FK866 (Daporinad) is a potent and specific NAMPT inhibitor. It affects NAD+ biosynthesis and NF-κB signaling pathways by depleting intracellular NAD+ and ATP levels, effectively inhibiting cancer cell proliferation and promoting apoptosis.
FK866 (Daporinad) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for FK866 (Daporinad) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.