | PHASE1 |
| NCT00301860 | TERMINATED | Leukemia; Lymphoma |
University of California, San Francisco |
2003-01 | |
| NCT00533923 | COMPLETED | AML; ALL; CLL; Myelodysplastic Syndrome; Non-Hodgkin's Lymphoma; Hodgkin's Lymphoma; Multiple Myeloma; Aplastic Anemia; Myeloproliferative Disorder |
Beth Israel Deaconess Medical Center |
2002-12 | PHASE2 |
| NCT00085449 | WITHDRAWN | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Alliance for Clinical Trials in Oncology |
2006-05 | PHASE1; PHASE2 |
| NCT00183989 | TERMINATED | Mantle Cell Lymphoma |
University of Southern California |
2000-08 | PHASE2 |
| NCT00169208 | COMPLETED | Follicular Lymphoma |
Lymphoma Study Association |
2001-04 | PHASE2 |
| NCT00281931 | TERMINATED | Prolymphocytic Leukemia |
German CLL Study Group |
1999-09 | PHASE2 |
| NCT00309881 | COMPLETED | Chronic Lymphocytic Leukemia |
German CLL Study Group |
2003-04 | PHASE2 |
| NCT00220311 | COMPLETED | Leukemia, Lymphocytic, Chronic, B-Cell |
Genzyme, a Sanofi Company |
2000-11 | PHASE4 |
| NCT00006251 | COMPLETED | Acute Undifferentiated Leukemia; Adult Nasal Type Extranodal NK/T-cell Lymphoma; Anaplastic Large Cell Lymphoma; Angioimmunoblastic T-cell Lymphoma; Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Grade III Lymphomatoid Granulomatosis; Childhood Immunoblastic Large Cell Lymphoma; Childhood Myelodysplastic Syndromes; Childhood Nasal Type Extranodal NK/T-cell Lymphoma; Chronic Myelomonocytic Leukemia; Cutaneous B-cell Non-Hodgkin Lymphoma; de Novo Myelodysplastic Syndromes; Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue; Hepatosplenic T-cell Lymphoma; Intraocular Lymphoma; Juvenile Myelomonocytic Leukemia; Mast Cell Leukemia; Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable; Myeloid/NK-cell Acute Leukemia; Nodal Marginal Zone B-cell Lymphoma; Noncutaneous Extranodal Lymphoma; Peripheral T-cell Lymphoma; Post-transplant Lymphoproliferative Disorder; Previously Treated Myelodysplastic Syndromes; Primary Systemic Amyloidosis; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Acute Myeloid Leukemia; Recurrent Adult Burkitt Lymphoma; Recurrent Adult Diffuse Large Cell Lymphoma; Recurrent Adult Diffuse Mixed Cell Lymphoma; Recurrent Adult Diffuse Small Cleaved Cell Lymphoma; Recurrent Adult Grade III Lymphomatoid Granulomatosis; Recurrent Adult Hodgkin Lymphoma; Recurrent Adult Immunoblastic Large Cell Lymphoma; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Adult T-cell Leukemia/Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Anaplastic Large Cell Lymphoma; Recurrent Childhood Grade III Lymphomatoid Granulomatosis; Recurrent Childhood Large Cell Lymphoma; Recurrent Childhood Lymphoblastic Lymphoma; Recurrent Childhood Small Noncleaved Cell Lymphoma; Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma; Recurrent Grade 1 Follicular Lymphoma; Recurrent Grade 2 Follicular Lymphoma; Recurrent Grade 3 Follicular Lymphoma; Recurrent Mantle Cell Lymphoma; Recurrent Marginal Zone Lymphoma; Recurrent Mycosis Fungoides/Sezary Syndrome; Recurrent Renal Cell Cancer; Recurrent Small Lymphocytic Lymphoma; Recurrent/Refractory Childhood Hodgkin Lymphoma; Refractory Chronic Lymphocytic Leukemia; Refractory Hairy Cell Leukemia; Refractory Multiple Myeloma; Small Intestine Lymphoma; Splenic Marginal Zone Lymphoma; Stage II Multiple Myeloma; Stage III Multiple Myeloma; T-cell Large Granular Lymphocyte Leukemia; Testicular Lymphoma; Waldenström Macroglobulinemia |
Fred Hutchinson Cancer Center |
2000-05 | PHASE1; PHASE2 |
| NCT00049075 | COMPLETED | Leukemia |
NCIC Clinical Trials Group |
2002-08-08 | PHASE2 |
| NCT00086775 | COMPLETED | Leukemia |
Bayer |
2003-07 | PHASE2 |
| NCT00005941 | COMPLETED | Cervical Cancer; Vaginal Cancer |
Fred Hutchinson Cancer Center |
1999-11 | PHASE2 |
| NCT00056966 | COMPLETED | Hematologic Malignancy |
Baylor College of Medicine |
2002-11 | PHASE1; PHASE2 |
| NCT00005802 | COMPLETED | Leukemia |
Fred Hutchinson Cancer Center |
1999-06 | PHASE1; PHASE2 |
| NCT00082940 | COMPLETED | Leukemia |
Wake Forest University Health Sciences |
2002-08 | PHASE2 |
| NCT00060684 | COMPLETED | Lymphoma, Low-Grade; Lymphoma, Small Lymphocytic; Lymphoma, Mixed-Cell, Follicular; Lymphoma, Small Cleaved-Cell, Follicular |
CTI BioPharma |
2001-12 | PHASE1 |
| NCT00262782 | COMPLETED | Chronic Lymphocytic Leukemia |
German CLL Study Group |
1997-04 | PHASE3 |
| NCT00005851 | COMPLETED | Recurrent Renal Cell Cancer; Stage IV Renal Cell Cancer |
Fred Hutchinson Cancer Center |
2000-02 | PHASE1; PHASE2 |
| NCT00004145 | COMPLETED | Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
University of Chicago |
1998-11 | PHASE2 |
| NCT00048399 | TERMINATED | Graft Failure |
Baylor College of Medicine |
2000-12 | PHASE1; PHASE2 |
| NCT00055653 | COMPLETED | Leukemia; Lymphoma; Myelodysplastic Syndromes; Myelodysplastic-Myeloproliferative Diseases |
Roswell Park Cancer Institute |
2003-01 | PHASE2 |
| NCT00276848 | COMPLETED | Chronic Lymphocytic Leukemia |
German CLL Study Group |
1999-07 | PHASE3 |
| NCT00056979 | TERMINATED | Inherited Metabolic Storage Diseases |
Baylor College of Medicine |
2002-06 | PHASE1; PHASE2 |
| NCT00041288 | TERMINATED | Leukemia; Lymphoma |
University of Texas Southwestern Medical Center |
2001-10 | PHASE2 |
| NCT00005593 | COMPLETED | Leukemia; Myelodysplastic Syndromes |
Case Comprehensive Cancer Center |
1998-09 | PHASE1 |
| NCT00003829 | COMPLETED | Leukemia |
Alliance for Clinical Trials in Oncology |
1999-08 | PHASE2 |
| NCT00021151 | COMPLETED | Leukemia |
Case Comprehensive Cancer Center |
2000-01 | |
| NCT00004255 | COMPLETED | Graft Versus Host Disease; Leukemia; Myelodysplastic Syndromes |
Chimeric Therapies |
2000-03 | PHASE2; PHASE3 |
| NCT00001422 | COMPLETED | Arthritis, Psoriatic; Psoriasis |
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) |
1995-06 | PHASE2 |
| NCT00859001 | COMPLETED | Follicular Lymphoma |
University of Bologna |
PHASE2 | |
| NCT00228852 | COMPLETED | T-Cell Immune Deficiency Diseases; Severe Combined Immunodeficiency |
Emory University |
PHASE1; PHASE2 | |
| NCT00382694 | UNKNOWN | Multiple Myeloma |
Nordic Myeloma Study Group |
2005-05 | PHASE2 |
| NCT00006250 | UNKNOWN | Lymphoma |
Lymphoma Trials Office |
2000-05 | PHASE3 |
| NCT00317759 | COMPLETED | Melanoma (Skin) |
Fred Hutchinson Cancer Center |
2003-05 | PHASE1 |
| NCT00140569 | COMPLETED | Follicular Lymphoma |
Lymphoma Study Association |
1994-01 | PHASE3 |
| NCT00488709 | COMPLETED | Acute Myeloid Leukemia |
PETHEMA Foundation |
2003-05 | PHASE4 |
| NCT00845104 | WITHDRAWN | B-cell Chronic Lymphocytic Leukemia; Refractory Chronic Lymphocytic Leukemia |
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium |
2009-01 | PHASE2 |
| NCT00304720 | UNKNOWN | Multiple Myeloma; Lymphoma; Acute Myelogenous Leukemia; Acute Lymphocytic Leukemia; Myelodysplastic Syndrome |
Colorado Blood Cancer Institute |
2004-03 | PHASE2 |
| NCT00080925 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
National Institutes of Health Clinical Center (CC) |
2004-02 | PHASE1 |
| NCT00559221 | UNKNOWN | Acute Myeloid Leukemia |
Cooperative Study Group A for Hematology |
2004-12 | PHASE2 |
| NCT00004218 | COMPLETED | Leukemia |
Leukemia Research Fund |
1999-10 | PHASE3 |
| NCT00199147 | UNKNOWN | Acute Myeloid Leukemia |
Johann Wolfgang Goethe University Hospital |
2000-01 | PHASE4 |
| NCT00024440 | COMPLETED | Leukemia |
Genta Incorporated |
2001-07 | PHASE3 |
| NCT00110058 | COMPLETED | Leukemia |
Fred Hutchinson Cancer Center |
2005-02 | PHASE2 |
| NCT00001676 | COMPLETED | Glomerulonephritis; Lupus Nephritis; Systemic Lupus Erythematosus |
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) |
1998-01 | PHASE1 |
| NCT00006233 | COMPLETED | Melanoma (Skin) |
Fred Hutchinson Cancer Center |
2000-01 | PHASE2 |
| NCT00156858 | UNKNOWN | Hematologic Malignancy |
Alberta Health services |
1998-01 |
(data from https://clinicaltrials.gov, updated on 2026-08-24)
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
- Fludarabine (NSC 118218) Phosphate Solubility in DMSO
- Fludarabine (NSC 118218) Phosphate Stock Solution
- Fludarabine (NSC 118218) Phosphate Storage
- Fludarabine (NSC 118218) Phosphate Stability
- Fludarabine (NSC 118218) Phosphate Molecular Weight
- Fludarabine (NSC 118218) Phosphate SMILES
- Fludarabine (NSC 118218) Phosphate CAS Number
- Fludarabine (NSC 118218) Phosphate Chemical Structure (2D and 3D)
- Fludarabine (NSC 118218) Phosphate SDS|MSDS