CAS No. 162359-55-9

Batch: Purity:99.97
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Fingolimod (FTY-720) Chemical Structure
Chemical Structure
Check the Fingolimod (FTY-720) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol
CAS Number 162359-55-9
Molecular Formula

C19H33NO2
Molecular Weight (MW) 307.47
SMILES CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N
InChIKey KKGQTZUTZRNORY-UHFFFAOYSA-N

Ordering Information

Biological Activity

Fingolimod (FTY-720) is a potent sphingosine 1-phosphate (S1P) receptor modulator that undergoes phosphorylation in vivo to form its active metabolite. This active form binds to S1P receptor subtypes, triggering receptor internalization and desensitization. Consequently, Fingolimod inhibits lymphocyte egress from secondary lymphoid organs into circulation, downregulating peripheral lymphocyte counts and attenuating neuroinflammatory immune responses through S1P receptor signaling pathways. [1][2]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 13 mg/mL (42.28 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 5 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.